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PHGKB News
- New CDC Blog: Your Top 10 Public Health Genomics Knowledge Base Searches in 2018! (12/30/2018)
- New release of PHGKB (11/13/2018) (v5.2) (11/13/2018)
- New release of PHGKB (10/19/2018) (v5.1) (10/19/2018)
- New CDC blog about GRANTOMICS. (10/07/2018)
Last Posted: Jan-20-2019 8AM
Microbiome
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The respiratory microbiome and susceptibility to influenza virus infection.
Lee Kyu Han et al. PloS one 2019 (1) e0207898
The role of the microbiota in infectious diseases.
Libertucci Josie et al. Nature microbiology 2019 Jan (1) 35-45
Effect of Fecal Microbiota Transplantation on 8-Week Remission in Patients With Ulcerative Colitis
A Randomized Clinical Trial
SP Costello et al, JAMA, January 15, 2019
Manipulating the Microbiome With Fecal Transplantation to Treat Ulcerative Colitis
CR Kelley et al, JAMA, January 15, 2019
More information on this topic
Rare Diseases
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UK Biobank Dataset Helps Elucidate Pathogenicity of Rare Genetic Variants
GenomeWeb, January 17, 2019
Insights into genetics, human biology and disease gleaned from family based genomic studies
JE Posey et al, Genetics in Medicine, January 18, 2019
NCATS Genetic and Rare Diseases Information Center
PHGKB now provides direct links to GARD information by disease and other search terms, January 2019
Next-Generation Sequencing to Diagnose Suspected Genetic Disorders.
et al. The New England journal of medicine 2019 Jan 380(2) 200-201
More information on this topic
Genetic Risk Score
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Improved polygenic prediction by Bayesian multiple regression on summary statistics
LR Llyod-Jones et al, BIOXRIV, January 2019
BOADICEA: a comprehensive breast cancer risk prediction model incorporating genetic and nongenetic risk factors
A Lee et al, Genetics in Medicine, January 15, 2019
The illusion of polygenic risk prediction
N Wald et al, Genetics in Medicine, January 12, 2019
A Polygenic Risk Score Derived From Episodic Memory Weighted Genetic Variants Is Associated With Cognitive Decline in Preclinical Alzheimer's Disease.
Porter Tenielle et al. Frontiers in aging neuroscience 2018 10423
More information on this topic
Heart Diseases
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Genetic factor may identify patients at risk for spontaneous coronary artery dissection
DL Bhatt, Healio, January 2019
Is Heart Disease Genetic?
L Meyers, Genome Medical, December 2018
Simple blood and saliva tests that cost just £40 could help prevent heart attacks, scientists say
B Spencer, Daily Mail, October 8, 2018
Genomic Risk Prediction of Coronary Artery Disease in 480,000 Adults: Implications for Primary Prevention
M Inouye et al, JACC< October 2018
More information on this topic
Economics
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Value of genetic testing in the prevention of coronary heart disease events
Y Hynninen et al, PLOS One, January 2019
Estimating the burden and economic impact of pediatric genetic disease
N Gonzaludo et al, Genetics in Medicine, December 19, 2018
High price of precision medicine forces cancer patients to make agonizing choices
L Szabo, USA Today, October 26, 2018
Direct health-care costs for children diagnosed with genetic diseases are significantly higher than for children with other chronic diseases.
Marshall Deborah A et al. Genetics in medicine : official journal of the American College of Medical Genetics 2018 Sep
More information on this topic
Cervical Cancer
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Using Artificial Intelligence to Detect Cervical Cancer
NIH Director's Blog, January 17, 2019
Preventing Cervical Cancer in the 21st Century
CDC Public Health Grand Rounds, January 15, 2018
The precision prevention and therapy of HPV-related cervical cancer: new concepts and clinical implications.
Hu Zheng et al. Cancer medicine 2018 Oct (10) 5217-5236
Final Recommendation Statement Cervical Cancer Screening,
U.S. Preventative Services Task Force, August 2018
More information on this topic
Diabetes
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Development and Standardization of an Improved Type 1 Diabetes Genetic Risk Score for Use in Newborn Screening and Incident Diagnosis.
Sharp Seth A et al. Diabetes care 2019 Jan
The National Diabetes Prevention Program Changing Lifestyles to Prevent Type 2 Diabetes
CDC Grand Rounds, November 13, 2018, 1pm ET
Precision Healthcare of Type 2 Diabetic Patients Through Implementation of Haptoglobin Genotyping.
Bale Bradley F et al. Frontiers in cardiovascular medicine 2018 5141
Gene mutation points to new way to fight diabetes, obesity, heart disease
NIH, October 9, 2018
More information on this topic
Suicide
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Genetic associations with suicide attempt severity and genetic overlap with major depression.
Levey Daniel F et al. Translational psychiatry 2019 Jan (1) 22
Novel genome-wide associations for suicidality in UK Biobank, genetic correlation with psychiatric disorders and polygenic association with completed suicide.
RJ Strawbridge et al, BIORXIV, October 25, 2018
Genome-wide significant regions in 43 Utah high-risk families implicate multiple genes involved in risk for completed suicide
H Coon et al, Mol Psychiatry, October 23, 2018
Genome-wide association study of suicide attempt in psychiatric disorders identifies association with major depression polygenic risk scores
N Mullins et al, BioRXIV Preprints, September 2018
More information on this topic
Precision Medicine
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All of Us Research Program Expands Data Collection Efforts with Fitbit
NIH, January 16, 2018
Precision medicine advances in 2019
E Mardis, AACR, January 2019
Precision Medicine Approaches and the Health of Populations: Study Design Concerns and Considerations.
Galea Sandro et al. Perspectives in biology and medicine 2018 61(4) 527-536
The Precision Medicine Bubble
Special Issue of Perspectives in Biology and Medicine, JHU Press, 2018
More information on this topic
Newborn Screening
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A Chat about Babyseq
AJHG, January 17, 2019
Baby sequencing steps
L Koch, Nature Reviews Genetics, January 16, 2019
The Future of Newborn Screening: Why and How Partnerships Will Be Needed for Success.
Bailey Donald B et al. North Carolina medical journal 80(1) 28-31
Newborn Screening Policy Decisions: Adding Conditions.
Shone Scott M et al. North Carolina medical journal 80(1) 42-44
More information on this topic
Precision Public Health
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A collaborative multiyear, multimodel assessment of seasonal influenza forecasting in the United States.
Reich Nicholas G et al. Proceedings of the National Academy of Sciences of the United States of America 2019 Jan
Place-Based Inequity in Smoking Prevalence in the Largest Cities in the United States
EC Leas et al, JAMA Internal Medicine, January 2019
Improved state-level influenza nowcasting in the United States leveraging Internet-based data and network approaches
FS Lu et al, Nature Communications, January 11, 2019
From high definition precision healthcare to precision public oral health: opportunities and challenges.
Slavkin Harold C et al. Journal of public health dentistry 2018 Dec
More information on this topic
Genetic Testing
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Why Prevention Is The Next Frontier Of Genetic Testing
Forbes, January 17, 2019
A Systematic Review of the Psychological Implications of Genetic Testing: A Comparative Analysis Among Cardiovascular, Neurodegenerative and Cancer Diseases.
Oliveri Serena et al. Frontiers in genetics 2018 624
What Secrets Can Genetic Tests Really Reveal?
S Collins, WebMD, December 27, 2018
Patient re-contact after revision of genomic test results: points to consider-a statement of the American College of Medical Genetics and Genomics (ACMG).
David Karen L et al. Genetics in medicine : official journal of the American College of Medical Genetics 2018 Dec
More information on this topic
Whole Genome Sequencing
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Tens of thousands in Hong Kong to have their DNA sequenced in government-backed genome project
South China Post, January 17, 2019
Views from the clinic: Healthcare provider perspectives on whole genome sequencing in paediatrics.
Szego M J et al. European journal of medical genetics 2018 Nov
100,000 whole genomes sequenced in the NHS
UK Government, Department of Health, December 5, 2018
UK Researchers Just Finished Sequencing 100,000 Human Genomes
K Houser, Futurism, December 7, 2018
More information on this topic
Personal Genomics
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23andMe is offering pharmacogenetic testing, but is it any good?
Precision Medicine Advisors, January 16, 2019
Genetic testing is the future of healthcare, but many experts say companies like 23andMe are doing more harm than good
E Brodwin, Business Insider, January 7, 2019
23andMe Will Add Weight-Loss Advice to Its DNA-Testing Services
KV Brown, Bloomberg, January 8, 2019
Would a DNA test help you stick to your diet?
SE Richards, LA Times, December 29, 2018
More information on this topic
Big Data
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Big Data to Knowledge Program Resources
NIH, 2019
Can Big Data Deliver on Its Promises?Leaps but Not Bounds
ID Peltan et al, JAMA Network Open, December 2018
Data mining for health: staking out the ethical territory of digital phenotyping
N Martinez-Martin etal, Nature Digital Medicine, December 2018
Social Determinants of Health in the Digital Age: Determining the Source Code for Nurture.
Abnousi Freddy et al. JAMA 2018 Dec
More information on this topic
Hereditary Hemochromatosis
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Common gene disorder causes serious stealth disease, but could be easily treated
UK Biobank, January 17,. 2019
Common conditions associated with hereditary haemochromatosis genetic variants: cohort study in UK Biobank
LC Pilling et al, BMJ, January 16, 2019
Higher age at diagnosis of hemochromatosis is the strongest predictor of the occurrence of hepatocellular carcinoma in the Swiss hemochromatosis cohort: A prospective longitudinal observational study.
Nowak Albina et al. Medicine 2018 Oct 97(42) e12886
Hereditary Hemochromatosis
Hereditary hemochromatosis is a genetic disorder that can cause severe liver disease and other health problems
More information on this topic
Cancer Genomics
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Utility of the JAX Clinical Knowledgebase in capture and assessment of complex genomic cancer data
SE Patterson et al, npj PRecision Oncology, January 15, 2019
Association of JAK2-V617F Mutations Detected by Solid Tumor Sequencing With Coexistent Myeloproliferative Neoplasms
G Riedlinger et al, JAMA Oncology, January 3, 2019
Solicitation for NCI Genomic Characterization Centers
NCI, December 2018
Cancer researchers seek to harness mysterious DNA super-enhancers
H Ledford, Nature, December 5, 2018
More information on this topic
Immunotherapy
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Highly mutated cancers respond better to immune therapy-The complex tests that gauge mutation levels will pose a challenge in the clinic.
H Ledford, Nature, January 15, 2016
Immune Checkpoint Inhibitors
NCI Video, 2018
High and low mutational burden tumors versus immunologically hot and cold tumors and response to immune checkpoint inhibitors
SM Vareki, Genome Biology, December 27, 2018
Genomics of response to immune checkpoint therapies for cancer: implications for precision medicine
JR Conway et al, Genome Medicine, November 30, 2018
More information on this topic
Data Sharing
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The Open Data Explosion
V Callier, The Scientist, January 2`019
BRCA Exchange: Data sharing for the Benefit of Science and Medicine
Global Alliance for Genetics and Health, 2019
Protecting Participants, Empowering Researchers: Providing Access to Genomic Summary Results
ED Green et al, NHGRI, November 1, 2018
Variant data sharing by clinical laboratories through public databases: consent, privacy and further contact for research policies
M Shabani et al,. Genetics in Medicine, October 8, 2018
More information on this topic
Real Stories
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One Couples Tireless Crusade to Stop a Genetic Killer
Wired, January 14, 2019
A fathers fight to help his sons and fix clinical trials
D Adam, Nature, January 9, 2019
Reflecting on a New Year
S Seim, the FH Foundation, January 2019
Our child received a devastating diagnosis before she was born. We decided to protect her
A Chang, Stat News, January 7, 2019
More information on this topic
Content Summary
- CDC Information (1010)
- CDC Genomics Publications (2191)
- Epidemiologic Studies (139510)
- Translation/Implementation Studies (7282)
- Evidence Synthesis (1000)
- Guidelines (619)
- Tier Table (180)
- State Public Health Genomics Programs (275)
- Reviews/Commentaries (8899)
- Tools/Methods (566)
- Ethical/Legal and Social Issues (ELSI) (862)
- Advanced Molecular Detection Clips (10402)
- Grants Supporting Publications (52557)
About PHGKB
The CDC Public Health Genomics Knowledge Base is an online, continuously updated, searchable database that addresses translation of genomic discoveries into improved health care and disease prevention.
Read more
Citation: Yu W, et al. A knowledge base for tracking the impact of genomics on population health Genet Med.2016 Dec;18(12):1312-1314
Genomics & Health Impact Weekly Scan features emerging roles of human genomics, testing and interventions in a wide variety of noncommunicable diseases across the life span, including, birth defects, newborn screening, reproductive health, childhood diseases, cancer, chronic diseases, pharmacogenomics, family health history, guidelines and recommendations. The weekly sweep also includes news, reviews, commentaries, tools and databases.
Birth Defects and Child Health
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Chromosomal Microarray Analysis as a First-Tier Clinical Diagnostic Test in Patients With Developmental Delay/Intellectual Disability, Autism Spectrum Disorders, and Multiple Congenital Anomalies: A Prospective Multicenter Study in Korea.
Jang Woori et al. Annals of laboratory medicine 2019 May 39(3) 299-310 -
Targeted Next-Generation Sequencing of Korean Patients With Developmental Delay and/or Intellectual Disability.
Han Ji Yoon et al. Frontiers in pediatrics 2018 6391 -
Next-Generation Sequencing to Diagnose Suspected Genetic Disorders.
Li Shantao et al. The New England journal of medicine 2019 Jan 380(2) 200
Cancer
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Targeted RNA-seq successfully identifies normal and pathogenic splicing events in breast/ovarian cancer susceptibility and Lynch syndrome genes.
Brandão Rita D et al. International journal of cancer 2019 Jan -
Results of PONDx, a prospective multicenter study of the Oncotype DX ® breast cancer assay: Real-life utilization and decision impact in French clinical practice.
Curtit Elsa et al. Breast (Edinburgh, Scotland) 2019 Jan 4439-45 -
Mutational profile of colorectal cancer lung metastases and paired primary tumors by targeted next generation sequencing: implications on clinical outcome after surgery.
Schweiger Thomas et al. Journal of thoracic disease 2018 Nov 10(11) 6147-6157 -
Are BRCA1 and BRCA2 gene mutation patients underscreened for pancreatic adenocarcinoma?
Roch Alexandra M et al. Journal of surgical oncology 2019 Jan -
Three inflammation-related genes could predict risk in prognosis and metastasis of patients with breast cancer.
Zhao Shuangtao et al. Cancer medicine 2019 Jan -
Predicting EGFR Mutation Status in Lung Adenocarcinoma on CT Image Using Deep Learning.
Wang Shuo et al. The European respiratory journal 2019 Jan -
Effect of a Collaboration Between a Health Plan, Oncology Practice, and Comprehensive Genomic Profiling Company from the Payer Perspective.
Reitsma Mitchell et al. Journal of managed care & specialty pharmacy 2019 Jan 1-10 -
The association between non-breast and ovary cancers and BRCA mutation in first- and second-degree relatives of high-risk breast cancer patients: a large-scale study of Koreans.
Kim Hakyoung et al. Hereditary cancer in clinical practice 2019 171 -
Epigenomic promoter alterations predict for benefit from immune checkpoint inhibition in metastatic gastric cancer.
Sundar R et al. Annals of oncology : official journal of the European Society for Medical Oncology 2019 Jan
Chronic Disease
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Efficacy of Integrating a Novel 16-Gene Biomarker Panel and Intelligence Classifiers for Differential Diagnosis of Rheumatoid Arthritis and Osteoarthritis.
Long Nguyen Phuoc et al. Journal of clinical medicine 2019 Jan 8(1) -
Change in Prevalence of Family History During Long-term Follow-up of Pediatric-onset Inflammatory Bowel Disease Patients.
Capone Kristin et al. Journal of pediatric gastroenterology and nutrition 2019 Jan
Ethics/Policy/Law
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Return of individual genomic research results: are laws and policies keeping step?
Thorogood Adrian et al. European journal of human genetics : EJHG 2019 Jan
Practice
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Role and practice evolution for genetic counseling in the genomic era: The experience of Australian and UK genetics practitioners.
Dwarte Tanya et al. Journal of genetic counseling 2018 Dec -
Patients' perspectives of variants of uncertain significance and strategies for uncertainty management.
Makhnoon Sukh et al. Journal of genetic counseling 2019 Jan -
Genetic testing is the future of healthcare, but many experts say companies like 23andMe are doing more harm than good
E Brodwin, Business Insider, January 7, 2019 -
Core competencies in genetics for healthcare professionals: results from a literature review and a Delphi method.
Tognetto Alessia et al. BMC medical education 2019 Jan 19(1) 19 -
Genetic counselor workflow study: The times are they a-changin'?
Attard Courtney A et al. Journal of genetic counseling 2018 Dec -
Use of generic medicines in Latvia: awareness, opinions and experiences of the population.
Salmane Kulikovska Ieva et al. Journal of pharmaceutical policy and practice 2019 121
Newborn Screening
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Recognizing 50 Years of Innovative Newborn Screening in North Carolina.
Turner Lou F et al. North Carolina medical journal 80(1) 45-48 -
Lessons Learned from Newborn Screening in Pilot Studies.
Taylor Jennifer L et al. North Carolina medical journal 80(1) 54-58 -
What is Newborn Screening?
Powell Cynthia M et al. North Carolina medical journal 80(1) 32-36 -
Newborn Screening Policy Decisions: Adding Conditions.
Shone Scott M et al. North Carolina medical journal 80(1) 42-44 -
The Role of the Genetic Counselor in Newborn Screening.
Marcus Gail et al. North Carolina medical journal 80(1) 39-40 -
The Future of Newborn Screening: Why and How Partnerships Will Be Needed for Success.
Bailey Donald B et al. North Carolina medical journal 80(1) 28-31 -
Value of genetic analysis for confirming inborn errors of metabolism detected through the Spanish neonatal screening program.
Navarrete Rosa et al. European journal of human genetics : EJHG 2019 Jan
Pharmacogenomics
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Online decision support for persons having a genetic predisposition to cancer and their partners during reproductive decision-making.
Reumkens Kelly et al. Journal of genetic counseling 2018 Dec -
Patient decision-making and the role of the prenatal genetic counselor: An exploratory study.
Salema Diane et al. Journal of genetic counseling 2018 Dec -
Impact of preimplantation genetic testing for aneuploidy on obstetrical practice.
Chan Yiu-Man et al. Current opinion in obstetrics & gynecology 2019 Jan -
Perinatal follow-up of children born after preimplantation genetic diagnosis between 1995 and 2014.
Heijligers Malou et al. Journal of assisted reproduction and genetics 2018 Nov 35(11) 1995-2002 -
Whole exome sequencing for prenatal diagnosis in cases with fetal anomalies: Criteria to improve diagnostic yield.
Yadava Stacy M et al. Journal of genetic counseling 2018 Dec -
The value of non-invasive prenatal testing: preferences of Canadian pregnant women, their partners, and health professionals regarding NIPT use and access.
Birko Stanislav et al. BMC pregnancy and childbirth 2019 Jan 19(1) 22 -
Noninvasive screening by cell-free DNA for 22q11.2 deletion: Benefits, limitations, and challenges.
Grati Francesca Romana et al. Prenatal diagnosis 2019 Jan
Reproductive Health
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The Effect of Polymorphism in UGT1A4 on Clinical Outcomes of Adjuvant Tamoxifen Therapy for Patients With Breast Cancer in China.
Lan Bo et al. Clinical breast cancer 2018 Dec -
Validation of a clinical pharmacogenetic model to predict methotrexate nonresponse in rheumatoid arthritis patients.
Eektimmerman Frank et al. Pharmacogenomics 2019 Jan -
Tolerance-based capecitabine dose escalation after DPYD genotype-guided dosing in heterozygote DPYD variant carriers: a single-center observational study.
Kleinjan Jan P et al. Anti-cancer drugs 2019 Jan
News/ Reviews/Comments
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Public Comment on Draft Recommendation Statement and Draft Evidence Review: Medication Use to Reduce Risk of Breast Cancer
U.S.Preventive Services Task Force, January 2019
Eventr
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Telegenetics and Its Implementation in Cancer Genetic Counseling
January 30, 2019, 12:00-1:00pm EST
Advanced Molecular Detection Clips (AMD Clips) are selected weekly from a variety of sources, including PubMed, journal tables of contents, and online media. Special emphasis is given to the use of next-generation genetic sequencing in infectious disease public health surveillance, investigation, and development of new diagnostics and interventions. The collection is not comprehensive but aims to capture highlights, while surveying a wide range of topics. CDC-authored articles are flagged. Items marked I&E address aspects of implementation or evaluation in clinical or public health practice.
- News
- Events / Training / Web Resources
- Policy
- Concepts / Comments
- Methods / Tools
- Evolution / Ecology / Populations
- Pathogenicity / Antimicrobial Resistance
- Detection / Diagnosis
- Epidemiology / Outbreaks / Transmission
- Antimicrobials / Vaccines / Interventions
- Host-Microbe Interactions
NEWS
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DNA Extraction Remains Bottleneck for Long-Read Techs But Solutions Begin to Emerge
Karow J. GenomeWeb, Jan 14, 2019. -
How elusive can a malaria vaccine be?
Pance A. Nat Rev Microbiol, Jan 9, 2019. -
The bacteria in your gut may reveal your true age
Mullin E. Science, Jan 11, 2019.
EVENTS / TRAINING / WEB RESOURCES
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Fundamentals of Data Visualization
(online book) Wilke CO. 2018. -
Applied Bioinformatics and Public Health Microbiology
(course) Wellcome Genome Campus, UK, June 5-7, 2019.
POLICY
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Science with borders: A debate over genetic sequences and national rights threatens to inhibit research
Branswell H. STAT, Jan 14, 2019.
CONCEPTS / COMMENTS
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Integration of microbiology, molecular pathology, and epidemiology: a new paradigm to explore the pathogenesis of microbiome-driven neoplasms.
Hamada Tsuyoshi et al. The Journal of pathology 2019 Jan -
Invited Commentary: Improving accessibility of the Human Microbiome Project data through integration with R/Bioconductor.
Griffith Jocelyn C et al. American journal of epidemiology 2019 Jan
METHODS / TOOLS
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Improved DNA extraction technique from clot for the diagnosis of Chagas disease.
Mayta Holger et al. PLoS neglected tropical diseases 2019 Jan (1) e0007024 -
Impact of inter- and intra-individual variation, sample storage and sampling fraction on human stool microbial community profiles.
Yeoh Yun Kit et al. PeerJ 2019 e6172 -
Identifying accurate metagenome and amplicon software via a meta-analysis of sequence to taxonomy benchmarking studies.
Gardner Paul P et al. PeerJ 2019 e6160 -
HMP16SData: Efficient Access to the Human Microbiome Project through Bioconductor.
Schiffer Lucas et al. American journal of epidemiology 2019 Jan -
Shared genome analyses of notable listeriosis outbreaks, highlighting the critical importance of epidemiological evidence, input datasets and interpretation criteria.
Reimer Aleisha et al. Microbial genomics 2019 Jan -
Tracking the popularity and outcomes of all bioRxiv preprints
Abdill RJ, Blekhman R. bioRxiv, Jan 13, 2019.
EVOLUTION / ECOLOGY / POPULATIONS
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Limited contribution of non-intensive chicken farming to ESBL-producing Escherichia coli colonization in humans in Vietnam: an epidemiological and genomic analysis.
Nguyen Vinh Trung et al. The Journal of antimicrobial chemotherapy 2019 Jan -
Where the plasmids roam: large-scale sequence analysis reveals plasmids with large host ranges.
Brooks Lauren Elisabeth et al. Microbial genomics 2019 Jan -
Whole genome sequencing reveals Trans-European spread of an epidemic Neisseria meningitidis serogroup W clone.
Taha Muhamed-Kheir et al. Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases 2019 Jan -
Complete Genome Sequences of Four Salmonella enterica Strains (Including Those of Serotypes Montevideo, Mbandaka, and Lubbock) Isolated from Peripheral Lymph Nodes of Healthy Cattle.
Bugarel Marie et al. Microbiology resource announcements 2019 Jan (2)
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Genome Sequences of Penicillin-Resistant Bacillus anthracis Strains.
Gargis Amy S et al. Microbiology resource announcements 2019 Jan (2)
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Molecular Detection and Phylogenetic Analysis of Anaplasma phagocytophilum in Horses in Korea.
Seo Min-Goo et al. The Korean journal of parasitology 2018 Dec (6) 559-565 -
A cross-sectional screening by next-generation sequencing reveals Rickettsia, Coxiella, Francisella, Borrelia, Babesia, Theileria and Hemolivia species in ticks from Anatolia.
Brinkmann Annika et al. Parasites & vectors 2019 Jan (1) 26 -
Longitudinal study for enterovirus A71 and coxsackievirus A16 genotype/subgenotype replacements in hand, foot and mouth disease patients in Thailand, 2000-2017.
Noisumdaeng Pirom et al. International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases 2019 Jan -
Emergence of new genotypes and lineages of dengue viruses during the 2012-15 epidemics in southern India.
Ahamed Syed Fazil et al. International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases 2019 Jan -
Occurrence of noroviruses in recycled water and sewage sludge: emergence of recombinant norovirus strains.
Kittigul L et al. Journal of applied microbiology 2019 Jan -
Phylogeographic analysis of human influenza A and B viruses in Myanmar, 2010-2015.
Htwe Khin Thu Zar et al. PloS one 2019 (1) e0210550 -
Monkeypox virus phylogenetic similarities between a human case detected in Cameroon in 2018 and the 2017-2018 outbreak in Nigeria.
Sadeuh-Mba Serge Alain et al. Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases 2019 Jan -
New strains of Japanese encephalitis virus circulating in Shanghai, China after a ten-year hiatus in local mosquito surveillance.
Fang Yuan et al. Parasites & vectors 2019 Jan (1) 22 -
The reemergence of human rabies and emergence of an Indian subcontinent lineage in Tibet, China.
Tao Xiao-Yan et al. PLoS neglected tropical diseases 2019 Jan (1) e0007036
PATHOGENICITY / ANTIMICROBIAL RESISTANCE
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Sequential evolution of virulence and resistance during clonal spread of community-acquired methicillin-resistant Staphylococcus aureus .
Copin Richard et al. Proceedings of the National Academy of Sciences of the United States of America 2019 Jan -
Regional outbreak of community-associated methicillin-resistant Staphylococcus aureus ST834 in Japanese children.
Uehara Yuki et al. BMC infectious diseases 2019 Jan (1) 35 -
Development of New Tools to Detect Colistin-Resistance among Enterobacteriaceae Strains.
Bardet Lucie et al. The Canadian journal of infectious diseases & medical microbiology = Journal canadien des maladies infectieuses et de la microbiologie medicale 2018 3095249 -
Dissemination and characterization of extended spectrum β-lactamase, AmpC β-lactamase and metallo β-lactamase producing Escherichia coli from livestock and poultry in Northeastern India: A molecular surveillance approach.
Tewari Rituparna et al. Journal of global antimicrobial resistance 2019 Jan -
Adding function to the genome of African Salmonella Typhimurium ST313 strain D23580.
Canals Rocío et al. PLoS biology 2019 Jan (1) e3000059 -
Molecular epidemiology and expression of capsular polysaccharides in Staphylococcus aureus clinical isolates in the United States.
Mohamed Naglaa et al. PloS one 2019 (1) e0208356 -
Genome-wide association analyses of invasive pneumococcal isolates identify a missense bacterial mutation associated with meningitis.
Li Yuan et al. Nature communications 2019 Jan (1) 178
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Analysis of antifungal resistance genes in Candida albicans and Candida glabrata using next generation sequencing.
Spettel Kathrin et al. PloS one 2019 (1) e0210397
DETECTION / DIAGNOSIS
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Determining the Cause of Death Among Children Hospitalized With Respiratory Illness in Kenya: Protocol for Pediatric Respiratory Etiology Surveillance Study (PRESS).
Njuguna Henry N et al. JMIR research protocols 2019 Jan (1) e10854
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Metagenomic analysis of viruses in toilet waste from long distance flights-A new procedure for global infectious disease surveillance.
Hjelmsø Mathis Hjort et al. PloS one 2019 (1) e0210368 -
Analysis of serum hepatitis B virus RNA levels in a multiethnic cohort of pregnant chronic hepatitis B carriers.
Patel Nishi H et al. Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology 2019 Jan 42-47 -
Emergence of Madariaga virus as a cause of acute febrile illness in children, Haiti, 2015-2016.
Lednicky John A et al. PLoS neglected tropical diseases 2019 Jan (1) e0006972
EPIDEMIOLOGY / OUTBREAKS / TRANSMISSION
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Nosocomial outbreak of esbl-producing enterobacter cloacae among cardio-thoracic surgical patients: causes and consequences.
Noël A et al. The Journal of hospital infection 2019 Jan -
Multi-step genomic dissection of a suspected intra-hospital Helicobacter cinaedi outbreak.
Gotoh Yasuhiro et al. Microbial genomics 2018 Dec (12) -
An outbreak of vanA vancomycin-resistant Enterococcus faecium in a hospital with endemic vanB VRE.
Hughes Angus et al. Infection, disease & health 2019 Jan -
Genomic approaches used to investigate an atypical outbreak of Salmonella Adjame.
Chattaway Marie Anne et al. Microbial genomics 2019 Jan -
Whole genome sequencing suggests transmission of Corynebacterium diphtheriae -caused cutaneous diphtheria in two siblings, Germany, 2018.
Berger Anja et al. Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin 2019 Jan (2) -
Unmasking leading to a healthcare worker Mycobacterium tuberculosis transmission.
Holden K L et al. The Journal of hospital infection 2018 Dec (4) e226-e232 -
Modeling suggests that microliter volumes of contaminated blood caused an outbreak of hepatitis C during computerized tomography.
Shteyer Eyal et al. PloS one 2019 (1) e0210173 -
Epidemiological aspects of the persistent transmission of rabies during an outbreak (2010 - 2017) in Harare, Zimbabwe.
Coetzer Andre et al. PloS one 2019 (1) e0210018
ANTIMICROBIALS / VACCINES / INTERVENTIONS
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Impact of single room contact precautions on hospital-acquisition and transmission of multidrug-resistant Escherichia coli: a prospective multicentre cohort-study in haematological and oncological wards.
Biehl Lena M et al. Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases 2019 Jan
HOST-MICROBE INTERACTIONS
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The effect of antimicrobial drug use on the composition of the genitourinary microbiota in an elderly population.
Mulder M et al. BMC microbiology 2019 Jan (1) 9 -
Intestinal parasitic infection alters bacterial gut microbiota in children.
Toro-Londono Miguel A et al. PeerJ 2019 e6200 -
Comparison of the salivary and dentinal microbiome of children with severe-early childhood caries to the salivary microbiome of caries-free children.
Hurley Eimear et al. BMC oral health 2019 Jan (1) 13 -
Role of colonic microbiota in the pathogenesis of ulcerative colitis.
Pei Ling-Yan et al. BMC gastroenterology 2019 Jan (1) 10 -
Genetic variation/evolution and differential host responses resulting from in-patient adaptation of Mycobacterium avium .
Kannan N et al. Infection and immunity 2019 Jan -
Association study between CCR2-CCR5 genes polymorphisms and chronic Chagas heart disease in Wichi and in admixed populations from Argentina.
Juiz Natalia Anahí et al. PLoS neglected tropical diseases 2019 Jan (1) e0007033
indicates that at least one CDC-affiliated author; indicates that the article addresses aspects of implementation or evaluation in clinical or public health practice.
Site Citation
- Yu W, Gwinn M, Dotson WD, Green RF, Clyne M, Wulf A, Bowen S, Kolor K, Khoury MJ. A knowledge base for tracking the impact of genomics on population health Genet Med. 2016 Jun 9. doi: 10.1038/gim.2016.63. [Epub ahead of print]
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