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Hot Topics of the Day are picked by experts to capture the latest information and publications on public health genomics and precision health for various diseases and health topics. Sources include published scientific literature, reviews, blogs and popular press articles.

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18 hot topic(s) found with the query "Staphylococcus"

Deep learning model for personalized prediction of positive MRSA culture using time-series electronic health records
M Nigau et al, Nature Comm, March 7, 2024 (Posted: Mar 07, 2024 8AM)

From the abstract: "Methicillin-resistant Staphylococcus aureus (MRSA) poses significant morbidity and mortality in hospitals. Rapid, accurate risk stratification of MRSA is crucial for optimizing antibiotic therapy. Our study introduced a deep learning model, PyTorch_EHR, which leverages electronic health record (EHR) time-series data, including wide-variety patient specific data, to predict MRSA culture positivity within two weeks. 8,164 MRSA and 22,393 non-MRSA patient events. "

Global trends in the increasing prevalence of the fosfomycin resistance genenin Staphylococcus aureus
DFM Monte et al, Lancet Microbe, November 2023 (Posted: Nov 11, 2023 3PM)

From the paper: " Our results revealed that 59?065 (55·7%) of 106?005 S aureus strains harboured the fosB gene. Our comprehensive genomic analysis of the global distribution of S aureus strains carrying fosfomycin resistance genes revealed their presence in 34 countries. This prevalence extends to several continents, highlighting the widespread nature of this resistance mechanism."

Direct antimicrobial resistance prediction from clinical MALDI-TOF mass spectra using machine learning
C Weiss et al, Nature Medicine, January 10, 2022 (Posted: Jan 11, 2022 8AM)

This dataset combines more than 300,000 mass spectra with more than 750,000 antimicrobial resistance phenotypes from four medical institutions. Validation on a panel of clinically important pathogens, including Staphylococcus aureus, Escherichia coli and Klebsiella pneumoniae, resulting in areas under the receiver operating characteristic curve of 0.80, 0.74 and 0.74, respectively, demonstrated the potential of using machine learning to substantially accelerate antimicrobial resistance determination and change of clinical management.

Staph infections can kill- More prevention in healthcare & communities needed
CDC Vital Signs, March 2019 Brand (Posted: Mar 06, 2019 8AM)

Methicillin-resistant Staphylococcus aureus (MRSA)
Brand (Posted: Jul 05, 2016 2PM)

Staphylococcal Food Poisoning
Brand (Posted: Jul 05, 2016 2PM)

Familial Clustering of Staphylococcus aureus Bacteremia in First-Degree Relatives: A Danish Nationwide Cohort Study
Louise B. Oestergaard et al, Annals of Internal Medicine, July 5, 2016 (Posted: Jul 05, 2016 2PM)

Whole-Genome Sequencing for the Investigation of a Hospital Outbreak of MRSA in China
PZ Kong et al, PLOS One, March 2016 (Posted: Mar 18, 2016 0PM)

Rapid antibiotic-resistance predictions from genome sequence data for Staphylococcus aureus and Mycobacterium tuberculosis.
Bradley Phelim et al. Nature communications 2015 10063 (Posted: Jan 07, 2016 2PM)

Rapid antibiotic-resistance predictions from genome sequence data for Staphylococcus aureus and Mycobacterium tuberculosis
P Bradley et al, Nature Communications, December 21, 2015 (Posted: Dec 21, 2015 10AM)

Antibiotic Resistant and Virulence Determinants of Staphylococcus haemolyticus C10A as Revealed by Whole Genome Sequencing.
Chan Kok-Gan et al. J Genomics 2015 72-4 (Posted: Aug 11, 2015 3PM)

Contemporary genomic approaches in the diagnosis and typing of Staphylococcus aureus.
Williamson Deborah A et al. Pathology 2015 Apr (3) 270-5 (Posted: May 29, 2015 0PM)

Evolution and Single-Nucleotide Polymorphisms in Methicillin-Resistant Staphylococcus aureus Strains with Reduced Susceptibility to Vancomycin and Daptomycin, Based on Determination of the Complete Genome.
Yamaguchi Tetsuo et al. Antimicrob. Agents Chemother. 2015 Jun (6) 3585-7 (Posted: May 29, 2015 11AM)

Draft Genome Sequence of Bacillus amyloliquefaciens AP183 with Antibacterial Activity against Methicillin-Resistant Staphylococcus aureus.
Nasrin Shamima et al. Genome Announc 2015 (2) (Posted: May 29, 2015 11AM)

Single-molecule sequencing reveals the molecular basis of multidrug-resistance in ST772 methicillin-resistant Staphylococcus aureus.
Steinig Eike J et al. BMC Genomics 2015 (1) 388 (Posted: May 29, 2015 11AM)

Whole-Genome Sequencing for Outbreak Investigations of Methicillin-Resistant Staphylococcus aureus in the Neonatal Intensive Care Unit: Time for Routine Practice?
Azarian Taj et al. Infect Control Hosp Epidemiol 2015 May 8. 1-9 (Posted: May 29, 2015 11AM)

Interventions for the eradication of meticillin-resistant Staphylococcus aureus (MRSA) in people with cystic fibrosis.
Lo David K H et al. Cochrane Database Syst Rev 2015 CD009650 (Posted: May 02, 2015 3PM)

Comparative Whole Genome Sequencing of Community-Associated Methicillin-Resistant Staphylococcus aureus Sequence Type 8 from Primary Care Clinics in a Texas Community.
Lee Grace C et al. Pharmacotherapy 2015 Feb (2) 220-8 (Posted: Mar 30, 2015 5PM)


Disclaimer: Articles listed in Hot Topics of the Day are selected by Public Health Genomics Branch to provide current awareness of the scientific literature and news. Inclusion in the update does not necessarily represent the views of the Centers for Disease Control and Prevention nor does it imply endorsement of the article's methods or findings. CDC and DHHS assume no responsibility for the factual accuracy of the items presented. The selection, omission, or content of items does not imply any endorsement or other position taken by CDC or DHHS. Opinion, findings and conclusions expressed by the original authors of items included in the Clips, or persons quoted therein, are strictly their own and are in no way meant to represent the opinion or views of CDC or DHHS. References to publications, news sources, and non-CDC Websites are provided solely for informational purposes and do not imply endorsement by CDC or DHHS.
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