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Hot Topics of the Day|PHGKB
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03/31/2020

Hot Topics of the Day are picked by experts to capture the latest information and publications on public health genomics and precision health for various diseases and health topics. Sources include published scientific literature, reviews, blogs and popular press articles.

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Initial exploration of in utero microbial colonization
MC Collado et al, Nature, March 30, 2020

Analysis of the intestinal content of fetuses suggests very limited bacterial colonization with potential immunological roles, which opens new research questions.

Restrictions Are Slowing Coronavirus Infections, New Data Suggest- A database of daily fever readings shows that the numbers declined as people disappeared indoors.
DG McNeil, NY Times, March 30, 2020

A company that produces internet-connected thermometers, first created a national map of fever levels on March 22 and was able to spot the trend within a day. Since then, data from the health departments of New York State and Washington State have buttressed the finding, making it clear that social distancing is saving lives.

Early Spread of SARS-Cov-2 in the Icelandic Population
MEDRXIV, March 30, 2020

Using genome sequencing, this study found CoV-2 has spread widely in the Icelandic population outside of the high-risk groups targeted for testing by the healthcare system. Several strains of the virus cause these infections and the composition of known infections in Iceland changed rapidly. Children and females are less vulnerable than adults and males.

Africa Contributes SARS-CoV-2 Sequencing to COVID-19 Tracking
M Makoni, the Scientist, March 31, 2020

Coronavirus death rate is lower than previously reported, study says, but it's still deadlier than seasonal flu
A Azad, CNN, March 31, 2020

Estimates of the severity of coronavirus disease 2019: a model-based analysis
R Verity et al, Lancet Infectious Diseases, March 30, 2020

In the face of rapidly changing data, a range of case fatality ratio estimates for coronavirus disease 2019 (COVID-19) have been produced that differ substantially in magnitude. We aimed to provide robust estimates, accounting for censoring and ascertainment biases.

Covid-19 testing: overcoming challenges in the next phase of the epidemic
AK Manrai et al, Stat News, March 31, 2020

The Application of Internet-Based Sources for Public Health Surveillance (Infoveillance): Systematic Review.
Barros Joana M et al. Journal of medical Internet research 2020 Mar (3) e13680

Reviewing 162 publications, we determined infectious diseases to be the preferred case study (66.7%). Of the eight categories of Internet bases sources (search queries, social media, news, discussion forums, websites, web encyclopedia, and online obituaries), search queries and social media were applied in 95.1% (154/162) of the reviewed publications.


Disclaimer: Articles listed in Hot Topics of the Day are selected by Public Health Genomics Branch to provide current awareness of the scientific literature and news. Inclusion in the update does not necessarily represent the views of the Centers for Disease Control and Prevention nor does it imply endorsement of the article's methods or findings. CDC and DHHS assume no responsibility for the factual accuracy of the items presented. The selection, omission, or content of items does not imply any endorsement or other position taken by CDC or DHHS. Opinion, findings and conclusions expressed by the original authors of items included in the Clips, or persons quoted therein, are strictly their own and are in no way meant to represent the opinion or views of CDC or DHHS. References to publications, news sources, and non-CDC Websites are provided solely for informational purposes and do not imply endorsement by CDC or DHHS.
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