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Health Equity PHGKB

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Last Posted: Oct 01, 2022
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Knowledge and Attitudes about Privacy and Secondary Data Use among African-Americans Using Direct-to-Consumer Genetic Testing.
Ziegler Emily et al. Public health genomics 2022 9 1-10

This study found that African-American consumers of DTC GT had a positive outlook about genetic testing and were open to research and some nonresearch uses, provided that they were able to give informed consent. Participants in this study had little knowledge of company practices regarding secondary uses. Compared to an earlier cohort of European American participants, African-American participants expressed more concerns about medical and law enforcement communities’ use of data and more reference to community engagement.

Sickle Cell Disease and Gene Therapy - Patient and Physician Perspectives.
DeBaun Michael et al. The New England journal of medicine 2022 9 (13) e28

In this short documentary video, patients and physicians partner both to highlight the experience of living with sickle cell disease and to discuss the pathophysiology of the disease and new treatment strategies, including gene therapy. Patients share their own stories of interactions with the health care system and explore the challenging topics of racial disparity and health equity. Physicians express a cautious optimism as they review the risks and benefits of gene therapy.

The AI life cycle: a holistic approach to creating ethical AI for health decisions
MY Ng et al, Nature Medicine, September 26, 2022

Artificial intelligence (AI) has the potential to revolutionize many aspects of clinical care, but it can also lead to patient and community harm, the misallocation of health resources and the exacerbation of existing health inequities, which greatly threaten its overall efficacy and social impact1. These issues have prompted the movement toward ethical AI, a field devoted to raising and addressing ethical issues related to the development and application of AI.

Tackling bias in AI health datasets through the STANDING Together initiative
S Ganapathi et al, Nature Medicine, September 26, 2022

Despite the enormous potential of Artificial Intelligence (AI) as a Medical Device (AIaMDs), their rapid growth in healthcare has been accompanied by concerns that AI models may learn biases engrained in medical practice and exacerbate health inequalities. This has been exemplified by several AI systems that have shown the ability of algorithms to systematically misrepresent and exacerbate health problems in minority groups.


news Latest News and Publications
SARS-CoV-2 mRNA vaccination elicits broad and potent Fc effector functions to VOCs in vulnerable populations. External Web Site Icon
Hederman Andrew P, et al. medRxiv : the preprint server for health sciences 2022 0 0.
Early identification of a COVID-19 outbreak detected by wastewater surveillance at a large homeless shelter in Toronto, Ontario. External Web Site Icon
Akingbola Samantha, et al. Canadian journal of public health = Revue canadienne de sante publique 2022 0 0.
Effectiveness and safety of lanadelumab in ethnic and racial minority subgroups of patients with hereditary angioedema: results from phase 3 studies. External Web Site Icon
Craig Timothy J, et al. Allergy, asthma, and clinical immunology : official journal of the Canadian Society of Allergy and Clinical Immunology 2022 0 0. (1) 85
Incidence of Severe COVID-19 Illness Following Vaccination and Booster With BNT162b2, mRNA-1273, and Ad26.COV2.S Vaccines. External Web Site Icon
Kelly J Daniel, et al. JAMA 2022 0 0.
Household transmission of the SARS-CoV-2 Omicron variant in Denmark. External Web Site Icon
Lyngse Frederik Plesner, et al. Nature communications 2022 0 0. (1) 5573
Causal connections between socioeconomic disparities and COVID-19 in the USA. External Web Site Icon
Banerjee Tannista, et al. Scientific reports 2022 0 0. (1) 15827
COVID-19 Severity and Mortality after Vaccination against SARS-CoV-2 in Central Greece. External Web Site Icon
Samara Athina A, et al. Journal of personalized medicine 2022 0 0. (9)
Identifying the High-Risk Population for COVID-19 Transmission in Hong Kong Leveraging Explainable Machine Learning. External Web Site Icon
Jiang Zhihan, et al. Healthcare (Basel, Switzerland) 2022 0 0. (9)
Longitudinal Comparison of Neutralizing Antibody Responses to COVID-19 mRNA Vaccines after Second and Third Doses. External Web Site Icon
Roeder Alexa J, et al. Vaccines 2022 0 0. (9)
Third Early "Booster" Dose Strategy in France of bnt162b2 SARS-CoV-2 Vaccine in Allogeneic Hematopoietic Stem Cell Transplant Recipients Enhances Neutralizing Antibody Responses. External Web Site Icon
Ahmed-Belkacem Abdelhakim, et al. Viruses 2022 0 0. (9)
Using a Cloud-Based Machine Learning Classification Tree Analysis to Understand the Demographic Characteristics Associated With COVID-19 Booster Vaccination Among Adults in the United States. External Web Site Icon
Meng Lu, et al. Open forum infectious diseases 2022 0 0. (9) ofac446
Angiotensin-converting enzyme 1 and voltage-gated potassium channel-interacting protein 4 gene polymorphisms in COVID-19 patients from East of Iran. External Web Site Icon
Abbaszadeh Hamid, et al. Clinica chimica acta; international journal of clinical chemistry 2022 0 0.
Germany's fourth COVID-19 wave was mainly driven by the unvaccinated. External Web Site Icon
Maier Benjamin F, et al. Communications medicine 2022 0 0. 116
Frequency of Bacteremia and Urinary Tract Infection in Pediatric Renal Transplant Recipients. External Web Site Icon
Cruz Andrea T, et al. The Pediatric infectious disease journal 2022 0 0.
Mortality Risk Among Patients Hospitalized Primarily for COVID-19 During the Omicron and Delta Variant Pandemic Periods - United States, April 2020-June 2022. External Web Site Icon
Adjei Stacey et al. MMWR. Morbidity and mortality weekly report 2022 9 (37) 1182-1189
Racial disparities in COVID-19 outcomes: Unwarranted statistical adjustments and the perpetuation of stereotypes External Web Site Icon
SP Massion et al, Lancet Regional Health, September 2022
Lineage BA.2 dominated the Omicron SARS-CoV-2 epidemic wave in the Philippines. External Web Site Icon
Li Yao-Tsun, et al. Virus evolution 2022 0 0. (2) veac078
COVID-19 infection and transmission includes complex sequence diversity. External Web Site Icon
Chan Ernest R, et al. PLoS genetics 2022 0 0. (9) e1010200
Modelling the impact of rapid tests, tracing and distancing in lower-income countries suggest that optimal policies vary with rural-urban settings External Web Site Icon
R Jiang et al, MEDRXIV, September 8, 2022
Clinical characteristics analysis of COVID-19 patients from the first significant community outbreak by SARS-CoV-2 variant B.1.1.7 in Taiwan as experienced from a single northern medical center. External Web Site Icon
Huang Ruei-Chang, et al. Journal of microbiology, immunology, and infection = Wei mian yu gan ran za zhi 2022 0 0.
Handling class imbalance in COVID-19 chest X-ray images classification: Using SMOTE and weighted loss. External Web Site Icon
Chamseddine Ekram, et al. Applied soft computing 2022 0 0. 109588
A machine learning analysis of COVID-19 mental health data. External Web Site Icon
Rezapour Mostafa, et al. Scientific reports 2022 0 0. (1) 14965
Post-COVID Conditions: CDC Science How CDC is using science to learn more about post-COVID conditions (or long COVID)
CDC, September 2, 2022
Socio-economic analysis of short-term trends of COVID-19: modeling and data analytics. External Web Site Icon
El Jai Mostapha, et al. BMC public health 2022 0 0. (1) 1633
The Impact of the COVID-19 Pandemic on Internet Use and Use of Digital Health Tools: A Secondary Analysis of the 2020 Health Information National Trends Survey. External Web Site Icon
Zeng Billy, et al. Journal of medical Internet research 2022 0 0.
A pre-trained convolutional neural network with optimized capsule networks for chest X-rays COVID-19 diagnosis. External Web Site Icon
AbouEl-Magd Lobna M, et al. Cluster computing 2022 0 0. 1-15
BNT162b2 induced neutralizing and non-neutralizing antibody functions against SARSCoV-2 diminish with age. External Web Site Icon
Bates Timothy A, et al. medRxiv : the preprint server for health sciences 2022 0 0.
Perspectives from leadership and frontline staff on telehealth transitions in the Los Angeles safety net during the COVID-19 pandemic and beyond. External Web Site Icon
Casillas Alejandra, et al. Frontiers in digital health 2022 0 0. 944860
Rapid Implementation of a Community-Academic Partnership Model to Promote COVID-19 Vaccine Equity within Racially and Ethnically Minoritized Communities. External Web Site Icon
Abdul-Mutakabbir Jacinda C, et al. Vaccines 2022 0 0. (8)
Exploring socioeconomic status as a global determinant of COVID-19 prevalence, using exploratory data analytic and supervised machine learning techniques. External Web Site Icon
Winston Luke, et al. JMIR formative research 2022 0 0.
Targeted therapy in Coronavirus disease 2019 (COVID-19): Implication from cell and gene therapy to immunotherapy and vaccine. External Web Site Icon
Shirzad Moein, et al. International immunopharmacology 2022 0 0. 109161
Phytochemical drug discovery for COVID-19 using high-resolution computational docking and machine learning assisted binder prediction. External Web Site Icon
Wang Zirui, et al. Journal of biomolecular structure & dynamics 2022 0 0. 1-21
Comparison of SARS-CoV-2 spike RNA sequences in feces and nasopharynx indicates intestinal replication. External Web Site Icon
Beck-Friis Thomas, et al. Gut pathogens 2022 0 0. (1) 35
Predicting COVID-19 Infections in Eswatini Using the Maximum Likelihood Estimation Method. External Web Site Icon
Dlamini Sabelo Nick, et al. International journal of environmental research and public health 2022 0 0. (15)
Clinical and Genetic Risk Factors for Acute Incident Venous Thromboembolism in Ambulatory Patients With COVID-19. External Web Site Icon
Xie JunQing, et al. JAMA internal medicine 2022 0 0.
Loss of Pfizer (BNT162b2) Vaccine-Induced Antibody Responses against the SARS-CoV-2 Omicron Variant in Adolescents and Adults. External Web Site Icon
Gupta Sneh Lata, et al. Journal of virology 2022 0 0. e0058222
Telehealth Perceptions Among US Immigrant Patients at an Academic Internal Medicine Practice: Cross-sectional Study. External Web Site Icon
Levine Susan, et al. JMIR human factors 2022 0 0. (3) e36069
Considering Race and Ethnicity in Covid Risk Assessments - Legal Concerns and Possible Solutions. External Web Site Icon
Jost Timothy S et al. The New England journal of medicine 2022 8 (6) 481-483
Towards Control and Oversight of SARS-CoV-2 Diagnosis and Monitoring through Multiplexed Quantitative Electroanalytical Immune Response Biosensors. External Web Site Icon
Torrente-Rodríguez Rebeca M, et al. Angewandte Chemie (Weinheim an der Bergstrasse, Germany) 2022 0 0. (28) e202203662
A spatiotemporal decay model of human mobility when facing large-scale crises. External Web Site Icon
Li Weiyu, et al. Proceedings of the National Academy of Sciences of the United States of America 2022 0 0. (33) e2203042119

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Disclaimer: Articles listed in the Public Health Knowledge Base are selected by the CDC Office of Public Health Genomics to provide current awareness of the literature and news. Inclusion in the update does not necessarily represent the views of the Centers for Disease Control and Prevention nor does it imply endorsement of the article's methods or findings. CDC and DHHS assume no responsibility for the factual accuracy of the items presented. The selection, omission, or content of items does not imply any endorsement or other position taken by CDC or DHHS. Opinion, findings and conclusions expressed by the original authors of items included in the update, or persons quoted therein, are strictly their own and are in no way meant to represent the opinion or views of CDC or DHHS. References to publications, news sources, and non-CDC Websites are provided solely for informational purposes and do not imply endorsement by CDC or DHHS.

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