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Hot Topics of the Day|PHGKB
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01/24/2020

Hot Topics of the Day are picked by experts to capture the latest information and publications on public health genomics and precision health for various diseases and health topics. Sources include published scientific literature, reviews, blogs and popular press articles.

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Archived Hot Topics of the Day By Date

The microbes in your gut could predict whether you’re likely to die in the next 15 years
RP Ortega, Science, January 22, 2020

The predictive power of the microbiome exceeds that of genome-wide association studies in the discrimination of complex human disease
BT Tierney et al, BIORXIV, January 2020

Our results demonstrate the relative predictive ability of the microbiome, indicating that it may outperform human genetics in discriminating human disease cases and controls. They additionally motivate the need for population-level microbiome sequencing resources, akin to the UK Biobank, to further improve and reproduce metagenomic models of disease.

Deep phenotyping during pregnancy for predictive and preventive medicine
AG Paquette et al, Scit Trans Medicine, Januar 22, 2020

Systems biology offers a holistic approach to deciphering physiology or disease by deriving and integrating biological information to delineate relevant networks and their dynamics. We discuss why pregnancy is particularly well suited for prototyping deep phenotyping, scientific wellness, and related systems biology approaches to predictive medicine.

Your Fitbit could help health officials predict flu outbreaks in real-time
A Kim, CNN, January 2020

Researchers reviewed de-identified data from users wearing Fitbits -- the company's privacy policy allows for the potential use of de-identified user data for research, and found that they were able to do real-time flu prediction at the state level. This is the first time heart rate trackers and sleep data have been used to predict infectious disease in real time.

SMART Markers: collecting patient-generated health data as a standardized property of health information technology
R Sayeed, et al, NPJ Digital Medicine, January 23, 2020

We sought to make collecting patient-generated health data (PGHD) a fundamental property of health information technology at scale, and in an interoperable, standards-compliant fashion. We build upon the open SMART on FHIR (Fast Health Interoperability Resources) specification to create SMART Markers—a mobile device software framework.


Disclaimer: Articles listed in Hot Topics of the Day are selected by Public Health Genomics Branch to provide current awareness of the scientific literature and news. Inclusion in the update does not necessarily represent the views of the Centers for Disease Control and Prevention nor does it imply endorsement of the article's methods or findings. CDC and DHHS assume no responsibility for the factual accuracy of the items presented. The selection, omission, or content of items does not imply any endorsement or other position taken by CDC or DHHS. Opinion, findings and conclusions expressed by the original authors of items included in the Clips, or persons quoted therein, are strictly their own and are in no way meant to represent the opinion or views of CDC or DHHS. References to publications, news sources, and non-CDC Websites are provided solely for informational purposes and do not imply endorsement by CDC or DHHS.
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