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Last Posted: Nov-15-2019 12:14:47

Many Adults with Familial Hypercholesterolemia Are Not Meeting Goal LDL-Cholesterol Level
RF Green et al, CDC Blog Post, November 15, 2019 Brand

Among patients in the CASCADE FH registry, 73.7% were on statins, Even among the study population, which was selected from specialty clinics and likely receiving more aggressive cholesterol-lowering therapies than the general FH population, only 48% achieved LDL-cholesterol <100 mg/dL, and only 22% reached LDL-cholesterol <70 mg/dL.

Toward Risk-Stratified Breast Cancer Screening: Considerations for Changes in Screening Guidelines
GL Gierach et al, JAMA Oncology, November 14, 2019

Improved strategies for risk-stratified breast cancer screening should take into account not only family history, but also existing & emerging prediction tools (eg genetic risk scores) for breast cancer and its biologically heterogeneous subtypes.

Biggest Threats and Data- 2019 AR Threats Report
CDC, November 2019 Brand

More than 2.8 million antibiotic-resistant infections occur in the U.S. each year, and more than 35,000 people die as a result. In addition, 223,900 cases of Clostridioides difficile occurred in 2017 and at least 12,800 people died.

Item of Interest: Now Available: NIH Research Plan on Fragile X and Associated Conditions
NIH, November 2019 Brand

The overarching goal of the plan is to develop a more comprehensive picture of the FMR1 gene and how it affects health. The plan also identifies activities that can enhance existing efforts and explore new avenues for improving the health of individuals affected by FMR1-related conditions.

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Disclaimer: Articles listed in the Public Health Genomics and Precision Health Knowledge Base are selected by the CDC Office of Public Health Genomics to provide current awareness of the literature and news. Inclusion in the update does not necessarily represent the views of the Centers for Disease Control and Prevention nor does it imply endorsement of the article's methods or findings. CDC and DHHS assume no responsibility for the factual accuracy of the items presented. The selection, omission, or content of items does not imply any endorsement or other position taken by CDC or DHHS. Opinion, findings and conclusions expressed by the original authors of items included in the update, or persons quoted therein, are strictly their own and are in no way meant to represent the opinion or views of CDC or DHHS. References to publications, news sources, and non-CDC Websites are provided solely for informational purposes and do not imply endorsement by CDC or DHHS.

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