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Hot Topics of the Day|PHGKB
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07/20/2020

Hot Topics of the Day are picked by experts to capture the latest information and publications on public health genomics and precision health for various diseases and health topics. Sources include published scientific literature, reviews, blogs and popular press articles.

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A unified catalog of 204,938 reference genomes from the human gut microbiome
A Almeida et al, NATure Biotech, July 20, 2020

We present the Unified Human Gastrointestinal Genome (UHGG) collection, comprising 204,938 nonredundant genomes from 4,644 gut prokaryotes. These genomes encode >170 million protein sequences

Characterization of Microbial Co-infections in the Respiratory Tract of hospitalized COVID-19 patients
H Zong et al, MEDRXIV, July 20, 2020

Genomic epidemiology of SARS-CoV-2 reveals multiple lineages and early spread of SARS-CoV-2 infections in Lombardy, Italy
C Alteri et al, MEDRXIV, July 20, 2020

From February to April, 2020, Lombardy (Italy) was the area who worldwide registered the highest numbers of SARS-CoV-2 infection. By extensively analyzing 346 whole SARS-CoV-2 genomes, we demonstrated the simultaneous circulation in Lombardy of two major viral lineages, likely derived from multiple introductions, occurring since the second half of January.

Development and Validation of a Web-Based Severe COVID-19 Risk Prediction Model
SH Woo et al, MEDRXIV, July 18, 2020

The utility of established prognostic scores in COVID-19 hospital admissions: a multicentre prospective evaluation of CURB-65, NEWS2, and qSOFA
F Frost et al, MEDRXIV, July 18, 2020

The landscape of SARS-CoV-2 RNA modifications
M Miladi et al, BIORXIV, July 18, 2020

Predicting Mechanical Ventilation Requirement and Mortality in COVID-19 using Radiomics and Deep Learning on Chest Radiographs: A Multi-Institutional Study
J Bae et al, ARXIV, July 15, 2020

Modeling the progression of SARS-CoV-2 infection in patients with COVID-19 risk factors through predictive analysis
J Leon-Abarca, MEDRXIV, July 19, 2020

SARS-CoV-2 viral load in the upper respiratory tract of children and adults with early acute COVID-19
S Baggio et al, MEDRXIV, July 19, 2020


Disclaimer: Articles listed in Hot Topics of the Day are selected by Public Health Genomics Branch to provide current awareness of the scientific literature and news. Inclusion in the update does not necessarily represent the views of the Centers for Disease Control and Prevention nor does it imply endorsement of the article's methods or findings. CDC and DHHS assume no responsibility for the factual accuracy of the items presented. The selection, omission, or content of items does not imply any endorsement or other position taken by CDC or DHHS. Opinion, findings and conclusions expressed by the original authors of items included in the Clips, or persons quoted therein, are strictly their own and are in no way meant to represent the opinion or views of CDC or DHHS. References to publications, news sources, and non-CDC Websites are provided solely for informational purposes and do not imply endorsement by CDC or DHHS.
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