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Implementation Science PHGKB

Specific PHGKB|Implementation Science PHGKB|Public Health Genomics and Precision Health Knowledge Base (PHGKB)
Effective August 1, 2024, this database was discontinued. All content will remain searchable and be preserved online for historical purposes only until 2029.

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Training Institute for Dissemination and Implementation Research in Genomics and Precision Public Health (TIDIR-GPPH) Facilitated Course

From the website: "The Training Institute for Dissemination and Implementation Research in Genomics and Precision Public Health (TIDIR-GPPH) Facilitated Course is being offered in 2024 and is open to all current ORISE fellows and mentors! The course is intended to provide participants with a thorough grounding in conducting dissemination and implementation (D&I) research with a specific focus on genomics and precision public health. TIDIR-GPPH will be a hybrid course including training through open access modules with assigned reading material and office hours and culminating with a 2-day in-person event (September 5-6, 2024)."

A new agenda for implementing population genomic screening

"Nearly a decade into the proliferation of population genomic screening programs, it is clear that such programs provide benefit in certain contexts. Determining whether these programs provide net positive outcomes across diverse populations, however, will require a significant shift in approach and scale. This shift can be modeled on a precision health research agenda that capitalizes on pragmatic and implementation science methods, learning health system principles, and stakeholder engagement. Acknowledging that research and clinical implementation must coexist will help us realize the promise of population genomic screening."

Implementation research: an approach to overcoming the know-do gap

From the article: " Many people who could benefit from evidence-based treatments do not receive them; a circumstance that is sometimes referred to as the know-do gap. We know the interventions that can be beneficial, but we do not know how to do those interventions in real-world settings. The gap can be particularly large if influenced adversely by social determinants of health. Implementation research seeks to produce evidence to reduce the know-do gap."

Family cascade screening for equitable identification of familial hypercholesterolemia: study protocol for a hybrid effectiveness-implementation type III randomized controlled trial

From the abstract: " Familial hypercholesterolemia (FH) is a heritable disorder affecting 1.3 million individuals in the USA. Eighty percent of people with FH are undiagnosed, particularly minoritized populations including Black or African American people, Asian or Asian American people, and women across racial groups. Family cascade screening is an evidence-based practice that can increase diagnosis and improve health outcomes but is rarely implemented in routine practice, representing an important care gap. In pilot work, we leveraged best practices from behavioral economics and implementation science—including mixed-methods contextual inquiry with clinicians, patients, and health system constituents—to co-design two patient-facing implementation strategies to address this care gap..."


news Latest News and Publications
Implementing digital respiratory technologies for people with respiratory conditions: A protocol for a scoping review. External Web Site Icon
Hui Chi Yan, et al. PloS one 2024 0 0. (12) e0314914
Digital health implementation in Australia: A scientometric review of the research. External Web Site Icon
Krahe Michelle A, et al. Digital health 2024 0 0. 20552076241297729
The recent history and near future of digital health in the field of behavioral medicine: an update on progress from 2019 to 2024. External Web Site Icon
Arigo Danielle, et al. Journal of behavioral medicine 2024 0 0.
Factors influencing implementation of digital cardiac rehabilitation: A qualitative analysis of health workers perspectives. External Web Site Icon
Gibson Irene, et al. HRB open research 2024 0 0. 50
Telehealth for Rare Disease Care, Research, and Education Across the Globe: A Review of the Literature by the IRDiRC Telehealth Task Force. External Web Site Icon
Chen Faye H, et al. European journal of medical genetics 2024 0 0. 104977
Application of implementation science for improving the utilization of an international clinical practice guidance on familial hypercholesterolemia. External Web Site Icon
Laney K Jones et al. J Clin Lipidol 2024
Pharmacogenetic testing in primary care could bolster depression treatment: A value proposition. External Web Site Icon
Nina R Sperber et al. Clin Transl Sci 2024 17(6) e13837
Implementation of AZD7442 (Tixagevimab/Cilgavimab) COVID-19 Pre-exposure Prophylaxis (PrEP) in the Largest Health Maintenance Organization in Israel: Real-world Uptake and Sociodemographic and Clinical Characteristics Across Immunocompromised Patient Groups. External Web Site Icon
Hayek Samah, et al. Infectious diseases and therapy 2024 0 0.
Factors impacting the adoption of big data in healthcare: A systematic literature review. External Web Site Icon
Abeer Saleh Al Teneiji et al. Int J Med Inform 2024 187105460
Applying Machine Learning Techniques to Implementation Science. External Web Site Icon
Nathalie Huguet et al. Online J Public Health Inform 2024 16e50201

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About Implementation Science PHGKB

Implementation Science PHGKB is an online, continuously updated, searchable database of information and publications relevant to the role of implementation science to accelerate the translation of genomics and precision health applications into practice and programs. The ultimate success of these applications will depend on the incorporation of implementation science tools and methods in research. This research is relevant at the global, national, state, community and health systems level.

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Disclaimer: Articles listed in the Public Health Knowledge Base are selected by Public Health Genomics Branch to provide current awareness of the literature and news. Inclusion in the update does not necessarily represent the views of the Centers for Disease Control and Prevention nor does it imply endorsement of the article's methods or findings. CDC and DHHS assume no responsibility for the factual accuracy of the items presented. The selection, omission, or content of items does not imply any endorsement or other position taken by CDC or DHHS. Opinion, findings and conclusions expressed by the original authors of items included in the update, or persons quoted therein, are strictly their own and are in no way meant to represent the opinion or views of CDC or DHHS. References to publications, news sources, and non-CDC Websites are provided solely for informational purposes and do not imply endorsement by CDC or DHHS.

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