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Hot Topics of the Day|PHGKB
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07/04/2020

Hot Topics of the Day are picked by experts to capture the latest information and publications on public health genomics and precision health for various diseases and health topics. Sources include published scientific literature, reviews, blogs and popular press articles.

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Archived Hot Topics of the Day By Date

A CRISPR-based SARS-CoV-2 diagnostic assay that is robust against viral evolution and RNA editing
KH Ooi et al, July 3, 2020

The major genetic risk factor for severe COVID-19 is inherited from Neandertals
E Zeberg et al, BIORXIV, July 3, 2020

Decentralized Blockchain for Privacy-Preserving Large-Scale Contact Tracing
W Lv et al, ARXIV, July 2, 2020

Robust and sensitive detection of SARS-CoV-2 using PCR based methods
C Park et al, BIORXIV, July 3, 2020

Association between angiotensin-converting enzyme inhibitors and angiotensin II receptor blockers use and the risk of infection and clinical outcome of COVID-19: a comprehensive systematic review and meta-analysis.
C Qu et al, MEDRXIV< July 3, 2020

Sample pooling on triplets to speed up SARS-CoV-2 diagnosis using CDC FDA EUA RT-qPCR kit.
BF Paspuel et al, MEDRXIV, July 3, 2020

ROX Index Predicts Intubation in Patients with COVID-19 Pneumonia and Moderate to Severe Hypoxemic Respiratory Failure Receiving High Flow Nasal Therapy.
M Patel et al, MEDRXIV, July 3, 2020

What variables can better predict the number of infections and deaths worldwide by SARS-CoV-2? Variation through time
J Garcia et al, MEDRXIV, July 3, 2020

Routine laboratory blood tests predict SARS-CoV-2 infection using machine learning
H Sarina et al, July 3, 2020

A novel specific artificial intelligence-based method to identify COVID-19 cases using simple blood exams
F Soares, MEDRXIV, July 4, 2020

Optimal sample pooling: an efficient tool against SARS-CoV-2
R Sharma et al, MEDRXIV, July 4, 2020

Does asthma increase Covid-19 risk? Emerging research suggests a complicated connection
J Isselbacher, Stat News, July 2, 2020

Diagnosis of cytomegalovirus infection from clinical whole genome sequencing
N Ramchandar et al, Scientific Reports, July 3, 2020

Rapid whole genome sequencing of peripheral blood has been used to detect microbial DNA in acute infections. Cytomegalovirus is a herpesvirus capable of causing severe disease in neonates and immunocompromised patients. We identified CMV by matching reads that did not align to the human reference genome to a database of microbial genomes


Disclaimer: Articles listed in Hot Topics of the Day are selected by Public Health Genomics Branch to provide current awareness of the scientific literature and news. Inclusion in the update does not necessarily represent the views of the Centers for Disease Control and Prevention nor does it imply endorsement of the article's methods or findings. CDC and DHHS assume no responsibility for the factual accuracy of the items presented. The selection, omission, or content of items does not imply any endorsement or other position taken by CDC or DHHS. Opinion, findings and conclusions expressed by the original authors of items included in the Clips, or persons quoted therein, are strictly their own and are in no way meant to represent the opinion or views of CDC or DHHS. References to publications, news sources, and non-CDC Websites are provided solely for informational purposes and do not imply endorsement by CDC or DHHS.
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