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Tier-Classified Guidelines Database


Tier Table Database|Home|PHGKB
Last data update: Feb 20, 2020. (Total: 379 Documents since 2012)
   dataset

Recent Uploaded Publications

Management of Male Breast Cancer: ASCO Guideline.
Hassett Michael J et al. Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2020 Feb JCO1903120

Organization:
Nordic Guidelines for Germline Predisposition to Myeloid Neoplasms in Adults: Recommendations for Genetic Diagnosis, Clinical Management and Follow-up.
Baliakas Panagiotis et al. HemaSphere 2019 Dec 3(6) e321

Organization:
Germline and Somatic Tumor Testing in Epithelial Ovarian Cancer: ASCO Guideline.
Konstantinopoulos Panagiotis A et al. Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2020 Jan JCO1902960

Organization:
SEOM clinical guideline on hereditary colorectal cancer (2019).
Guillén-Ponce C et al. Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico 2020 Jan

Organization:
Japan society of clinical oncology/Japanese society of medical oncology-led clinical recommendations on the diagnosis and use of tropomyosin receptor kinase inhibitors in adult and pediatric patients with neurotrophic receptor tyrosine kinase fusion-positive advanced solid tumors, cooperated by the Japanese society of pediatric hematology/oncology.
Naito Yoichi et al. International journal of clinical oncology 2020 Jan

Organization:
Guidelines for the management of hereditary colorectal cancer from the British Society of Gastroenterology (BSG)/Association of Coloproctology of Great Britain and Ireland (ACPGBI)/United Kingdom Cancer Genetics Group (UKCGG).
Monahan Kevin J et al. Gut 2019 Nov

Organization: The British Society of Gastroenterology (BSG) The Association of Coloproctology of Great Britain and Ireland (ACPGBI) The United Kingdom Cancer Genetics Group (UKCGG).
Hereditary Cancer Syndromes and Risk Assessment: ACOG COMMITTEE OPINION, Number 793.
et al. Obstetrics and gynecology 2019 Dec 134(6) e143-e149

Organization: The American College of Obstetricians and Gynecologists (ACOG)
Medication Use to Reduce Risk of Breast Cancer- US Preventive Services Task Force Recommendation Statement
USPSTF Recommendation, JAMA, September 3, 2019
Organization: The U.S. Preventive Services Task Force (USPSTF)
Recommendations from a Portuguese Expert Group for Discontinuation of Tyrosine Kinase Inhibitors in Chronic Myeloid Leukemia Patients in Clinical Practice.
Almeida Antonio et al. Acta medica portuguesa 2019 Aug 32(7-8) 550-557

Organization: Expert Panel
Molecular testing for advanced non-small cell lung cancer in Malaysia: Consensus statement from the College of Pathologists, Academy of Medicine Malaysia, the Malaysian Thoracic Society, and the Malaysian Oncological Society.
Rajadurai Pathmanathan et al. Lung cancer (Amsterdam, Netherlands) 2019 Aug 13665-73

Organization: Expert Panel
Risk Assessment, Genetic Counseling, and Genetic Testing for BRCA-Related Cancer: US Preventive Services Task Force Recommendation Statement.
US Preventive Services Task Force et al. JAMA 2019 322(7) 652-665

Organization: The U.S. Preventive Services Task Force (USPSTF)
Clinical management of cutaneous adverse events in patients on targeted anticancer therapies and immunotherapies: a national consensus statement by the Spanish Academy of Dermatology and Venereology and the Spanish Society of Medical Oncology.
Grávalos C et al. Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico 2019 May 21(5) 556-571

Organization: The Spanish Society of Medical Oncology (SSMO) The Spanish Academy of Dermatology and Venereology (ILDS)
Local Coverage Determination (LCD): Biomarker Testing for Neuroendocrine Tumors/Neoplasms (L37851)
The U.S. Centers for Medicare & Medicaid Services

Organization: The Centers for Medicare & Medicaid Services (CMS)
ACG Clinical Guideline: Hereditary Hemochromatosis.
Kowdley Kris V et al. The American journal of gastroenterology 2019 Jul

Organization: The American College of Gastroenterology (ACG)
Consensus Guidelines on Genetic` Testing for Hereditary Breast Cancer from the American Society of Breast Surgeons.
Manahan Eric R et al. Annals of surgical oncology 2019 Jul

Organization: The American Society of Breast Surgeons (ASBrS)
Endoscopic management of polyposis syndromes: European Society of Gastrointestinal Endoscopy (ESGE) guideline.
van Leerdam Monique E et al. Endoscopy 2019 Jul

Organization: The European Society of Gastrointestinal Endoscopy (ESGE)
The Society for Immunotherapy of Cancer consensus statement on immunotherapy for the treatment of squamous cell carcinoma of the head and neck (HNSCC).
Cohen Ezra E W et al. Journal for immunotherapy of cancer 2019 Jul 7(1) 184

Organization: The Society for Immunotherapy of Cancer (SITC)
Somatic gene mutation detection system (P180043)
The U.S. Food & Drug Administration
Organization: The U.S. Food and Drug Administration (FDA)
Prostrate cancer genes nucleic acid amplification test system (P100033)
The U.S. Food & Drug Administration
Organization: The U.S. Food and Drug Administration (FDA)
Cancer predisposition risk assessment system (K182784)
The U.S. Food & Drug Administration
Organization: The U.S. Food and Drug Administration (FDA)

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About

This database contains guidelines from the Genomics and Precision Health Database, sorted according to the highest evidence tier level that could be assigned to recommendations from each guideline. The sorting process is based on our previous method for classifying genomic applications (described in Clinical Pharmacology and Therapeutics, 2014), except that guideline documents rather than clinical scenarios are sorted according to evidence level. more

Recent Tier 1 Publications

Medication Use to Reduce Risk of Breast Cancer- US Preventive Services Task Force Recommendation Statement
USPSTF Recommendation, JAMA, September 3, 2019
Risk Assessment, Genetic Counseling, and Genetic Testing for BRCA-Related Cancer: US Preventive Services Task Force Recommendation Statement.
US Preventive Services Task Force et al. JAMA 2019 322(7) 652-665
Somatic gene mutation detection system (P180043)
The U.S. Food & Drug Administration
Somatic gene mutation detection system (P190004)
The U.S. Food & Drug Administration
Somatic gene mutation detection system (P190001)
The U.S. Food & Drug Administration

Top 5 Most Viewed

Cancer predisposition risk assessment system (K182784)
The U.S. Food & Drug Administration

(114 reads)
Draft Recommendation Statement and Draft Evidence Review: Risk Assessment, Genetic Counseling, and Genetic Testing for BRCA-Related Cancer
The U.S. Preventive Services Task Force

(103 reads)
Recommendations for reporting of secondary findings in clinical exome and genome sequencing, 2016 update (ACMG SF v2.0): a policy statement of the American College of Medical Genetics and Genomics.
Kalia Sarah S et al. Genetics in medicine : official journal of the American College of Medical Genetics 2016 Nov

(100 reads)
Meta-analysis and multidisciplinary consensus statement: exome sequencing is a first-tier clinical diagnostic test for individuals with neurodevelopmental disorders.
Srivastava Siddharth et al. Genetics in medicine : official journal of the American College of Medical Genetics 2019 Jun

(100 reads)
Cancer-related germline gene mutation detection system (P140020)
The U.S. Food & Drug Administration

(100 reads)

Content Statistics

  • Total Publications: 379
    • Tier 1 Publications: 89
    • Tier 2 Publications: 279
    • Tier 3 Publications: 11
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