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Hot Topics of the Day|PHGKB
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10/27/2019

Hot Topics of the Day are picked by experts to capture the latest information and publications on public health genomics and precision health for various diseases and health topics. Sources include published scientific literature, reviews, blogs and popular press articles.

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Archived Hot Topics of the Day By Date

Comparative Tumor RNA Sequencing Analysis for Difficult-to-Treat Pediatric and Young Adult Patients With Cancer
OM Vaske et al, JAMA Network Open, October 25, 2019

This study suggests that tumor RNA-Seq comparisons may be feasible and highlight the potential clinical utility of incorporating such comparisons into clinical genomic interpretation for difficult-to-treat pediatric and young adult patients with cancer.

Vision of the Future of Medical Science
Francis Collins, Time, October 25, 2019

Among the many efforts now poised to change the future of health are those to harness the power of gene editing, expand the reach of cancer immunotherapy, map the human brain and build a solid foundation for a more individualized approach to health care, often called precision medicine.

Intensive DNA search yields 10 genes tied directly to schizophrenia
J Kaiser, Science, October 25, 2019

By scouring the DNA of tens of thousands of people, gene hunters have for the first time nabbed a handful of rare genes that, when mutated, appear to be direct contributors to the disease—and may shed light on what goes awry in a schizophrenia patient’s brain.

Harnessing the Power of Microbes to Fight Cancer
JP Zegerac, Medscape, October 25, 2019

A study in patients with melanoma indicate that users of probiotics have one-third the odds of responding to immunotherapy treatment with anti-programmed cell death-1 checkpoint inhibitors compared with patients not taking probiotics. The study found that patients on probiotics have decreased diversity of the microbiome.", a key measure of overall gut health.


Disclaimer: Articles listed in Hot Topics of the Day are selected by Public Health Genomics Branch to provide current awareness of the scientific literature and news. Inclusion in the update does not necessarily represent the views of the Centers for Disease Control and Prevention nor does it imply endorsement of the article's methods or findings. CDC and DHHS assume no responsibility for the factual accuracy of the items presented. The selection, omission, or content of items does not imply any endorsement or other position taken by CDC or DHHS. Opinion, findings and conclusions expressed by the original authors of items included in the Clips, or persons quoted therein, are strictly their own and are in no way meant to represent the opinion or views of CDC or DHHS. References to publications, news sources, and non-CDC Websites are provided solely for informational purposes and do not imply endorsement by CDC or DHHS.
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