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Health Equity PHGKB

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Last Posted: Mar 02, 2021
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World Birth Defects Day, March 3, 2021
CDC, March 2021

March 3 is World Birth Defects Day. Join us to raise awareness of birth defects, their causes, and their impact around the world! Our theme is “Many birth defects, one voice.” Every year, about 3-6% of infants worldwide are born with a serious birth defect. This means that life-altering conditions like spina bifida and congenital heart defects affect millions of babies regardless of where they are born, their socioeconomic status, or their race or ethnicity.

Racial and ethnic differences in COVID-19 vaccine hesitancy and uptake
LH Nguyen et al, MEDRXIV, February 28, 2021

We performed a cohort study of participants in the smartphone-based COVID Symptom Study (March 24, 2020-February 16, 2021). In the U.S. (n=87,388), compared to White non-Hispanic participants, the multivariable ORs of vaccine hesitancy were 3.15 (95% CI: 2.86 to 3.47) for Black participants, 1.42 (1.28 to 1.58) for Hispanic participants, 1.34 (1.18 to 1.52) for Asian participants, and 2.02 (1.70 to 2.39) for participants reporting more than one race/other.

Non-communicable diseases pandemic and precision medicine: Is Africa ready?
T Chikowore et al, Ebiomedicine, February 2021

Africa has been lagging behind in genetic research, a key component of the precision medicine initiative. A number of genomic research initiatives which could lead to translational genomics are emerging on the African continent. This review evaluates the advances of genetic studies for cancer, hypertension, type 2 diabetes and body mass index (BMI) in Africa.

Covid-19 vaccine hesitancy among ethnic minority groups
MS Razai et al, BMJ, February 26, 2021

The most common reasons for hesitancy are concerns about side effects and the long term effects on health, and lack of trust in vaccines, particularly among black respondents. Some have capitalized on these concerns to spread misinformation, adding to the historical mistrust of government and public health bodies that runs deep in some ethnic minority groups.


news Latest News and Publications
Equity and Artificial Intelligence in Surgical Care External Web Site Icon
CN Johnson-Mann et al, JAMA Surgery, February 2021
Johnson & Johnson vaccine deepens concerns over racial and geographic inequities- Decisions to send it to harder-to-reach communities make practical sense, but could drive perceptions of a two-tiered system. External Web Site Icon
IS Becker, the Washington Post, March 1, 2021
Predictably unequal: understanding and addressing concerns that algorithmic clinical prediction may increase health disparities. External Web Site Icon
Paulus Jessica K et al. NPJ digital medicine 2020 Jul 3(1) 99
Evaluating the promise of inclusion of African ancestry populations in genomics. External Web Site Icon
Bentley Amy R et al. NPJ genomic medicine 2020 Feb 5(1) 5
The Utility of Genetic Risk Score to Improve Performance of FRAX for Fracture Prediction in US Postmenopausal Women. External Web Site Icon
Xiao Xiangxue et al. Calcified tissue international 2021 Feb
Characteristics and Factors Associated with COVID-19 Infection, Hospitalization, and Mortality Across Race and Ethnicity External Web Site Icon
CL Dai et al, MEDRXIV, February 13, 2021
Explaining ethnic disparities in COVID-19 mortality: population-based, prospective cohort study External Web Site Icon
GD Batty et al, MEDRXIV, February 11, 2021
Explaining ethnicity disparities in COVID-19 mortality: population-based, prospective cohort study External Web Site Icon
GD Batty et al, MEDRXIV, February 8, 2021
Challenges of Genomic Testing for Hereditary Breast and Ovarian Cancers. External Web Site Icon
McAlarnen Lindsey et al. The application of clinical genetics 2021 141-9
Polygenic risk scores in the clinic: new perspectives needed on familiar ethical issues. External Web Site Icon
Lewis Anna C F et al. Genome medicine 2021 Jan 13(1) 14

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About Health Equity PHGKB

Health Equity PHGKB is an online, continuously updated, searchable database of genomics and precision health information and publications relevant to health equity...more

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Disclaimer: Articles listed in the Public Health Knowledge Base are selected by the CDC Office of Public Health Genomics to provide current awareness of the literature and news. Inclusion in the update does not necessarily represent the views of the Centers for Disease Control and Prevention nor does it imply endorsement of the article's methods or findings. CDC and DHHS assume no responsibility for the factual accuracy of the items presented. The selection, omission, or content of items does not imply any endorsement or other position taken by CDC or DHHS. Opinion, findings and conclusions expressed by the original authors of items included in the update, or persons quoted therein, are strictly their own and are in no way meant to represent the opinion or views of CDC or DHHS. References to publications, news sources, and non-CDC Websites are provided solely for informational purposes and do not imply endorsement by CDC or DHHS.

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