Leber Hereditary Optic Neuropathy
What's New
Last Posted: Jan 05, 2023
- Is the disease risk and penetrance in Leber hereditary optic neuropathy actually low?
Mackey David A et al. American journal of human genetics 2022 - Low disease risk and penetrance in Leber hereditary optic neuropathy.
Watson Eloise C et al. American journal of human genetics 2022 - Safety of Intravitreal Gene Therapy for Treatment of Subjects with Leber Hereditary Optic Neuropathy due to Mutations in the Mitochondrial ND4 Gene: The REVEAL Study.
Vignal-Clermont Catherine et al. BioDrugs : clinical immunotherapeutics, biopharmaceuticals and gene therapy 2021 Feb - A hospital-based five-year prospective study on the prevalence of Leber's hereditary optic neuropathy with genetic confirmation.
Gowri Poigaialwar et al. Molecular vision 2020 26789-796 - Bilateral visual improvement with unilateral gene therapy injection for Leber hereditary optic neuropathy
P Yu et al, Sci Trans Med, December 9, 2020 - Real-World Clinical Experience With Idebenone in the Treatment of Leber Hereditary Optic Neuropathy.
Catarino Claudia B et al. Journal of neuro-ophthalmology : the official journal of the North American Neuro-Ophthalmology Society 2020 Sep - Long-term screening for primary mitochondrial DNA variants associated with Leber Hereditary Optic Neuropathy: incidence, penetrance and clinical features.
Marotta Rosetta et al. Mitochondrion 2020 Aug - Mitochondrial disorders and drugs: what every physician should know.
Orsucci Daniele et al. Drugs in context 2019 8212588 - Optimization of a genotyping screening based on hydrolysis probes to detect the main mutations related to Leber hereditary optic neuropathy (LHON).
Martins Fábio Tadeu Arrojo et al. Molecular vision 2017 23495-503 - International Consensus Statement on the Clinical and Therapeutic Management of Leber's Hereditary Optic Neuropathy.
Carelli Valerio et al. Journal of neuro-ophthalmology : the official journal of the North American Neuro-Ophthalmology Society 2017 Oct
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- Page last reviewed:Feb 1, 2024
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