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Health Equity PHGKB

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Last Posted: Oct 15, 2021
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Special focus issue on epigenomics and health disparities: foreword.
Argentieri M Austin et al. Epigenomics 2021 10

Although epigenomic researchers have been investigating the influences of physical environmental exposures (e.g., air pollution, contaminants and heavy metal exposures and lifestyle factors such as smoking, alcohol and nutrition) on epigenetic mechanisms for years under the banner of ‘environmental epigenomics’, the field is at a crossroads where a fundamental rethinking of what constitutes a human environment is necessary, especially in the pursuit of understanding disparities in health and disease. It will be crucial for the field of environmental epigenomics to expand its inquiry to the entire exposome (i.e., all nongenetic influences on health, including social, economic, cultural, built environment and housing and psychosocial dimensions of life) in order to truly come to terms with the determinants of health inequality from an epigenomic perspective.

National-Level Disparities in Internet Access Among Low-Income and Black and Hispanic Youth: Current Population Survey.
Dolcini M Margaret et al. Journal of medical Internet research 2021 10 (10) e27723

Internet access increased from 2015 to 2017, but socioeconomic status (SES) and racial and ethnic disparities remained. In 2017, the greatest disparities were found for youth in low-income households (no home access=23%) and for Black youth (no home access=18%) and Hispanic youth (no home access=14%). Low-income Black and Hispanic youth were the most likely to lack home internet access (no home access, low SES Black youth=29%; low SES Hispanic youth=21%). The mode of access (eg, from home and smartphone) and smartphone-only analyses also revealed disparities.

Monitoring sociodemographic inequality in COVID-19 vaccination coverage in England: a national linked data study
T Dolby et al, MEDRXIV, October 7,2021

Our study population included 35,223,466 adults. A lower percentage of males than females were vaccinated in the young and middle age groups (18-59 years) but not in the older age groups. Vaccination rates were highest among individuals of White British and Indian ethnic backgrounds and lowest among Black Africans (aged =80 years) and Black Caribbeans (18-79 years). Differences by ethnic group emerged as soon as vaccination roll-out commenced and widened over time. Vaccination rates were also lower among individuals who identified as Muslim, lived in more deprived areas, reported having a disability, did not speak English as their main language, lived in rented housing, belonged to a lower socio-economic group.

Health Equity and Disability
CDC COVID Data Tracker, October 8, 2021

COVID-19 cases, hospitalizations, and deaths are once again declining in many parts of the country. Sadly, the United States reached a grim milestone this week, surpassing 700,000 total deaths from COVID-19. Studies have shown that COVID-19 does not affect all population groups equally. Some people with disabilities might be more likely to get infected or have severe outcomes from COVID-19 because of underlying medical conditions, group living settings, or systemic health and social inequities.


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Health Equity and Disability
CDC COVID Data Tracker, October 8, 2021
Monitoring sociodemographic inequality in COVID-19 vaccination coverage in England: a national linked data study External Web Site Icon
T Dolby et al, MEDRXIV, October 7,2021
The Effect of COVID-19 on Anxiety Levels of Children with CF and Healthy Peers. External Web Site Icon
Yanaz Muruvvet, et al. Pediatrics international : official journal of the Japan Pediatric Society 2021 0 0.
Heterogeneous Effects of Health Insurance on Rural Children's Health in China: A Causal Machine Learning Approach. External Web Site Icon
Chen Hua et al. International journal of environmental research and public health 2021 18(18)
Quantifying representativeness in randomized clinical trials using machine learning fairness metrics. External Web Site Icon
Qi Miao et al. JAMIA open 2021 4(3) ooab077
Association of Patient Characteristics With Delivery of Ophthalmic Telemedicine During the COVID-19 Pandemic. External Web Site Icon
Aziz Kanza et al. JAMA ophthalmology 2021 9
Impact of sickle cell trait on morbidity and mortality from SARS-CoV-2 infection. External Web Site Icon
Merz Lauren E, et al. Blood advances 2021 0 0. (18) 3690-3693
Influence of social determinants of health and county vaccination rates on machine learning models to predict COVID-19 case growth in Tennessee. External Web Site Icon
Wylezinski Lukasz S, et al. BMJ health & care informatics 2021 0 0. (1)
The Problem of Fairness in Synthetic Healthcare Data. External Web Site Icon
Bhanot Karan, et al. Entropy (Basel, Switzerland) 2021 0 0. (9)
Analysis of Population Differences in Digital Conversations About Cancer Clinical Trials: Advanced Data Mining and Extraction Study. External Web Site Icon
Perez Edith A et al. JMIR cancer 2021 7(3) e25621
Equitable Implementation of Artificial Intelligence in Medical Imaging: What Can be Learned from Implementation Science? External Web Site Icon
Yousefi Nooraie Reza et al. PET clinics 2021 16(4) 643-653
Social Determinants in Machine Learning Cardiovascular Disease Prediction Models: A Systematic Review. External Web Site Icon
Zhao Yuan et al. American journal of preventive medicine 2021 61(4) 596-605
‘Delta has been brutal’: Covid-19 variant is decimating rural areas already reeling from the pandemic External Web Site Icon
O Goldhill, Stat News, September 21, 2021
Evaluating Primary Care Providers' Readiness for Delivering Genetic and Genomic Services to Underserved Populations. External Web Site Icon
Sharma Yashoda et al. Public health genomics 2021 1-10
Genetically determined low income modifies Alzheimer's disease risk. External Web Site Icon
Wang Rong-Ze et al. Annals of translational medicine 2021 9(15) 1222
Effectiveness of mRNA Covid-19 Vaccine among U.S. Health Care Personnel. External Web Site Icon
Pilishvili Tamara et al. The New England journal of medicine 2021 9
Human genetic basis of coronavirus disease 2019. External Web Site Icon
Deng Hao, et al. Signal transduction and targeted therapy 2021 0 0. (1) 344
Robust immune response to the BNT162b mRNA vaccine in an elderly population vaccinated 15 months after recovery from COVID-19. External Web Site Icon
Lee Hye Kyung, et al. medRxiv : the preprint server for health sciences 2021 0 0.
Ethics, Integrity and Retributions of Digital Detection Surveillance Systems on Infectious Diseases: Systematic literature review. External Web Site Icon
Zhao Yan Ivy, et al. Journal of medical Internet research 2021 0 0.
Experimental Technologies in the Diagnosis and Treatment of COVID-19 in Patients with Comorbidities. External Web Site Icon
Amin Md Shahnoor, et al. Journal of healthcare informatics research 2021 0 0. 1-24

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Disclaimer: Articles listed in the Public Health Knowledge Base are selected by the CDC Office of Public Health Genomics to provide current awareness of the literature and news. Inclusion in the update does not necessarily represent the views of the Centers for Disease Control and Prevention nor does it imply endorsement of the article's methods or findings. CDC and DHHS assume no responsibility for the factual accuracy of the items presented. The selection, omission, or content of items does not imply any endorsement or other position taken by CDC or DHHS. Opinion, findings and conclusions expressed by the original authors of items included in the update, or persons quoted therein, are strictly their own and are in no way meant to represent the opinion or views of CDC or DHHS. References to publications, news sources, and non-CDC Websites are provided solely for informational purposes and do not imply endorsement by CDC or DHHS.

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