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Hot Topics of the Day|PHGKB
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02/04/2020

Hot Topics of the Day are picked by experts to capture the latest information and publications on public health genomics and precision health for various diseases and health topics. Sources include published scientific literature, reviews, blogs and popular press articles.

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David Vetter was ‘the boy in the bubble.’ His short life provided insights into how the rare disorder SCID works.
E Blakemore, Washington Post, January 2020

David’s short life also provided insights into how SCID works. Better bone marrow screening now means more transplants are successful. According to the Immune Deficiency Foundation, 91 percent of infants who are diagnosed early and given transplants by age 3½ months survive

Innovation without integration
AB Cohen et al, NPJ Digital Medicine, February 3, 2020

We believe prevention-focused digital health technologies are currently most able to avoid integration with the existing healthcare system. This is in line with digital health trends we observe, whereby prevention products directly appeal to consumers outside their normal experience within the healthcare system.

Beyond validation: getting health apps into clinical practice
WJ Gordon et al, NPJ DIiital Medicine, February 3, 2020

We propose a framework for prescribing apps and outline the key issues that need to be addressed to enable app dissemination in clinical care. This includes: education and awareness, creating digital formularies, workflow and EHR integration, payment models, and patient/provider support.

Communication, collaboration and cooperation can stop the 2019 coronavirus
Nature Medicine, February 3, 2020

As the outbreak of a deadly new coronavirus in China and its rapid spread is rattling countries, only the collective international experience and advances derived from past outbreaks can accelerate its control.

A new coronavirus associated with human respiratory disease in China
F Wu et al. Nature, February 3, 2020

Epidemiological investigation suggested that the outbreak was associated with a seafood market. Metagenomic RNA sequencing of a bronchoalveolar lavage fluid sample identified a novel RNA virus from the family Coronaviridae. Phylogenetic analysis revealed that the virus was most closely related to a group of SARS-like coronaviruses from bats in China.


Disclaimer: Articles listed in Hot Topics of the Day are selected by Public Health Genomics Branch to provide current awareness of the scientific literature and news. Inclusion in the update does not necessarily represent the views of the Centers for Disease Control and Prevention nor does it imply endorsement of the article's methods or findings. CDC and DHHS assume no responsibility for the factual accuracy of the items presented. The selection, omission, or content of items does not imply any endorsement or other position taken by CDC or DHHS. Opinion, findings and conclusions expressed by the original authors of items included in the Clips, or persons quoted therein, are strictly their own and are in no way meant to represent the opinion or views of CDC or DHHS. References to publications, news sources, and non-CDC Websites are provided solely for informational purposes and do not imply endorsement by CDC or DHHS.
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