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Last Posted: May 11, 2023
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The science events to watch for in 2023 Moon landings, mRNA vaccines and climate finance are among the developments set to shape research in the coming year.
M Naddaf et al, Nature, December 19, 2022

Following the successful deployment of mRNA vaccines during the COVID-19 pandemic, a host of them are in development. BioNTech in Mainz, Germany, is expected to initiate first-in-human trials for mRNA vaccines against malaria, tuberculosis and genital herpes in the coming weeks. BioNTech is also collaborating with Pfizer, based in New York City, to trial an mRNA-based vaccine candidate to reduce the rate of shingles. Moderna in Cambridge, Massachusetts, also has mRNA vaccine candidates for the viruses that cause genital herpes and shingles.

Monoclonal antibodies for malaria prevention.
Aleshnick Maya et al. Molecular therapy : the journal of the American Society of Gene Therapy 2022 4 (5) 1810-1821

Despite several approaches to prevent established infection, no single approach offers complete protection, so a multilayered approach is needed. One potential layer, the monoclonal antibody. opens in new tab, is the focus of a new trial. The authors describe protection conferred by a long-acting, next-generation monoclonal antibody against controlled human malaria infection in healthy persons.


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