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Hot Topics of the Day are picked by experts to capture the latest information and publications on public health genomics and precision health for various diseases and health topics. Sources include published scientific literature, reviews, blogs and popular press articles.

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14 hot topic(s) found with the query "Sleep disorders"

Genetics of circadian rhythms and sleep in human health and disease.
Lane Jacqueline M et al. Nature reviews. Genetics 2022 8 (Posted: Aug 27, 2022 6AM)

Given the moderate heritability of circadian and sleep traits, genetics offers an opportunity that complements insights from model organism studies to advance our fundamental molecular understanding of human circadian and sleep physiology and linked chronic disease biology. Here, we review recent discoveries of the genetics of circadian and sleep physiology and disorders with a focus on those that reveal causal contributions to complex diseases.

Preventing Digital Overdiagnosis.
Capurro Daniel et al. JAMA 2022 1 (Posted: Jan 22, 2022 2PM)

The accelerated adoption of digital technologies in people’s lives is creating unique opportunities to leverage routinely collected digital data and machine learning models to diagnose diseases before they become symptomatic. Like traditional tests, digital screening will likely generate cases of overdiagnosis and thereby harm some patients. Digital screening tests (such as detecting mood or sleep disorders from smartphone use patterns) are being developed faster than the ability to assess their value. The additional risks and benefits of these digital tests are not only a function of their accuracy; and it is important that such approaches be validated prospectively.

HLBS-PopOmics: an online knowledge base to accelerate dissemination and implementation of research advances in population genomics to reduce the burden of heart, lung, blood, and sleep disorders
Mensah GA, et al, Genetics in Medicine, September 10, 2018 (Posted: Sep 10, 2018 10AM)

Notice of Intent to Publish a Funding Opportunity Announcement for Rare Disease Cohorts in Heart, Lung, Blood and Sleep Disorders
NHLBI, Apr 2018 Brand (Posted: Apr 24, 2018 11AM)

Sleep disorders and Parkinson disease; lessons from genetics.
Gan-Or Ziv et al. Sleep medicine reviews 2018 Jan (Posted: Apr 09, 2018 9AM)

Stimulating T4 Implementation Research to Optimize Integration of Proven-effective Interventions for Heart, Lung, and Blood Diseases and Sleep Disorders into Practice (STIMULATE)
NHLBI, Funding Announcement, 2018 Brand (Posted: Mar 05, 2018 2PM)

Genetics of Sleep Disorders.
Gehrman Philip R et al. The Psychiatric clinics of North America 2015 Dec (4) 667-81 (Posted: Feb 18, 2016 4PM)

The pathophysiology of insomnia.
Levenson Jessica C et al. Chest 2015 Apr (4) 1179-92 (Posted: Jul 01, 2015 2PM)

Obstructive sleep apnoea syndrome
P Levy et al. Nature Reviews Disease Primers, June 25, 2015 (Posted: Jul 01, 2015 2PM)

CDC Information: More than one-quarter of the U.S. population report occasionally not getting enough sleep, while nearly 10% experience chronic insomnia
Brand (Posted: Feb 25, 2015 0PM)

Are you getting enough sleep?
Brand (Posted: Feb 25, 2015 0PM)

Insomnia
From NHLBI health topic site Brand (Posted: Jan 01, 2014 0AM)

What Is Insomnia (in-SOM-ne-ah) is a common sleep disorder. People who have insomnia have trouble falling asleep, staying asleep, or both. As a result, they may get too little sleep or have poor-quality sleep. They may not feel refreshed when they wake up. Overview Insomnia can be acute (short-term) or chronic (ongoing). Acute insomnia is common and often is brought on by situations such as stress at work, family pressures, or a traumatic event. Acute insomnia lasts for days or weeks. Chronic insomnia lasts for a month or longer. Most cases of chronic insomnia are secondary, which means they are the symptom or side effect of some other problem. Certain medical conditions, medicines, sleep disorders, and substances can cause secondary insomnia. In contrast, primary insomnia isn't due to medical problems, medicines, or other substances. It is its own distinct disorder, and its cause isn?t well understood. Many life changes can trigger primary insomnia, including long-lasting stress and emotional upset. Insomnia can cause daytime sleepiness and a lack of energy. It also can make you feel anxious, depressed, or irritable. You may have trouble focusing on tasks, paying attention, learning, and remembering. These problems can prevent you from doing your best at work or school. Insomnia also can cause other serious problems. For example, you may feel drowsy while driving, which could lead to an accident. Outlook Treating the underlying cause of secondary insomnia may resolve or improve the sleep problem, especially if you can correct the problem soon after it starts. For example, if caffeine is causing your insomnia, stopping or limiting your intake of the substance might make the insomnia go away. Lifestyle changes, including better sleep habits, often help relieve acute insomnia. For chronic insomnia, your doctor may recommend medicines or cognitive-behavioral therapy.

Sleep Studies
From NHLBI health topic site Brand (Posted: Jan 01, 2014 0AM)

Also known as Polysomnography Sleep studies are painless, noninvasive tests that measure how well you sleep and how your body responds to sleep problems. Overview The more common sleep studies monitor and record data about your body during a full night of sleep. Other types of sleep studies include multiple sleep latency and daytime maintenance of wakefulness tests. Multiple sleep latency tests measure how quickly you fall asleep during a series of daytime naps and use sensors to record your brain activity and eye movements. A daytime maintenance of wakefulness test measures your ability to stay awake and alert. Sleep studies can help your doctor diagnose sleep-related breathing disorders such as sleep apnea, sleep-related seizure disorders, sleep-related movement disorders, and sleep disorders that cause extreme daytime tiredness such as narcolepsy. Doctors also may use sleep studies to help diagnose or rule out restless legs syndrome. Your doctor will determine whether you must have your sleep study at a sleep center or if you can do it at home with a portable diagnostic device. If your sleep study will be done at a sleep center, you will sleep in a bed at the sleep center for the duration of the study. Removable sensors will be placed on your scalp, face, eyelids, chest, limbs, and a finger. These sensors record your brain waves, heart rate, breathing effort and rate, oxygen levels, and muscle movements before, during, and after sleep. There is a small risk of irritation from the sensors, but this will go away after they are removed. Your doctor will review your sleep study test results and develop a treatment plan for any diagnosed sleep disorder. Untreated sleep disorders can raise your risk for heart failure, high blood pressure, stroke, diabetes, and depression. Sleep disorders also have been linked to an increased risk for injury and car accidents.

National Center on Sleep Disorders Research
From NHLBI health topic site Brand (Posted: Jan 01, 2014 0AM)

Located within the Division of Lung Diseases of the NHLBI, the National Center on Sleep Disorders Research (NCSDR) was established in 1993 to foster the coordination of sleep and circadian research within NIH and other Federal agencies. Insufficient sleep and under-treatment of sleep disorders is a national health concern that causes a substantial economic burden to the U.S. economy each year due to accidents and lost productivity.


Disclaimer: Articles listed in Hot Topics of the Day are selected by Public Health Genomics Branch to provide current awareness of the scientific literature and news. Inclusion in the update does not necessarily represent the views of the Centers for Disease Control and Prevention nor does it imply endorsement of the article's methods or findings. CDC and DHHS assume no responsibility for the factual accuracy of the items presented. The selection, omission, or content of items does not imply any endorsement or other position taken by CDC or DHHS. Opinion, findings and conclusions expressed by the original authors of items included in the Clips, or persons quoted therein, are strictly their own and are in no way meant to represent the opinion or views of CDC or DHHS. References to publications, news sources, and non-CDC Websites are provided solely for informational purposes and do not imply endorsement by CDC or DHHS.
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