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Hot Topics of the Day|PHGKB
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10/15/2019

Hot Topics of the Day are picked by experts to capture the latest information and publications on public health genomics and precision health for various diseases and health topics. Sources include published scientific literature, reviews, blogs and popular press articles.

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Archived Hot Topics of the Day By Date

Those Probiotics May Actually Be Hurting Your ‘Gut Health’
L Cohen, WSJ, October 2019

The newly fashionable pills and foods meant to increase the variety of healthy bacteria in our bodies can actually have the opposite effect.

A Drug Was Made For Just One Child, Raising Hopes About Future Of Tailored Medicine
A Chen, WBUR, October 11, 2019

“This is a kind of fantasy that we all had at the beginning of this field more than 30 years ago. Reading this paper is like reading [science-fiction author] Jules Verne. It’s a futuristic experiment.” The apparent success of milasen is stunning proof of how designer genetic drugs, known as antisense oligonucleotides, can be personalized for individuals.

Exome Sequencing Reveals a High Prevalence of BRCA1 and BRCA2 Founder Variants in a Diverse Population-Based Biobank
NS Abul-Husn et al, BioRXIV, October 13, 2019

The study investigated BRCA1/2 prevalence and impact using exome sequencing and electronic health record (EHR) data from 30,223 adult participants of the BioMe Biobank in New York City. There were 218 (0.7%) individuals harboring expected pathogenic variants, resulting in an overall prevalence of 1 in 139.

New insights into malaria susceptibility from the genomes of 17,000 individuals from Africa, Asia, and Oceania
Malaria Genomic Epidemiology Network, BioRXIV, October 14, 2019

A genome-wide association study of host resistance to severe Plasmodium falciparum malaria in over 17,000 individuals from 11 malaria-endemic countries shows a newly implicated variant on chromosome 6 associated with risk of cerebral malaria, and the discovery of an erythroid-specific transcription start site.

People at High Risk For Flu Complications
CDC, 2019 Brand

Most people who get sick with flu will have mild illness, will not need medical care or antiviral drugs and will recover in less than two weeks. Some people, however, are more likely to get flu complications that can result in hospitalization and sometimes death.

Technology approaches to digital health literacy.
Dunn Patrick et al. International journal of cardiology 2019 Oct 294-296

Digital health literacy is an extension of health literacy and uses the same operational definition. Technology solutions have the potential to promote health literacy. Technology solutions should go beyond building literacy and numeracy skills to functional and critical skills, such as navigating the healthcare system, communication and shared decision making.


Disclaimer: Articles listed in Hot Topics of the Day are selected by Public Health Genomics Branch to provide current awareness of the scientific literature and news. Inclusion in the update does not necessarily represent the views of the Centers for Disease Control and Prevention nor does it imply endorsement of the article's methods or findings. CDC and DHHS assume no responsibility for the factual accuracy of the items presented. The selection, omission, or content of items does not imply any endorsement or other position taken by CDC or DHHS. Opinion, findings and conclusions expressed by the original authors of items included in the Clips, or persons quoted therein, are strictly their own and are in no way meant to represent the opinion or views of CDC or DHHS. References to publications, news sources, and non-CDC Websites are provided solely for informational purposes and do not imply endorsement by CDC or DHHS.
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