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Health Equity PHGKB

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Last Posted: May 10, 2021
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United States COVID-19 Pandemic Vulnerability Index by County
CDC COVID Data Tracker, May 2021

This dashboard is based on the National Institute of Environmental Health Sciences’ (NIEHS) COVID-19 Pandemic Vulnerability Index (PVI), an interactive mapping application visualizing risk profiles of vulnerability to COVID-19 epidemics for the 3,142 counties in the U.S. Details on variable inclusion and methodology on PVI.

Ensuring that biomedical AI benefits diverse populations
J Zhou et al, E Biomedicine, May 4, 2021

Artificial Intelligence (AI) can potentially impact many aspects of human health, from basic research discovery to individual health assessment. It is critical that these advances in technology broadly benefit diverse populations from around the world. This can be challenging because AI algorithms are often developed on non-representative samples and evaluated based on narrow metrics. Here we outline key challenges to biomedical AI in outcome design, data collection and technology evaluation, and use examples from precision health to illustrate how bias and health disparity may arise.

Toward a fine-scale population health monitoring system
G Belbin et al, Cell, April 15, 2021

We propose a framework for repurposing data from electronic health records (EHRs) in concert with genomic data to explore the demographic ties that can impact disease burdens. Using data from a diverse biobank in New York City, we identified 17 communities sharing recent genetic ancestry. We observed 1,177 health outcomes that were statistically associated with a specific group and demonstrated significant differences in segregation of variants contributing to Mendelian diseases.

Personal Reflections on Genomics, Health Equity, and Public Health
M Rose et al, CDC Blog Post, April 19, 2021

Genomics provides opportunities to prevent, treat, or manage diseases by identifying genetic changes before signs or symptoms of disease occur. But not everyone receives the benefits provided by genomics, and some have even claimed that genomics might widen health disparities among some racial and ethnic minority groups.


news Latest News and Publications
Association of Multigenerational Family History of Depression With Lifetime Depressive and Other Psychiatric Disorders in Children: Results from the Adolescent Brain Cognitive Development (ABCD) Study. External Web Site Icon
van Dijk Milenna T et al. JAMA psychiatry 2021
Genetic Determinants of Poor Response to Treatment in Severe Asthma. External Web Site Icon
Figueiredo Ricardo G et al. International journal of molecular sciences 2021 22(8)
Tracking the emergence of disparities in the subnational spread of COVID-19 in Brazil using an online application for real-time data visualisation External Web Site Icon
P Mee et al, MEDRXIV May 4, 2021
Ensuring that biomedical AI benefits diverse populations External Web Site Icon
J Zhou et al, E Biomedicine, May 4, 2021
Building a social media-based HIV risk behavior index to inform the prediction of HIV new diagnosis: a feasibility study. External Web Site Icon
Li Zhenlong et al. AIDS (London, England) 2021 35(Suppl 1) S91-S99
Development and Validation of a Machine Learning Model to Estimate Bacterial Sepsis Among Immunocompromised Recipients of Stem Cell Transplant. External Web Site Icon
Lind Margaret L et al. JAMA network open 2021 4(4) e214514
Artificial neural network to predict the effect of obesity on the risk of tuberculosis infection. External Web Site Icon
Badawi Alaa et al. Journal of public health research 2021 10(1)
African American Nurses' Perspectives on Genomic Medicine Research. External Web Site Icon
Hendricks-Sturrup Rachele M et al. AMA journal of ethics 2021 23(3) E240-251
Carrier frequency and incidence estimation of Smith-Lemli-Opitz syndrome in East Asian populations by Genome Aggregation Database (gnomAD) based analysis. External Web Site Icon
Park Jong Eun et al. Orphanet journal of rare diseases 2021 16(1) 166
Pitfalls and challenges in genetic test interpretation: An exploration of genetic professionals experience with interpretation of results. External Web Site Icon
Donohue Katherine E et al. Clinical genetics 2021 99(5) 638-649
Global approaches to cardiogenetic evaluation after sudden cardiac death in the young: A survey among healthcare professionals. External Web Site Icon
van den Heuvel Lieke M et al. Heart rhythm 2021
Telomere length and socioeconomic status at neighborhood and individual levels among 80,000 adults in the Genetic Epidemiology Research on Adult Health and Aging cohort. External Web Site Icon
Alexeeff Stacey E et al. Environmental epidemiology (Philadelphia, Pa.) 2019 3(3) e049
COVID-19 pandemic and health-care disruptions: count the most vulnerable External Web Site Icon
J Kumar, Lancet Global Health, March 31, 2021
Digital Mental Health Challenges and the Horizon Ahead for Solutions. External Web Site Icon
Balcombe Luke et al. JMIR mental health 2021 8(3) e26811
Knowledge and psychosocial impact of genetic counseling and multigene panel testing among individuals with ovarian cancer. External Web Site Icon
Pozzar Rachel A et al. Familial cancer 2021
Predicting Hospitalization Due to COPD Exacerbations in Swedish Primary Care Patients Using Machine Learning - Based on the ARCTIC Study. External Web Site Icon
Ställberg Björn et al. International journal of chronic obstructive pulmonary disease 2021 16677-688
Counties with lower insurance coverage are associated with both slower vaccine rollout and higher COVID-19 incidence across the United States External Web Site Icon
E Lindemer et al, MEDRXIV, March 26, 2021
Exploring racial and ethnic minority individuals' journey to becoming genetic counselors: Mapping paths to diversifying the genetic counseling profession. External Web Site Icon
Alvarado-Wing Tatiana E et al. Journal of genetic counseling 2021
Integrating Genomic Screening into Primary Care: Provider Experiences Caring for Latino Patients at a Community-Based Health Center. External Web Site Icon
Srinivasan Tarika et al. Journal of primary care & community health 2021 1221501327211000242
Preparing genetic counselors to serve Native American communities. External Web Site Icon
Freeman Abigail A et al. Journal of genetic counseling 2021
Dermatologic Research Potential of the Observational Health Data Sciences and Informatics (OHDSI) Network. External Web Site Icon
Sivesind Torunn Elise et al. Dermatology (Basel, Switzerland) 2021 1-9
Modelling the impact of rapid tests, tracing and distancing in lower-income countries suggest optimal policies varies with rural-urban settings External Web Site Icon
X Jiang et al, MEDRXIV, March 20, 2021
Resources for Disproportionately Affected Communities
CDC, March 2021
Show us the Data: Global COVID-19 Wastewater Monitoring Efforts, Equity, and Gaps External Web Site Icon
CC Naughton et al, MEDRXIV, March 17, 2021
Machine Learning Assessment of Early Life Factors Predicting Suicide Attempt in Adolescence or Young Adulthood. External Web Site Icon
Navarro Marie C et al. JAMA network open 2021 4(3) e211450
COVID-19 Risk Factors and Mortality among Native Americans External Web Site Icon
ML Barr et al, MEDRXIV, March 13, 2021
High household transmission of SARS-CoV-2 in the United States: living density, viral load, and disproportionate impact on communities of color External Web Site Icon
C Cerami et al MEDRXIV, March 12, 2021
Risk for COVID-19 Infection, Hospitalization, and Death By Race/Ethnicity
CDC, March 12, 2021
Prenatal exposure to air pollutants and childhood atopic dermatitis and allergic rhinitis adopting machine learning approaches: 14-year follow-up birth cohort study. External Web Site Icon
Huang Yu et al. The Science of the total environment 2021 777145982
Measuring the exposure of Black, Asian and other ethnic groups to Covid-infected neighbourhoods in English towns and cities External Web Site Icon
R Harris et al, MEDRXIV, March 8,2021

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Disclaimer: Articles listed in the Public Health Knowledge Base are selected by the CDC Office of Public Health Genomics to provide current awareness of the literature and news. Inclusion in the update does not necessarily represent the views of the Centers for Disease Control and Prevention nor does it imply endorsement of the article's methods or findings. CDC and DHHS assume no responsibility for the factual accuracy of the items presented. The selection, omission, or content of items does not imply any endorsement or other position taken by CDC or DHHS. Opinion, findings and conclusions expressed by the original authors of items included in the update, or persons quoted therein, are strictly their own and are in no way meant to represent the opinion or views of CDC or DHHS. References to publications, news sources, and non-CDC Websites are provided solely for informational purposes and do not imply endorsement by CDC or DHHS.

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