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Hot Topics of the Day|PHGKB
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11/29/2019

Hot Topics of the Day are picked by experts to capture the latest information and publications on public health genomics and precision health for various diseases and health topics. Sources include published scientific literature, reviews, blogs and popular press articles.

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Optimizing genetics online resources for diverse readers.
Chang Jiyoo et al. Genetics in medicine : official journal of the American College of Medical Genetics 2019 Nov

Commonly used educational materials were more complex than the recommended reading level for the general public. Genetic health information entries from Genetics Home Reference (n?=?1279) were written at a median 13.0 grade level. MedlinePlus entries, which are not exclusively genetic (n?=?1030), had a median grade level of 7.7.

Genomic screening and genomic diagnostic testing—two very different kettles of fish
L Biesecker, Genome Medicine, November 27, 2019

Genomic testing can be misunderstood as being determinative, when in reality it is the same as all other tests and context is essential for its correct interpretation. Two hypothetical cases of testing demonstrate how clinicians should contextualize genomic test results and the implementation of Bayes theorem in clinical decision-making.

Malaria parasites fine-tune mutations to resist drugs
L Tilley et al,Nature, November 27, 2019

Modified mosquitoes reduce cases of dengue fever- Insects infected with a disease-inhibiting bacterium were released in communities in Asia and South America
E Callaway, Nature, November 27, 2019

The findings, presented on 21 November at the annual meeting of the American Society of Tropical Medicine and Hygiene in National Harbor, Maryland, come from experimental releases of mosquitoes that carry Wolbachia bacteria, which block the replication of mosquito-borne pathogens such as the dengue, chikungunya and Zika viruses.

Epidemiologic Research in Dry Eye Disease and the Utility of Mobile Health Technology
MTM Wang et al, JAMA Ophthalmology, November 28 2019

One of the particularly novel aspects of the current study was the use of a crowdsourced smartphone application for the purpose of epidemiologic data collection. The use of mobile health technology tools offers the ability to collect detailed information from a large population in a relatively cost-effective, time-efficient, and user-friendly manner.


Disclaimer: Articles listed in Hot Topics of the Day are selected by Public Health Genomics Branch to provide current awareness of the scientific literature and news. Inclusion in the update does not necessarily represent the views of the Centers for Disease Control and Prevention nor does it imply endorsement of the article's methods or findings. CDC and DHHS assume no responsibility for the factual accuracy of the items presented. The selection, omission, or content of items does not imply any endorsement or other position taken by CDC or DHHS. Opinion, findings and conclusions expressed by the original authors of items included in the Clips, or persons quoted therein, are strictly their own and are in no way meant to represent the opinion or views of CDC or DHHS. References to publications, news sources, and non-CDC Websites are provided solely for informational purposes and do not imply endorsement by CDC or DHHS.
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