Hot Topics of the Day are picked by experts to capture the latest information and publications on public health genomics and precision health for various diseases and health topics. Sources include published scientific literature, reviews, blogs and popular press articles.
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Archived Hot Topics of the Day By Date
Bridging digital health divides
A Agrawal, Science, August 28, 2020
The COVID-19 pandemic has accelerated digital health implementation in India and elsewhere, such as this telemedicine hub in New Delhi, expanding the reach of health care.
Emerging Pandemic Diseases: How We Got to COVID-19.
Morens David M et al. Cell 2020 Aug
Disease emergence reflects dynamic balances and imbalances, within complex globally distributed ecosystems comprising humans, animals, pathogens, and the environment. Understanding these variables is a necessary step in controlling future devastating disease emergences.
A New Mathematical Model for Controlled Pandemics Like COVID-19 : AI Implemented Predictions
LD Jones et al ARXIV, AUgust 24, 2020
Machine Reasoning to Assess Pandemics Risks: Case of USS Theodore Roosevelt
K Lai et al, ARXIV, August 24, 2020
Data Mining Approach to Analyze Covid19 Dataset of Brazilian Patients
JE Chire Saire, ARXIV, August 26, 2020
DeepSOCIAL: Social Distancing Monitoring and Infection Risk Assessment in COVID-19 Pandemic
M Rezaei et al, ARXIV, August 26, 2020
Global and Local Mutations in Bangladeshi SARS-CoV-2 Genomes
MM Hasan et al, BIORXIV, August 26, 2020
F Volpato et al, MEDRXIV, August 26, 2020
Artificial intelligence in radiation oncology
E Huynh et al, Nature Rev Clin Oncol, August 25, 2020
We provide an overview of the radiation therapy workflow with discussion of the implications that AI is likely to have on each step. We describe challenges associated with the clinical development and implementation of AI platforms in radiation oncology and provide our perspective on how these platforms might change the roles of radiotherapy medical professionals.
Efficacy of Selpercatinib in RET -Altered Thyroid Cancers.
Wirth Lori J et al. The New England journal of medicine 2020 Aug (9) 825-835
We enrolled patients with RET-mutant medullary thyroid cancer with or without previous vandetanib or cabozantinib treatment, as well as those with previously treated RET fusion-positive thyroid cancer, in a phase 1-2 trial of selpercatinib. Results show durable efficacy with mainly low-grade toxic effects in patients.
Selpercatinib Aimed at RET -Altered Cancers.
Kurzrock Razelle et al. The New England journal of medicine 2020 Aug (9) 868-869
A remarkable increase has occurred in the number of highly targeted drugs that have efficacy in patients with advanced cancers that harbor specific genomic alterations.