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Hot Topics of the Day|PHGKB
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04/20/2020

Hot Topics of the Day are picked by experts to capture the latest information and publications on public health genomics and precision health for various diseases and health topics. Sources include published scientific literature, reviews, blogs and popular press articles.

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Self-reported COVID-19 Symptoms Show Promise for Disease Forecasts
Carnegie-Mellon University, April 20, 2020

Delphi uses two main approaches to forecasts, both of which have proven effective regarding the flu. One, called Crowdcast, is a "wisdom of the crowds" approach, which bases its predictions on the aggregate judgments of human volunteers who submit weekly estimates. The other uses machine learning to recognize patterns in health care data that relate to past experience.

How the UK is cracking the coronavirus code
Genomics Education Program, April 17,2020

Early prediction of mortality risk among severe COVID-19 patients using machine learning
X Chen et al, MEDRXIV, April 19, 2020

183 severe COVID-19 patients (115 survivors and 68 nonsurvivors) from Tongji Hospital were used to develop predictive models. Baseline characteristics and laboratory tests were significantly different between survivors and nonsurvivors. 4 variables(age, high-sensitivity C-reactive protein level, lymphocyte count, and d-dimer level) were selected by all models.

Trends and prediction in daily incidence and deaths of COVID-19 in the United States: a search-interest based model
X Yuan et al, MEDRXIV, April 20, 2020

There were 555,245 new cases and 22,019 deaths of COVID-19 reported in the U.S. from March 1 to April 12, 2020. The search interest of COVID, COVID pneumonia, and COVID heart were correlated with COVDI-19 daily incidence with about 12-day delay (Pearson r=0.978, 0.978 and 0.979, respectively) and deaths with 19-day delay (Pearson r=0.963, 0.958 and 0.970).

Potential impact of family history–based screening guidelines on the detection of early‐onset colorectal cancer
S Gupta et al, Cancer, April 20, 2020

Of Colorectal cancer cases aged 40 to 49 years, 1 in 4 met family history–based early screening criteria, and nearly all cases who met these criteria could have had CRC diagnosed earlier (or possibly even prevented) if earlier screening had been implemented as per family history–based guidelines.

New study highlights importance of family history-based screening for colorectal cancer
H Zia, Stat News, April 20, 2020


Disclaimer: Articles listed in Hot Topics of the Day are selected by Public Health Genomics Branch to provide current awareness of the scientific literature and news. Inclusion in the update does not necessarily represent the views of the Centers for Disease Control and Prevention nor does it imply endorsement of the article's methods or findings. CDC and DHHS assume no responsibility for the factual accuracy of the items presented. The selection, omission, or content of items does not imply any endorsement or other position taken by CDC or DHHS. Opinion, findings and conclusions expressed by the original authors of items included in the Clips, or persons quoted therein, are strictly their own and are in no way meant to represent the opinion or views of CDC or DHHS. References to publications, news sources, and non-CDC Websites are provided solely for informational purposes and do not imply endorsement by CDC or DHHS.
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