Skip directly to search Skip directly to A to Z list Skip directly to navigation Skip directly to page options Skip directly to site content


Hot Topics of the Day|PHGKB
Search PHGKB:

06/30/2020

Hot Topics of the Day are picked by experts to capture the latest information and publications on public health genomics and precision health for various diseases and health topics. Sources include published scientific literature, reviews, blogs and popular press articles.

Sign up MyPHGKB to receive the daily hot topic email alert.

Search Archive:
Archived Hot Topics of the Day By Date

Deciphering the Role of Host Genetics in Susceptibility to Severe COVID-19
ME Carter-Timoufle et al, Frontiers in Immunology, June 30, 2020

While COVID-19 disease is most serious in patients with co-morbidities, the reason for healthy individuals succumbing to fulminant infection is largely unexplained. We discuss the most recent findings in terms of clinical features and the host immune response, and suggest candidate athways that may be compromised in healthy individuals with fulminating COVID-19.

Multiple approaches for massively parallel sequencing of SARS-CoV-2 genomes directly from clinical samples
M Xiao et al Genome Medicine, June 30, 2020

End-to-End AI-Based Point-of-Care Diagnosis System for Classifying Respiratory Illnesses and Early Detection of COVID-19
AN Belkacem et al, ARXIV, June 28, 2020

Is a “Cytokine Storm” Relevant to COVID-19?
P Sinha et al, JAMA Internal Medicine, June 30, 2020

the term cytokine storm may be misleading in COVID-19 ARDS. Incorporating a poorly defined pathophysiological entity lacking a firm biological diagnosis may only further increase uncertainty about how best to manage this heterogeneous population of patients.

Applications of digital technology in COVID-19 pandemic planning and response
S Whitelaw et al, Lancet Digital Health, June 29, 2020

This Viewpoint provides a framework for the application of digital technologies in pandemic management and response, highlighting ways in which successful countries have adopted these technologies for pandemic planning, surveillance, testing, contact tracing, quarantine, and health care.

AIDCOV: An Interpretable Artificial Intelligence Model for Detection of COVID-19 from Chest Radiography Images
MZ et al, MEDRXIV, June 29, 2020

Assessment of the use and quick preparation of saliva for rapid microbiological diagnosis of COVID-19.
J Vila et al, BIORXIV, June 29, 2020

Privacy challenges and research opportunities for genomic data sharing
L Bonomi et al, Nature Genetics, June 29, 2020

In this work, we provide an overview of major privacy threats identified by the research community and examine the privacy challenges in the context of emerging direct-to-consumer genetic-testing applications. We additionally present general privacy-protection techniques for genomic data sharing and their potential applications.

Telehealth: What You Need to Know About a Virtual Doctor Visit
NIH, June 2020

Telehealth is a collection of means or methods for enhancing health care, public health and health education delivery and support using telecommunications technologies. The most conventional type is live video conferencing where both the doctor and patient use a computer or mobile device with video and audio to have a conversation and medical exam.

AI dual-stain approach improved accuracy, efficiency of cervical cancer screening in NCI study
NCI, June 2020 Brand

In recent years, clinicians have hoped to take advantage of advances in digital imaging and machine learning to improve cervical cancer screening. The challenge is to identify which women with positive HPV test results are most likely to have precancerous changes in their cervical cells.

Gene and Stem Cell Therapies for Fetal Care- A Review
AE O'Connell, JAMA Pediatrics, June 29, 2020

Fetal stem cell and gene therapy bring important therapeutic opportunities for select disorders that present in the fetal and neonatal periods. While this field is in its infancy, these therapies are starting to be available clinically, and clinicians should be aware of their benefits and challenges.

Cystic Fibrosis
CDC, June 2020 Brand

Cystic fibrosis (CF) is a genetic disorder that causes problems with breathing and digestion. People with cystic fibrosis (CF) are among those who might be more likely to have severe illness from COVID-19. Learn more about steps you can take.


Disclaimer: Articles listed in Hot Topics of the Day are selected by Public Health Genomics Branch to provide current awareness of the scientific literature and news. Inclusion in the update does not necessarily represent the views of the Centers for Disease Control and Prevention nor does it imply endorsement of the article's methods or findings. CDC and DHHS assume no responsibility for the factual accuracy of the items presented. The selection, omission, or content of items does not imply any endorsement or other position taken by CDC or DHHS. Opinion, findings and conclusions expressed by the original authors of items included in the Clips, or persons quoted therein, are strictly their own and are in no way meant to represent the opinion or views of CDC or DHHS. References to publications, news sources, and non-CDC Websites are provided solely for informational purposes and do not imply endorsement by CDC or DHHS.
TOP