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Hot Topics of the Day|PHGKB
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04/25/2020

Hot Topics of the Day are picked by experts to capture the latest information and publications on public health genomics and precision health for various diseases and health topics. Sources include published scientific literature, reviews, blogs and popular press articles.

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Archived Hot Topics of the Day By Date

ACE2 polymorphisms and individual susceptibility to SARS-CoV-2 infection: insights from an in silico study
M Calcagnile et al, BIORXIV, April 24, 2020

A transcription regulatory network within the ACE2 locus may promote a pro-viral environment for SARS-CoV-2 by modulating expression of host factors.
T Fadason et al, BIORXIV, April 25, 2020

ACE2 Homo-dimerization, Human Genomic variants and Interaction of Host Proteins Explain High Population Specific Differences in Outcomes of COVID19
S Sharma et al, BIORXIV, April 24, 2020

Prediction of novel virus-host interactions by integrating clinical symptoms and protein sequences
WL Wei et al, BIORXIV, April 25, 2020

Rapid, sensitive, full genome sequencing of Severe Acute Respiratory Syndrome Virus Coronavirus 2 (SARS-CoV-2)
CR Paden et a, BIORXIV, April 24, 2020

Heterogeneous expression of the SARS-Coronavirus-2 receptor ACE2 in the human respiratory tract
ME Ortiz-Bezara et al, BIORXIV April 23, 2020

Preliminary support for a 'dry swab, extraction free' protocol for SARS-CoV-2 testing via RT-qPCR
S Srivatsan et al, BIORXIV, April 23, 2020

TARGETED PROTEOMICS FOR THE DETECTION OF SARS-COV-2 PROTEINS.
BIORXIV, April 23, 2020

The genomic variation landscape of globally-circulating clades of SARS-CoV-2 defines a genetic barcoding scheme
Q Guan et al, BioRXIV, April 23, 2020

UK Biobank-COVID-19 Data Release
UK Biobank, April 2020

Crucial new data on the health of 500,000 UK Biobank participants are being made available to scientists tackling the COVID-19 emergency. The pioneering UK Biobank resource, which follows the health of 500,000 volunteers in England, Scotland and Wales, is well placed to help answer a wide range of questions about the pandemic .

Why The True Fatality Rate Of COVID-19 Is Hard To Estimate
All Things Considered, NPR, April 24, 2020

Why Forecasting COVID-19 Deaths in the US is Critical
CDC, April 2020 Brand

Forecasts based on the use of statistical or mathematical models (subsequently referred to as “models”) aim to predict changes in national- and state-level cumulative reported COVID-19 deaths for the next four weeks.

Use of Mobile Health and Patient-Generated Data—Making Health Care Better by Making Health Care Different
SM Bradley, JAMA Network Open, April 2020

Although the potential for mHealth and patient-generated data to improve health is alluring, a focus on health outcomes alone may detract from other ways in which these tools might improve patient care.

Effect of Smartphone-Enabled Health Monitoring Devices vs Regular Follow-up on Blood Pressure Control Among Patients After Myocardial Infarction
RW Treskes et al, AJMA Network Open, APril 2020

The use of smart technology in the follow-up of patients with myocardial infarction did not have an effect on improved blood pressure control, but implementing such an intervention was feasible and accepted by patients


Disclaimer: Articles listed in Hot Topics of the Day are selected by Public Health Genomics Branch to provide current awareness of the scientific literature and news. Inclusion in the update does not necessarily represent the views of the Centers for Disease Control and Prevention nor does it imply endorsement of the article's methods or findings. CDC and DHHS assume no responsibility for the factual accuracy of the items presented. The selection, omission, or content of items does not imply any endorsement or other position taken by CDC or DHHS. Opinion, findings and conclusions expressed by the original authors of items included in the Clips, or persons quoted therein, are strictly their own and are in no way meant to represent the opinion or views of CDC or DHHS. References to publications, news sources, and non-CDC Websites are provided solely for informational purposes and do not imply endorsement by CDC or DHHS.
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