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Hot Topics of the Day|PHGKB
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05/02/2020

Hot Topics of the Day are picked by experts to capture the latest information and publications on public health genomics and precision health for various diseases and health topics. Sources include published scientific literature, reviews, blogs and popular press articles.

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Archived Hot Topics of the Day By Date

Action-Informed Artificial Intelligence—Matching the Algorithm to the Problem
CL Lindsell et al, JAMA, May 2, 2020

Given the abundance of algorithms, it is remarkable there has yet to be a major shift toward the use of AI for health care decision-making. Designing a useful AI tool in health care should begin with asking what system change the AI tool is expected to precipitate.

Public Health Measures and the Reproduction Number of SARS-CoV-2
TV Ingelsby, JAMA, May 2, 2020

Substantial undocumented infection facilitates the rapid dissemination of novel coronavirus (SARS-CoV-2)
R Li et al, Science May 1, 2020

Because of their greater numbers, undocumented infections were the source for ~80% of the documented cases. Immediately after travel restrictions were imposed, ~65% of cases were documented. These findings help to explain the lightning-fast spread of this virus around the world.

The effect of human mobility and control measures on the COVID-19 epidemic in China
MUG Kraemer et al, Science, May 1, 2020

Mobility statistics offered a precise record of spread of SARS-CoV-2 at the start of 2020. The frequency of introductions from Wuhan were predictive of the size of the epidemic n other provinces. Once the virus had escaped Wuhan, strict local control measures such as social isolation, rather than travel restrictions, played the largest part in controlling spread.

An ACE therapy for COVID-19
CB Rodell, Science Trans Med, Mat 1, 2020

Public Health Response to the Initiation and Spread of Pandemic COVID-19 in the United States, February 24–April 21, 2020
A Schuchat et al, MMWR, May 1, 2020

Various factors contributed to accelerated spread during February–March 2020, including continued travel-associated importations, large gatherings, introductions into high-risk workplaces and densely populated areas, and cryptic transmission resulting from limited testing and asymptomatic and presymptomatic spread.

Race, Socioeconomic Deprivation, and Hospitalization for COVID-19 in English participants of a National Biobank
AP Patel, et al, MEDRXIV, May 2, 2020

Individual variation in susceptibility or exposure to SARS-CoV-2 lowers the herd immunity threshold
MGM Gomes et al, MEDRXIV, May 2, 2020

Development and validation of an automated radiomic CT signature for detecting COVID-19
J Guiot et al, MEDRXIV, May 2, 2020

Curbing the AI-induced enthusiasm in diagnosing COVID-19 on chest X-Rays: the present and the near-future
A Burlaccu et al, MEDRXIV, May 2, 2020


Disclaimer: Articles listed in Hot Topics of the Day are selected by Public Health Genomics Branch to provide current awareness of the scientific literature and news. Inclusion in the update does not necessarily represent the views of the Centers for Disease Control and Prevention nor does it imply endorsement of the article's methods or findings. CDC and DHHS assume no responsibility for the factual accuracy of the items presented. The selection, omission, or content of items does not imply any endorsement or other position taken by CDC or DHHS. Opinion, findings and conclusions expressed by the original authors of items included in the Clips, or persons quoted therein, are strictly their own and are in no way meant to represent the opinion or views of CDC or DHHS. References to publications, news sources, and non-CDC Websites are provided solely for informational purposes and do not imply endorsement by CDC or DHHS.
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