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Hot Topics of the Day|PHGKB
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10/26/2019

Hot Topics of the Day are picked by experts to capture the latest information and publications on public health genomics and precision health for various diseases and health topics. Sources include published scientific literature, reviews, blogs and popular press articles.

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Archived Hot Topics of the Day By Date

Screening embryos for complex genetic traits called premature
J Kaiser, Science, October 25, 2019

This is the first to empirically test the viability of screening embryos” for traits that are influenced by many genes. Such tests are based on a polygenic risk score, a tool for evaluating a person's likelihood of a disease or trait that has emerged over the past decade. The ethical debate over this brave new expansion of embryo screening is just beginning.

Trends and Focus of Machine Learning Applications for Health Research
BB Jones et al, JAMA Network Open, October 25, 2019

This analysis suggests that the interdisciplinary field of machine learning for health may be accelerated by easy-to-access, well-annotated data and would benefit from greater clinician involvement to develop into translational applications.

Machine Learning Approaches to Predict 6-Month Mortality Among Patients With Cancer
RB Parikh et al, JAMA Network Open, October 25, 2019

Can machine learning algorithms identify oncology patients at risk of short-term mortality to inform timely conversations between patients and physicians regrading serious illness? This cohort study of 26?525 patients seen in oncology practices within a large academic health system investigates

Analysis Shows Women with High Breast Cancer Recurrence Scores Benefit from Chemo
NCI, October 25, 2019 Brand

For women with the most common type of early-stage breast cancer and high scores on the Oncotype DX test, receiving chemotherapy with hormone therapy after surgery can lead to excellent long-term outcomes. That’s the conclusion of a new data analysis from the NCI-funded TAILORx clinical trial.


Disclaimer: Articles listed in Hot Topics of the Day are selected by Public Health Genomics Branch to provide current awareness of the scientific literature and news. Inclusion in the update does not necessarily represent the views of the Centers for Disease Control and Prevention nor does it imply endorsement of the article's methods or findings. CDC and DHHS assume no responsibility for the factual accuracy of the items presented. The selection, omission, or content of items does not imply any endorsement or other position taken by CDC or DHHS. Opinion, findings and conclusions expressed by the original authors of items included in the Clips, or persons quoted therein, are strictly their own and are in no way meant to represent the opinion or views of CDC or DHHS. References to publications, news sources, and non-CDC Websites are provided solely for informational purposes and do not imply endorsement by CDC or DHHS.
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