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Health Equity PHGKB

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Last Posted: Sep 21, 2023
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Biomarker-Directed Therapy in Black and White Men With Metastatic Castration-Resistant Prostate Cancer.
Clara Hwang et al. JAMA Netw Open 2023 9 (9) e2334208

From the abstract: "Do disparities exist in the application of precision medicine for Black and White men with metastatic prostate cancer? In this cohort study of 962 men with metastatic castration-resistant prostate cancer, mismatch repair deficiency or microsatellite instability-high was significantly more frequent in Black men than White men. However, Black men were significantly less likely to receive molecularly matched targeted therapy than White men. These findings suggest that although precision medicine in metastatic prostate cancer has become more common, opportunities remain to improve access to precision medicine to benefit Black men with prostate cancer. "

Unequal global implementation of genomic newborn screening.
Ahmad N Abou Tayoun et al. Nat Rev Genet 2023 9

From the abstract: "Studies of genomic newborn screening are highly skewed towards populations in high-income countries. The evidence generated by these studies will be similarly biased and is likely to lead to disparate global implementation. Studies inclusive of historically under-represented populations are needed for equitable global access to genomic newborn screening. "

Future Forecasting for Research and Practice in Genetic Literacy
KA Kapingst, Public Health Genomics, September 13, 2023

From the abstract: "Available evidence highlights important gaps in genetic literacy throughout the population, limiting the potential use of these technologies to improve the health of individuals, their families, and their communities. Effective communication approaches are needed to meet the needs of individuals with varying levels of genetic literacy and from different communities. To achieve this goal, this piece highlights essential areas of research and practice in genetic literacy that are needed to inform public health translation of genomic discoveries. "

Considerations for addressing bias in artificial intelligence for health equity
Abramoff MD, et al, NPJ Digital Medicine, September 12, 2023

From the abstract: "Health equity is a primary goal of healthcare stakeholders: patients and their advocacy groups, clinicians, other providers and their professional societies, bioethicists, payors and value based care organizations, regulatory agencies, legislators, and creators of artificial intelligence/machine learning (AI/ML)-enabled medical devices. Lack of equitable access to diagnosis and treatment may be improved through new digital health technologies, especially AI/ML, but these may also exacerbate disparities, depending on how bias is addressed. "


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Racial and ethnic differences in perceptions of germline or somatic DNA sequencing among patients with advanced prostate, urothelial, or kidney cancer. External Web Site Icon
Cristiane Decat Bergerot et al. J Genet Couns 2023
Using Artificial Intelligence Algorithms to Predict the Overall Survival of Hemodialysis Patients during the COVID-19 Pandemic: A Prospective Cohort Study. External Web Site Icon
Tang Shao-Yu, et al. Journal of the Chinese Medical Association : JCMA 2023 0 0.
Unraveling the Ethical Enigma: Artificial Intelligence in Healthcare. External Web Site Icon
Madhan Jeyaraman et al. Cureus 2023 15(8) e43262
Factors influencing genetic screening enrollment among a diverse, community-ascertained cohort. External Web Site Icon
Nandana D Rao et al. Public Health Genomics 2023
Extending an Antiracism Lens to the Implementation of Precision Public Health Interventions. External Web Site Icon
Caitlin G Allen et al. Am J Public Health 2023 e1-e9
Reduced COVID-19 morbidity and mortality in hemodialysis patients across the various Omicron sublineages-A retrospective analysis. External Web Site Icon
Schuller Max, et al. Frontiers in public health 2023 0 0. 1218188
Advancing AI in Healthcare: A Comprehensive Review of Best Practices. External Web Site Icon
Sergei Polevikov et al. Clin Chim Acta 2023 117519
New York State, New York City, New Jersey, Puerto Rico, and the US Virgin Islands' Health Department Experiences Promoting Health Equity During the Initial COVID-19 Omicron Variant Period, 2021-2022. External Web Site Icon
Cox Heidi, et al. Health security 2023 0 0.
Using machine learning to identify patient characteristics to predict mortality of in-patients with COVID-19 in south Florida. External Web Site Icon
Datta Debarshi, et al. Frontiers in digital health 2023 0 0. 1193467
Genetic counseling in sickle cell disease: Insights from the Indian tribal population. External Web Site Icon
Pooja Aggarwal et al. J Community Genet 2023 8

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About Health Equity PHGKB

Health Equity PHGKB is an online, continuously updated, searchable database of genomics and precision health information and publications relevant to health equity...more

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Disclaimer: Articles listed in the Public Health Knowledge Base are selected by the CDC Office of Public Health Genomics to provide current awareness of the literature and news. Inclusion in the update does not necessarily represent the views of the Centers for Disease Control and Prevention nor does it imply endorsement of the article's methods or findings. CDC and DHHS assume no responsibility for the factual accuracy of the items presented. The selection, omission, or content of items does not imply any endorsement or other position taken by CDC or DHHS. Opinion, findings and conclusions expressed by the original authors of items included in the update, or persons quoted therein, are strictly their own and are in no way meant to represent the opinion or views of CDC or DHHS. References to publications, news sources, and non-CDC Websites are provided solely for informational purposes and do not imply endorsement by CDC or DHHS.

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