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Main|Horizon Scan|PHGKB
Update Date: Jun 27, 2024

Effective August 1, 2024, this site was discontinued. All content will be preserved online for historical purposes only until 2029.

Genomics Precision Health Scan

Sickle cell disease and infertility risks: implications for counseling and care of affected girls and women.
Lydia H Pecker et al. Expert Rev Hematol 2024

A Pharmacist-Managed Hydroxyurea Prescribing Protocol Improves Uptake and Optimization among Patients with Sickle Cell Disease.
Cameron Roessner et al. Adv Hematol 2024 20244753349

Application of implementation science for improving the utilization of an international clinical practice guidance on familial hypercholesterolemia.
Laney K Jones et al. J Clin Lipidol 2024

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Advanced Molecular Detection Clips

Uganda launches Ebola Sudan vaccine trial; sequencing shows no link to 2022 outbreak
Schnirring L. CIDRAP, Feb 3, 2025.

GAO: Public-health workforce shortage undermines ability to respond to outbreaks, other emergencies
Van Beusekom M. CIDRAP, Jan 31, 2025.

Mpox outbreak in DR Congo, neighboring countries underscores threat of clade 1b
Soucheray S. CIDRAP, Jan 30, 2025.

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Non-Genomics Precision Health Scan

A machine learning-derived risk score to predict left ventricular diastolic dysfunction from clinical cardiovascular magnetic resonance imaging.
Qingtao Zhou et al. Front Cardiovasc Med 2024 111382418

Validation of artificial intelligence for epileptic seizure detection: Moving from research into the clinic.
Jonathan Dan et al. Dev Med Child Neurol 2024

Deep Learning Analysis for Predicting Tumor Spread through Air Space in Early-Stage Lung Adenocarcinoma Pathology Images.
De-Xiang Ou et al. Cancers (Basel) 2024 16(11)

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New CDC-Authored Publications

Antimalarial drug resistance and population structure of Plasmodium falciparum in Mozambique using genomic surveillance at health facilities in 2021 and 2022
Boene S , Rovira-Vallbona E , da Silva C , Garcia-Ulloa M , Rafael B , Canana N , Aranda-Diaz A , Cistero P , Garcia-Fernandez C , Tembisse D , Ndimande N , Chidimatembue A , Matambisso G , Palmer B , Chico AR , Dimene M , Saifodine A , Inacio J , da Silva M , Plucinski M , Bonnington C , Wate F , de Carvalho E , Mathe G , Pujol A , Arregui-Gallego B , Comiche K , Nhama A , Nhamussua L , Aide P , Saute F , Enosse S , Greenhouse B , Candrinho B , Mayor A .
Sci Rep 2025 15 (1) 29335 New Added Today type
Evaluation of long-term immunity following inoculation with highly diverse orthomarburgvirus isolates in Egyptian rousette bats (Rousettus aegyptiacus)
Elbert JA , Schuh AJ , Amman BR , Guito JC , Graziano JC , Sealy TK , Howerth EW , Towner JS .
J Virol 2025 e0084825 New Added Today type
Circular RNA hsa_circ_0099188 Regulates Inducible Nitric Oxide Synthase and Chemokine Transcription in Macrophages by Targeting the hsa-miR-381-3p/PPP3CA and hsa-miR-381-3p/KLF4 Pathways in Response to 4,4'-Methylene Diphenyl Diisocyanate-Glutathione Conjugate exposure
Lin CC , Law BF , Hettick JM .
Toxicol Sci 2025 New Added Today type

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Updates on Specific Topics

Additional Updates

Additional information includes our hot topics of the day, events, and  the latest CDC information on topics relevant to genomics and precision health. Also, check out the CDC Science Clips for weekly CDC-authored publications.

About

The PHGKB Weekly Horizon Scan features the latest information and publications on the public health impact of human genomics and family history, pathogen genomics and advanced molecular detection, machine learning and precision health technologies.  The update also features CDC publications in genomics and precision health. Articles listed in the update are selected by the Public Health Genomics Branch to provide current awareness of the public health literature. An article’s inclusion does not necessarily represent the views of the Centers for Disease Control and Prevention nor does it imply endorsement of the article’s methods or findings.

Disclaimer: Articles listed in the Public Health Genomics and Precision Health Knowledge Base are selected by the CDC Public Health Genomics Branch to provide current awareness of the literature and news. Inclusion in the update does not necessarily represent the views of the Centers for Disease Control and Prevention nor does it imply endorsement of the article's methods or findings. CDC and DHHS assume no responsibility for the factual accuracy of the items presented. The selection, omission, or content of items does not imply any endorsement or other position taken by CDC or DHHS. Opinion, findings and conclusions expressed by the original authors of items included in the update, or persons quoted therein, are strictly their own and are in no way meant to represent the opinion or views of CDC or DHHS. References to publications, news sources, and non-CDC Websites are provided solely for informational purposes and do not imply endorsement by CDC or DHHS.

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