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Hot Topics of the Day|PHGKB
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09/26/2020

Hot Topics of the Day are picked by experts to capture the latest information and publications on public health genomics and precision health for various diseases and health topics. Sources include published scientific literature, reviews, blogs and popular press articles.

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Susceptibility to SARS-CoV-2 Infection Among Children and Adolescents Compared With Adults: A Systematic Review and Meta-analysis.
Viner Russell M et al. JAMA pediatrics 2020 Sep

In this systematic review and meta-analysis including 32 studies, children and adolescents younger than 20 years had 44% lower odds of secondary infection with SARS-CoV-2 compared with adults 20 years and older; this finding was most marked in those younger than 10 to 14 years. Data were insufficient to conclude whether transmission of SARS-CoV-2 by children is lower than by adults.

Racism, Not Race, Drives Inequity Across the COVID-19 Continuum
R Khazanchi et al, JAMA Network Open, September 25, 2020

Researchers must interrogate structural racism and its sociopolitical consequences as a root cause of the racial health disparities we observe.8 Short-term and long-term interventions to ameliorate health inequity must address the synergistic interactions of clinical and structural risk conditions, including compounding spillover effects.

Risk factors for mortality among hospitalized patients with COVID
D Incerti et al, MEDRXIV, September 24, 2020

Diagnosing Chronic Obstructive Airway Disease: a diagnostic accuracy study of a smartphone delivered algorithm combining patient-reported symptoms and cough analysis for use in acute care consultations.
P Porter et al, MEDRXIV, September 25, 2020

The aim of this study was to develop a rapid, smartphone-based algorithm for the detection of COPD, in the presence or absence of acute respiratory infection, and then evaluate diagnostic accuracy on an independent validation set.


Disclaimer: Articles listed in Hot Topics of the Day are selected by Public Health Genomics Branch to provide current awareness of the scientific literature and news. Inclusion in the update does not necessarily represent the views of the Centers for Disease Control and Prevention nor does it imply endorsement of the article's methods or findings. CDC and DHHS assume no responsibility for the factual accuracy of the items presented. The selection, omission, or content of items does not imply any endorsement or other position taken by CDC or DHHS. Opinion, findings and conclusions expressed by the original authors of items included in the Clips, or persons quoted therein, are strictly their own and are in no way meant to represent the opinion or views of CDC or DHHS. References to publications, news sources, and non-CDC Websites are provided solely for informational purposes and do not imply endorsement by CDC or DHHS.
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