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Hot Topics of the Day are picked by experts to capture the latest information and publications on public health genomics and precision health for various diseases and health topics. Sources include published scientific literature, reviews, blogs and popular press articles.

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109 hot topic(s) found with the query "Nutrition"

The past 10 years of cystic fibrosis treatment: the road to cure.
Claudio Castaños et al. Lancet Respir Med 2023 10 (10) 864-865 (Posted: Oct 23, 2023 7PM)

From the paper: " Cystic fibrosis is a genetic disease associated with high rates of premature death. There have been many advances in clinical care for cystic fibrosis during the past 50 years, such as the widespread implementation of newborn screening for early diagnosis, enhanced mucociliary clearance techniques, and improvements in nutrition (including adjusted pancreatic enzyme replacement therapy and a high-energy, high-fat diet). However, the life expectancy of patients with cystic fibrosis is still substantially shorter than that of the general population."

NIH launches largest precision nutrition research effort of its kind
NIH ALL of Us, May 2023 Brand (Posted: May 17, 2023 11AM)

The National Institutes of Health is now enrolling participants in a landmark initiative to advance nutrition research. Nutrition for Precision Health, powered by the All of Us Research Program (NPH), is working with 14 sites across the United States to engage 10,000 participants from diverse backgrounds and learn more about how our bodies respond differently to food. NPH will use artificial intelligence (AI)-based approaches to analyze information provided by participants in order to develop algorithms that predict responses to dietary patterns. The study’s findings may one day allow healthcare providers to offer more customized nutritional guidance to improve overall health.

A review of the Mediterranean diet and nutritional genomics in relation to cancer in women.
Gulten Tuncel et al. Journal of preventive medicine and hygiene 2022 12 (2 Suppl 3) E81-E86 (Posted: Mar 02, 2023 10AM)

Genetics, genomics, and diet interactions in obesity in the Latin American environment.
Patricia Guevara-Ramírez et al. Frontiers in nutrition 2022 12 1063286 (Posted: Mar 02, 2023 10AM)

Workshop on Considerations for Returning Individual Genomic Results from Population-Based Surveys: Focus on the National Health and Nutrition Examination Survey
National Academy of Medicine Workshop, December 2022 (Posted: Oct 20, 2022 10AM)

Population surveys collect information from participants by asking questions. Today, many surveys also collect biologic specimens that can be used to analyze a respondent's DNA and other biomarkers. The National Health and Nutrition Examination Survey (NHANES) administers a physical examination, collects biospecimens, and reports some test results (e.g., cholesterol levels) to the participant. Traditionally, NHANES participants have been told that they will not be contacted with personal genetic results. However, clinical science is evolving to encourage more return of individual research results. Therefore, NHANES will revisit the issue of if, when, and how to return genetic results to study participants.

Rethinking healthy eating in light of the gut microbiome
AM Armet et al, Cell Host and Microbe, June 8, 2022 (Posted: Jun 09, 2022 11AM)

In this review, we discuss contemporary nutritional recommendations from a microbiome science perspective, focusing on mechanistic evidence that established host-microbe interactions as mediators of the physiological effects of diet. We apply this knowledge to inform discussions of nutrition controversies, advance innovative dietary strategies, and propose an experimental framework that integrates the microbiome into nutrition research. The congruence of key paradigms in the nutrition and microbiome disciplines validates current recommendations in dietary guidelines, and the systematic incorporation of microbiome science into nutrition research has the potential to further improve and innovate healthy eating.

Estimated Yield of Screening for Heterozygous Familial Hypercholesterolemia With and Without Genetic Testing in US Adults
BK Bellows et al, JAHA, May 18, 2022 (Posted: May 19, 2022 10AM)

Individual clinical and genotype data from the UK Biobank were used to estimate the probability of any likely pathogenic familial hypercholesterolemia (FH) genetic variants. Dutch Lipid Clinic Network clinical criteria and the estimated probability of FH were applied to National Health and Nutrition Examination Survey participants to estimate the yield of FH screening in US adults. Clinical criteria-based screening alone could identify 3.7 FH cases per 1000 US adults screened, and adding genetic testing could increase this to 6.6 FH cases per 1000 adults screened.

Personalized Dietary Recommendations Based on Lipid-Related Genetic Variants: A Systematic Review.
Pérez-Beltrán Yolanda E et al. Frontiers in nutrition 2022 4 830283 (Posted: Apr 23, 2022 9AM)

Findings included in this systematic review indicated that a certain percentage of dietary macronutrients, the consumption of specific amounts of polyunsaturated or monounsaturated fatty acids, as well as the ingestion of nutraceuticals or dietary supplements could be considered as potential strategies for the development of a wide range of nutrigenetic interventions since they have a direct impact on the blood levels of lipids.

Here Come the Artificial Intelligence Nutritionists- Companies are experimenting with personalized diet apps, saying the future of healthy eating is A.I.
S Ravindran, NY Times, March 14, 2022 (Posted: Mar 16, 2022 0PM)

The field of personalized nutrition is still in its Wild West phase, and experts say it’s important to sort through the hype. Many companies are willing to test your microbiome and offer A.I.-driven dietary recommendations — as well as sell you supplements — but few are based on scientifically rigorous trials.

Epigenetics: An Emerging Tool for Health Equity Science
E Drzymalla et al, CDC Blog Post, March 8, 2022 Brand (Posted: Mar 08, 2022 10AM)

The biological connections between SDOH and adverse health outcomes are not fully understood. Could the field of epigenetics help us gain better insight into these connections? Epigenetics involves biological processes such as DNA methylation or histone modification that do not change the genome sequence but alter gene expression. Epigenetic markers have been shown to be affected by natural, built, and social environmental exposures such as nutrition, stress, and air pollution. Epigenetic markers may shed light on potential causal links between SDOH and adverse health outcomes and are potentially modifiable, providing new approaches to therapeutics (e.g., cancer).

Precision Public Health in Action: New CDC Pilot Projects Integrating Human Genomics into Public Health Surveillance and Applied Research
M Clyne et al, CDC Blog Post, February 14, 2022 Brand (Posted: Feb 15, 2022 7AM)

Six CDC projects were selected for funding in 2022 and 2023. They cover a wide range of topics, including: Assessing the impact of genetics in the control of two infectious diseases (Tuberculosis and Ebola), enhancing the reporting of gene/genome sequencing in newborn screening programs, examining the role of medications and genetics in the National Birth Defects Prevention Study (NBDPS), establishing population-based, ethnicity-specific allele frequencies for pharmacogenomic traits of public health importance using the National Health and Nutrition Examination Survey (NHANES), and enhancing the evaluation of genetic risk prediction models for inhibitor development among people with hemophilia in different populations.

NIH awards $170 million for precision nutrition study
NIH, January 20, 2022 Brand (Posted: Jan 21, 2022 7AM)

A major challenge in precision nutrition is the inability to combine the many factors that affect how individuals respond to diet into a personalized nutrition regimen. These potential factors include the microbiome—the community of microbes that live in our gut—metabolism, nutritional status, genetics, and the environment. The way these factors interact to affect health are still poorly understood. To address these gaps, NPH will collect new data on multiple potential predictive factors and combine it with existing data in the All of Us database to develop a more complete picture of how individuals respond to different foods or dietary routines.

The unique challenges of studying the genetics of diet and nutrition
J Merino et al, Nature Medicine, January 3, 2022 (Posted: Jan 05, 2022 9AM)

Epidemiologists increasingly embrace Mendelian randomization (MR), a methodological approach that uses genetic variation associated with modifiable exposures as instrumental variables to infer causal relationships between exposure and outcome1. A genotype that determines intake of a specific food or nutrient, randomly assigned at meiosis, could circumvent error and confounding of traditional epidemiologic methods. Could MR therefore be a route to redemption for nutrition science?

Special focus issue on epigenomics and health disparities: foreword.
Argentieri M Austin et al. Epigenomics 2021 10 (Posted: Oct 15, 2021 10AM)

Although epigenomic researchers have been investigating the influences of physical environmental exposures (e.g., air pollution, contaminants and heavy metal exposures and lifestyle factors such as smoking, alcohol and nutrition) on epigenetic mechanisms for years under the banner of ‘environmental epigenomics’, the field is at a crossroads where a fundamental rethinking of what constitutes a human environment is necessary, especially in the pursuit of understanding disparities in health and disease. It will be crucial for the field of environmental epigenomics to expand its inquiry to the entire exposome (i.e., all nongenetic influences on health, including social, economic, cultural, built environment and housing and psychosocial dimensions of life) in order to truly come to terms with the determinants of health inequality from an epigenomic perspective.

NIH's ‘precision nutrition’ bet aims for individualized diets
J Kaiser, Science, February 5, 2021 (Posted: Feb 06, 2021 7AM)

There's no one-size-fits-all diet. If you want to avoid spiking your blood sugar with a snack, a banana may seem like a better choice than a sugary cookie. “We all know people who lose weight easily, and others who don't.” Now, the U.S. National Institutes of Health is making a major push to understand these individual differences.

Nutrigenomics: lessons learned and future perspectives.
Brennan Lorraine et al. The American journal of clinical nutrition 2021 Jan (Posted: Jan 31, 2021 0PM)

Although many of the nutrigenomic studies performed to date were labelled as proof-of-concept or pilot studies, there is ample evidence to support the use of these technologies in nutrition science. Incorporating omic technologies from the start of study designs will ensure that studies are sufficiently powered for such data.

Precision Nutrition: Research Gaps and Opportunities Workshop
NIH Workshop, January 11-12, 2021 Brand (Posted: Jan 05, 2021 8AM)

Precision nutrition science enables individualized dietary recommendations or therapies based on these factors. This workshop will bring together scientists with diverse expertise to explore how best to address these complex factors. It also will focus on diet-related chronic diseases and how artificial intelligence (AI) and deep-learning techniques may be used to generate individualized dietary recommendations and algorithms.

Clinical Implications of Removing Race From Estimates of Kidney Function.
Diao James A et al. JAMA 2020 Dec (Posted: Dec 04, 2020 11AM)

In this population-based study, we found that removal of race adjustment may increase chronic kidney disease diagnoses among Black adults and enhance access to specialist care, medical nutrition therapy, kidney disease education, and kidney transplantation, while potentially excluding kidney donors and prompting drug contraindications or dose reductions for individuals reclassified to advanced stages of CKD.

Could nutrition modulate COVID-19 susceptibility and severity of disease? A systematic review
PT James et al, MEDRXIV, October 21, 2020 (Posted: Oct 22, 2020 9AM)

Polygenic Contribution to Low-density Lipoprotein Cholesterol Levels and Cardiovascular Risk in Monogenic Familial Hypercholesterolemia
M Trinder et al. Cir Genomics Precision Medicine, August 2020 (Posted: Aug 14, 2020 7AM)

We constructed a weighted LDL-C polygenic score, composed of 28 single-nucleotide variants, for individuals with monogenic FH from the British Columbia FH; Nutrition, Metabolism and Atherosclerosis Clinic; and UK Biobank cohorts. Polygenic contributions to LDL-C explain some of the heterogeneity in clinical presentation and ASCVD risk for individuals with FH.

Precision Nutrition-the Answer to "What to Eat to Stay Healthy".
Rodgers Griffin P et al. JAMA 2020 Aug (Posted: Aug 08, 2020 10AM)

Many studies have revealed profound differences among individuals in disease risk and biological responses to diet, making it challenging to fully answer this question. This necessitates moving beyond a one-size-fits-all dietary prescription for optimal health and disease prevention.

Dietary RNA is ripe for investigation
K Witwer, Nature Outlook, June 17, 2020 (Posted: Jun 22, 2020 9AM)

Opportunities abound to study whether dietary RNA is delivered to the cells of the alimentary tract and the microbes that live there. These investigations must include appropriate controls to determine whether dietary extracellular RNA is mostly a source of nutrition in the form of molecular building blocks.

NIH releases strategic plan to accelerate nutrition research over next 10 years
NIH, May 27, 2020 Brand (Posted: Jun 01, 2020 8AM)

What if each of us had individualized dietary recommendations that helped us decide what, when, why, and how to eat to optimize our health and quality of life? This precision nutrition approach — developing targeted and effective diet interventions in a diverse population — is among the ambitious goals set out by the 2020-2030 Strategic Plan

Contribution of macronutrients to obesity: implications for precision nutrition
Nat Rev Endrocrinology, March 31, 2020 (Posted: Apr 04, 2020 9AM)

the interactions of the genetic make-up and/or microbiota features of a person with specific macronutrient intakes or dietary pattern consumption help to explain individualized responses to macronutrients and food patterns, which might represent key factors for comprehensive precision nutrition recommendations.

Automatic, wearable-based, in-field eating detection approaches for public health research: a scoping review
BM Bell, NPJ Digital Health, March 13, 2020 (Posted: Mar 14, 2020 6AM)

This scoping review highlights the current state of wearable sensors’ ability to improve upon traditional eating assessment methods by passively detecting eating activity in naturalistic settings, over long periods of time, and with minimal user interaction.

Personalized Nutrition: The Latest on DNA-Based Diets
Scientific American, September 27, 2019 (Posted: Oct 01, 2019 8AM)

Since the sequencing of the human genome, there's been a lot of interest in nutrigenomics. It’s long been clear that we don’t all respond the same way to the same dietary interventions. Some people do really well on a higher fat diet. Others develop high triglycerides or cholesterol on the same diet.

‘Precision nutrition’ may be on the horizon, but large-scale, definitive trials lacking
LL Peterson, Healio, Sepetmber 10, 2019 (Posted: Sep 12, 2019 7AM)

Nutrigenetics and NutrigenomicsApproaches for Nutrition Research
NIH funding Announcement, September 2019 Brand (Posted: Sep 12, 2019 7AM)

The Food Programme, Is There A Perfect Diet Just For You? The Future of Personalised Nutrition
BBC Radio 4 (Posted: Jul 15, 2019 1PM)

Prevalence and Cardiovascular Health Impact of Family History of Premature Heart Disease in the United States: Analysis of the National Health and Nutrition Examination Survey, 2007–2014
Mooneshinghe R, et al. Journal of the American Heart Association. 2019;8 (Posted: Jul 15, 2019 9AM)

This CDC paper used population based nationally representative data to estimate the prevalence and public health impact of family history of premature heart disease (under age 50 years). The study shows that family history is common affecting millions of people, and is associated with higher prevalence of heart disease and modifiable heart disease risk factors.

Precision Nutrition and the Microbiome Part II: Potential Opportunities and Pathways to Commercialization
S Mills et al, MDPI open access, June 27, 2019 (Posted: Jun 27, 2019 10AM)

Modulation of the human gut microbiota is a recognized strategy to improve health and prevent disease. Yet we are only beginning to understand the health impact of these interventions on the gut microbiota. Microbiome composition can potentially serve as a biomarker to predict responsiveness to interventions, diets and dietary components enabling greater opportunities for its use towards disease prevention and health promotion, forging the way towards evidence-based scientific validation.

Diet for One? Scientists Stalk the Dream of Personalized Nutrition- No single food regimen works for everyone. A new study is the most comprehensive effort yet to understand why.
C Graber et al, NY Times, June 10, 2019 (Posted: Jun 10, 2019 10AM)

Nutrigenetic Testing for Personalized Nutrition: An Evaluation of Public Perceptions, Attitudes, and Concerns in a Population of French Canadians.
Vallée Marcotte Bastien et al. Lifestyle genomics 2019 May 1-8 (Posted: May 29, 2019 8AM)

Primers on nutrigenetics and nutri(epi)genomics: Origins and development of precision nutrition.
Bordoni Laura et al. Biochimie 2019 Mar 160156-171 (Posted: Mar 20, 2019 9AM)

Sport Nutrigenomics: Personalized Nutrition for Athletic Performance.
Guest Nanci S et al. Frontiers in nutrition 2019 8 (Posted: Mar 11, 2019 9AM)

Genetic background, nutrition and obesity: a review.
Vettori A et al. European review for medical and pharmacological sciences 2019 Feb (4) 1751-1761 (Posted: Mar 11, 2019 9AM)

Good Nutrition Starts Early
CDC, 2019 Brand (Posted: Mar 04, 2019 2PM)

Adults with familial hypercholesterolaemia have healthier dietary and lifestyle habits compared with their non-affected relatives: the SAFEHEART study.
Arroyo-Olivares Raquel et al. Public health nutrition 2019 Feb 1-11 (Posted: Feb 12, 2019 10AM)

From nutrigenomics to personalizing diets: are we ready for precision medicine?
Loos Ruth J F et al. The American journal of clinical nutrition 2019 Jan (1) 1-2 (Posted: Feb 06, 2019 8AM)

Personalised nutrition and health.
Ordovas Jose M et al. BMJ (Clinical research ed.) 2018 06 bmj.k2173 (Posted: Oct 31, 2018 8AM)

Your DNA, Your Diet: How Nutrition Is Being Personalized At-home tests are helping people learn more about their bodies, but the science is still evolving
C Ostroff, WSJ, August 30, 2018 (Posted: Aug 31, 2018 11AM)

Nutrigenomics and the Future of Nutrition: Proceedings of a Workshop.
National Academies of Sciences, Engineering, and Medicine; Health and Medicine Division; Food and Nutrition Board; Food Forum, 2018 (Posted: Aug 24, 2018 9AM)

Associations between Single Nucleotide Polymorphisms and Total Energy, Carbohydrate, and Fat Intakes: A Systematic Review.
Drabsch Theresa et al. Advances in nutrition (Bethesda, Md.) 2018 Jul (4) 425-453 (Posted: Jul 23, 2018 11AM)

Genetic effects on bone health.
Lovšin Nika et al. Current opinion in clinical nutrition and metabolic care 2018 Jul (4) 233-239 (Posted: Jul 02, 2018 8AM)

Precision nutrition for prevention and management of type 2 diabetes.
Wang Dong D et al. The lancet. Diabetes & endocrinology 2018 May (5) 416-426 (Posted: Apr 27, 2018 9AM)

Nutritional Genomics and Direct-to-Consumer Genetic Testing: An Overview.
Guasch-Ferré Marta et al. Advances in nutrition (Bethesda, Md.) 2018 Mar 9(2) 128-135 (Posted: Apr 18, 2018 10AM)

Nutritional Status the First Two Years of Life in Cystic Fibrosis Diagnosed by Newborn Screening.
Munck Anne et al. Journal of pediatric gastroenterology and nutrition 2018 Mar (Posted: Mar 21, 2018 4PM)

The Evolving Role of Multivitamin/Multimineral Supplement Use among Adults in the Age of Personalized Nutrition.
Blumberg Jeffrey B et al. Nutrients 2018 Feb (2) (Posted: Mar 11, 2018 1PM)

Precision Nutrition and Type 2 Diabetes Management: Is It Ready for Prime Time?
Harvard School of Public Health, Feb 2018 (Posted: Feb 13, 2018 9AM)

The contribution of family history to the burden of diagnosed diabetes, undiagnosed diabetes, and prediabetes in the United States: analysis of the National Health and Nutrition Examination Survey, 2009–2014.
Moonesinghe R, et al. Genetics in Medicine, Jan 25, 2018 (Posted: Jan 25, 2018 1PM)

Gene-nutrient interactions and susceptibility to human obesity.
Castillo Joseph J et al. Genes & nutrition 2017 29 (Posted: Jan 13, 2018 0PM)

Genetic Risk Factors for Folate-Responsive Neural Tube Defects.
Molloy Anne M et al. Annual review of nutrition 2017 Aug 269-291 (Posted: Jan 08, 2018 0PM)

Proposed guidelines to evaluate scientific validity and evidence for genotype-based dietary advice
KA Grimaldi et al, Genes and Nutrition, Dec 2017 (Posted: Dec 29, 2017 11AM)

Opportunities for training for nutritional professionals in nutritional genomics: What is out there?
Collins Jorja et al. Nutrition & dietetics: the journal of the Dietitians Association of Australia 2017 Dec (Posted: Dec 20, 2017 0PM)

The role of epigenetics in cardiovascular health and aging: a focus on physical activity and nutrition.
Wallace Robert G et al. Mechanisms of ageing and development 2017 Nov (Posted: Dec 10, 2017 10AM)

Scientific Evidence for Personalized Nutrition: Ethical Implications of Methological Limitations
C Jannsens, Slide Presentation, Dec 2017 (Posted: Dec 06, 2017 11AM)

The future of nutrition: Nutrigenomics and nutrigenetics in obesity and cardiovascular diseases.
Peña-Romero Alicia Cristina et al. Critical reviews in food science and nutrition 2017 Jul 1-12 (Posted: Nov 07, 2017 9AM)

Nutrigenetics and Nutrigenomics Approaches for Nutrition Research
NIH Funding Opportunity, Nov 2017 (Posted: Nov 07, 2017 9AM)

Nutrition, Genes, and Age-Related Macular Degeneration: What Have We Learned from the Trials?
Chew Emily Y et al. Ophthalmologica. Journal international d'ophtalmologie. International journal of ophthalmology. Zeitschrift fur Augenheilkunde 2017 238(1-2) 1-5 (Posted: Oct 04, 2017 10AM)

Epigenetic Matters: The Link between Early Nutrition, Microbiome, and Long-term Health Development
F Andrio et al, Front Pediatrics, Aug 2017 (Posted: Sep 14, 2017 3PM)

Nature, Nurture, and Cancer Risks: Genetic and Nutritional Contributions to Cancer.
Theodoratou Evropi et al. Annual review of nutrition 2017 Aug 293-320 (Posted: Sep 01, 2017 8AM)

Obesity and microbiota: an example of an intricate relationship.
Duranti Sabrina et al. Genes & nutrition 2017 18 (Posted: Jul 17, 2017 8AM)

Epigenetics, nutrition and mental health. Is there a relationship?
Stevens Aaron J et al. Nutritional neuroscience 2017 May 1-12 (Posted: Jul 12, 2017 6PM)

Guide for Current Nutrigenetic, Nutrigenomic, and Nutriepigenetic Approaches for Precision Nutrition Involving the Prevention and Management of Chronic Diseases Associated with Obesity.
Ramos-Lopez Omar et al. Journal of nutrigenetics and nutrigenomics 2017 Jul 10(1-2) 43-62 (Posted: Jul 12, 2017 11AM)

The effect of the apolipoprotein E genotype on response to personalized dietary advice intervention: findings from the Food4Me randomized controlled trial.
Fallaize Rosalind et al. The American journal of clinical nutrition 2016 Sep 104(3) 827-36 (Posted: Jun 07, 2017 9AM)

Gene-Diet Interaction and Precision Nutrition in Obesity.
Heianza Yoriko et al. International journal of molecular sciences 2017 Apr (4) (Posted: May 30, 2017 7AM)

Genetics of fat intake in the determination of body mass.
Chmurzynska Agata et al. Nutrition research reviews 2017 Mar 1-12 (Posted: Apr 18, 2017 10AM)

Translation of Nutritional Genomics into Nutrition Practice: The Next Step.
Murgia Chiara et al. Nutrients 2017 Apr 9(4) (Posted: Apr 12, 2017 8AM)

Precision nutrition: Hype or hope?
Harvard School of Public Health, February 2017 (Posted: Mar 20, 2017 4PM)

Clinical worthlessness of genetic prediction of common forms of diabetes mellitus and related chronic complications.: A position statement of the Italian Society of Diabetology.
Buzzetti R et al. Nutrition, metabolism, and cardiovascular diseases : NMCD 2016 Aug (Posted: Jan 11, 2017 9AM)

"Personalized nutrition” isn’t going to solve our diet problems
J Belluz, Vox, November 2, 2016 (Posted: Nov 02, 2016 0PM)

Nutrigenomics at the Interface of Aging, Lifespan, and Cancer Prevention.
Riscuta Gabriela et al. The Journal of nutrition 2016 Oct (10) 1931-1939 (Posted: Oct 10, 2016 7PM)

Recent Findings in Alzheimer Disease and Nutrition Focusing on Epigenetics.
Athanasopoulos Dimitrios et al. Advances in nutrition (Bethesda, Md.) 2016 Sep (5) 917-27 (Posted: Sep 19, 2016 1PM)

Coffee Consumption Is Positively Associated with Longer Leukocyte Telomere Length in the Nurses' Health Study.
Liu Jason J et al. The Journal of nutrition 2016 Jul (7) 1373-8 (Posted: Jul 13, 2016 7AM)

Guide and Position of the International Society of Nutrigenetics/Nutrigenomics on Personalised Nutrition: Part 1 - Fields of Precision Nutrition.
Ferguson Lynnette R et al. Journal of nutrigenetics and nutrigenomics 2016 May 9(1) 12-27 (Posted: May 18, 2016 10AM)

Future Perspectives of Personalized Weight Loss Interventions Based on Nutrigenetic, Epigenetic, and Metagenomic Data.
Goni Leticia et al. The Journal of nutrition 2016 Mar (Posted: Mar 11, 2016 6AM)

Could a diet tailored to your DNA save your life
A Fleming, the Guardian, February 29, 2016 (Posted: Mar 02, 2016 5PM)

Nutrigenomics 2.0: The Need for Ongoing and Independent Evaluation and Synthesis of Commercial Nutrigenomics Tests' Scientific Knowledge Base for Responsible Innovation.
Pavlidis Cristiana et al. Omics : a journal of integrative biology 2016 Feb (2) 65-8 (Posted: Mar 01, 2016 0PM)

Polymorphism in the CLOCK gene may influence the effect of fat intake reduction on weight loss.
Loria-Kohen Viviana et al. Nutrition (Burbank, Los Angeles County, Calif.) 2016 Apr (4) 453-60 (Posted: Mar 01, 2016 0PM)

A nutrigenomics approach for the study of anti-aging interventions: olive oil phenols and the modulation of gene and microRNA expression profiles in mouse brain.
Luceri Cristina et al. European journal of nutrition 2015 Dec (Posted: Mar 01, 2016 0PM)

Precision Nutrition 4.0: A Big Data and Ethics Foresight Analysis-Convergence of Agrigenomics, Nutrigenomics, Nutriproteomics, and Nutrimetabolomics.
Özdemir Vural et al. Omics : a journal of integrative biology 2016 Feb (2) 69-75 (Posted: Mar 01, 2016 0PM)

Analysis of Genes Involved in Body Weight Regulation by Targeted Re-Sequencing.
Volckmar Anna-Lena et al. PloS one 2016 (2) e0147904 (Posted: Mar 01, 2016 0PM)

National Nutrition Month: Smart Nutrition 101
Brand (Posted: Mar 01, 2016 0PM)

The Role of Probiotics on the Microbiota: Effect on Obesity.
Nova Esther et al. Nutrition in clinical practice : official publication of the American Society for Parenteral and Enteral Nutrition 2016 Feb (Posted: Feb 17, 2016 5PM)

Nutrition, gut microbiota and child health outcomes.
Videhult Frida Karlsson et al. Current opinion in clinical nutrition and metabolic care 2016 Feb (Posted: Feb 17, 2016 5PM)

Microbiota in Inflammatory Bowel Disease Pathogenesis and Therapy: Is It All About Diet?
Serban Daniela Elena et al. Nutrition in clinical practice : official publication of the American Society for Parenteral and Enteral Nutrition 2015 Dec (6) 760-79 (Posted: Jan 25, 2016 10AM)

Dietary Guidelines for Americans
K deSalvo, JAMA, January 11, 2016 (Posted: Jan 12, 2016 9AM)

A Personalized Diet, Better Suited To You
K Murphy, New York Times, January 11, 2016 (Posted: Jan 12, 2016 9AM)

Personalized Nutrition by Prediction of Glycemic Responses
D Zeev et al, Cell, Nov 2015 (Posted: Jan 12, 2016 9AM)

Bringing clarity to the role of MTHFR variants in neural tube defect prevention.
Stover Patrick J et al. The American journal of clinical nutrition 2015 Jun (6) 1111-2 (Posted: Jan 11, 2016 1PM)

Personalized Nutrition by Prediction of Glycemic Responses.
Zeevi David et al. Cell 2015 Nov (5) 1079-94 (Posted: Dec 07, 2015 5PM)

Microbiome and Gluten.
Sanz Yolanda et al. Annals of nutrition & metabolism 2015 28-41 (Posted: Dec 07, 2015 5PM)

The gut microbiome, diet, and links to cardiometabolic and chronic disorders.
Aron-Wisnewsky Judith et al. Nature reviews. Nephrology 2015 Nov (Posted: Dec 07, 2015 5PM)

Disentangling type 2 diabetes and metformin treatment signatures in the human gut microbiota.
Forslund Kristoffer et al. Nature 2015 Dec (Posted: Dec 07, 2015 5PM)

Mechanisms of Microbe-Host Interaction in Crohn's Disease: Dysbiosis vs. Pathobiont Selection.
Buttó Ludovica F et al. Frontiers in immunology 555 (Posted: Dec 07, 2015 5PM)

Microbiota-based nutrition plans
C Nunes-Alves, Nature Reviews Microbiology, December 7, 2015 (Posted: Dec 07, 2015 5PM)

Systems biology approaches to study the molecular effects of caloric restriction and polyphenols on aging processes.
Lacroix Sébastien et al. Genes & nutrition 2015 Nov (6) 58 (Posted: Dec 03, 2015 8PM)

Transgenerational epigenetic inheritance of diabetes risk as a consequence of early nutritional imbalances.
Jimenez-Chillaron Josep C et al. The Proceedings of the Nutrition Society 2015 Nov 1-12 (Posted: Nov 23, 2015 9AM)

Extensive Modulation of the Fecal Metagenome in Children With Crohn's Disease During Exclusive Enteral Nutrition.
Quince Christopher et al. The American journal of gastroenterology 2015 Nov (Posted: Nov 05, 2015 4PM)

The role of genes involved in lipolysis on weight loss program in overweight and obese individuals.
Luglio Harry Freitag et al. Journal of clinical biochemistry and nutrition 2015 Sep (2) 91-7 (Posted: Oct 06, 2015 5PM)

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Disclaimer: Articles listed in Hot Topics of the Day are selected by Public Health Genomics Branch to provide current awareness of the scientific literature and news. Inclusion in the update does not necessarily represent the views of the Centers for Disease Control and Prevention nor does it imply endorsement of the article's methods or findings. CDC and DHHS assume no responsibility for the factual accuracy of the items presented. The selection, omission, or content of items does not imply any endorsement or other position taken by CDC or DHHS. Opinion, findings and conclusions expressed by the original authors of items included in the Clips, or persons quoted therein, are strictly their own and are in no way meant to represent the opinion or views of CDC or DHHS. References to publications, news sources, and non-CDC Websites are provided solely for informational purposes and do not imply endorsement by CDC or DHHS.
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