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Hot Topics of the Day|PHGKB
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06/02/2020

Hot Topics of the Day are picked by experts to capture the latest information and publications on public health genomics and precision health for various diseases and health topics. Sources include published scientific literature, reviews, blogs and popular press articles.

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Archived Hot Topics of the Day By Date

Real time monitoring of COVID−19 outbreak using mobility trend data for Tokyo and Osaka, Japan
J Kurita et al, MEDRXIV, May 1, 2020

Just Stop the Superspreading-In our study, 20 percent of Covid-19 cases accounted for 80 percent of transmissions.
DC Adam, et al, NY Times, June 2, 2020

Mutations strengthened SARS-CoV-2 infectivity
J Chen et al, ARXIV, May 27, 2020

Pediatric COVID-19 in Southern California: clinical features and viral genetic diversity
U Pandey et al. MEDRXIV, June 1, 2020

Airborne Spread of SARS-CoV-2 and a Potential Role for Air Disinfection
EA Nardell et al, JAMA< June 1, 2020

Physical distancing, face masks, and eye protection to prevent person-to-person transmission of SARS-CoV-2 and COVID-19: a systematic review and meta-analysis
DK Chu et al, The Lancet, June 1, 2020

The findings support physical distancing of 1 m or more and provide quantitative estimates for models and contact tracing to inform policy. Optimum use of face masks, respirators, and eye protection in public and health-care settings should be informed by these findings and contextual factors.

Sex and gender differences and biases in artificial intelligence for biomedicine and healthcare
D Cirillo et al, NPJ Digital Medicine, June 1, 2020

Most of the currently used biomedical AI technologies do not account for bias detection. In this review we examine the current sex and gender gaps in a subset of biomedical technologies used in relation to Precision Medicine. We provide recommendations to optimize their utilization to improve the global health and disease landscape and decrease inequalities.

Association of Neighborhood Disadvantage in Childhood With DNA Methylation in Young Adulthood
A Reuben et al, JAMA Network Open, June 1, 2020

The Role of Neighborhood Social Characteristics on the Epigenome—Why the Lack of Investigations?
EC Dunn, JAMA Network Open, June 1, 2020

Research to bring together multiple levels of analysis is critical because it can inform both etiological understanding and the design of interventions or policy approaches. Yet, few attempts have been made to systematically bridge these levels in empirical analyses.

The Inflated Promise of Genomic Medicine- COVID-19 has laid bare the need to reconsider the hope and money we invest in genetics research.
E Parens, Scientific American Blog, June 1, 2020

Recalibration is not abandonment. In the midst of the crisis, genetics-based research tools offer some rare opportunities for optimism. They make it possible to track the spread of the virus and to test for the presence of the virus in individuals, and they may help to create a vaccine that will protect the health of all of us.

Familial Hypercholesterolemia: Cardiovascular Risk Stratification and Clinical Management
J Kolominsky et al, ACC, June 1, 2020

FH is an underdiagnosed yet treatable disorder. Recognizing FH is of utmost importance due to the high risk of premature CAD and major adverse cardiovascular events. After diagnosis of an index case, there is a mandate to perform cascade lipid and/or genetic screening of all first-degree relatives.


Disclaimer: Articles listed in Hot Topics of the Day are selected by Public Health Genomics Branch to provide current awareness of the scientific literature and news. Inclusion in the update does not necessarily represent the views of the Centers for Disease Control and Prevention nor does it imply endorsement of the article's methods or findings. CDC and DHHS assume no responsibility for the factual accuracy of the items presented. The selection, omission, or content of items does not imply any endorsement or other position taken by CDC or DHHS. Opinion, findings and conclusions expressed by the original authors of items included in the Clips, or persons quoted therein, are strictly their own and are in no way meant to represent the opinion or views of CDC or DHHS. References to publications, news sources, and non-CDC Websites are provided solely for informational purposes and do not imply endorsement by CDC or DHHS.
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