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Hot Topics of the Day|PHGKB
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03/03/2020

Hot Topics of the Day are picked by experts to capture the latest information and publications on public health genomics and precision health for various diseases and health topics. Sources include published scientific literature, reviews, blogs and popular press articles.

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Response to COVID-19 in Taiwan- Big Data Analytics, New Technology, and Proactive Testing
CJ Wang et al, JAMA, March 3, 2020

Taiwan learned from its 2003 SARS experience and established a public health response mechanism for enabling rapid actions for the next crisis. Well-trained and experienced teams of officials were quick to recognize the crisis and activated emergency management structures to address the emerging outbreak.

Cryptic transmission of novel coronavirus SARS-CoV-2 revealed by genomic epidemiology
T Bedford Blog, March 2, 2020

Genomic epidemiology focuses on using the genetic sequences of pathogens to understand patterns of transmission and spread. Viruses mutate quickly and accumulate changes during transmission from one infected individual to another. The novel coronavirus SARS-CoV-2 responsible for the emerging COVID-19 pandemic mutates at an average of two mutations per month.

Effect of Home Blood Pressure Monitoring via a Smartphone Hypertension Coaching Application or Tracking Application on Adults With Uncontrolled Hypertension- A Randomized Clinical Trial
SD Persell et al, JAMA Network Open, March 2, 2020

Does an artificial intelligence smartphone app improve blood pressure and hypertension-associated behaviors? In this randomized clinical trial of adults with uncontrolled hypertension, participants randomized to a smartphone coaching app did not have lower blood pressure at 6 months compared with those receiving a blood pressure tracking app.

Assessment of Expert-Level Automated Detection of Plasmodium falciparum in Digitized Thin Blood Smear Images
PC Kuo et al, JAMA Network Open, March 2, 2020

In this diagnostic study that used a 1-stage deep learning framework and benchmark data sets, the malaria detection algorithm achieved expert-level performance in detecting Plasmodium falciparum in thin blood smear images.

Genetic Screening of the Patients with Primary Immunodeficiency by Whole-
B Erman et al, Ped Allergy Immunol Pulm,February 2020

Primary immunodeficiencies are characterized by susceptibility to recurrent infections, allergy, malignancies and autoimmunity. The identification of disease-causing genetic defects is critically important for treatment options. In last decade, next-generation sequencing-based methods has enabled the rapid genetic screening.

Transforming Global Health with AI.
Mehta Mehul C et al. The New England journal of medicine 2020 Feb (9) 791-793

Artificial intelligence (AI) has the potential to revolutionize health and health care in LMICs by addressing the large knowledge and judgment gaps that make care delivery poor. AI utilizes machine-learning technology that analyzes and interprets large data sets, using powerful computing resources.


Disclaimer: Articles listed in Hot Topics of the Day are selected by Public Health Genomics Branch to provide current awareness of the scientific literature and news. Inclusion in the update does not necessarily represent the views of the Centers for Disease Control and Prevention nor does it imply endorsement of the article's methods or findings. CDC and DHHS assume no responsibility for the factual accuracy of the items presented. The selection, omission, or content of items does not imply any endorsement or other position taken by CDC or DHHS. Opinion, findings and conclusions expressed by the original authors of items included in the Clips, or persons quoted therein, are strictly their own and are in no way meant to represent the opinion or views of CDC or DHHS. References to publications, news sources, and non-CDC Websites are provided solely for informational purposes and do not imply endorsement by CDC or DHHS.
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