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Hot Topics of the Day are picked by experts to capture the latest information and publications on public health genomics and precision health for various diseases and health topics. Sources include published scientific literature, reviews, blogs and popular press articles.

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34 hot topic(s) found with the query "Mosquito"

Using genomics to track malaria in the US
T Locke, MedicalXpress, December 20, 2023 (Posted: Dec 22, 2023 10AM)

From the website: "Both the parasite genome and the mosquito genome are very important because each of those represents a unique fingerprint. You can characterize the disease that's caused by that particular parasite and also track the parasites and the mosquitoes. Malaria parasites, for example, in parts of Ethiopia or India are different from each other, but those malaria parasites in India are similar to each other. If you don't know the origin of a malaria parasite, you can track it back to where it might have come from by comparing it with lots of different genomes of malaria parasites throughout the endemic world. "

Biotech firm announces results from first US trial of genetically modified mosquitoes Oxitec reports that its insects behaved as planned — but a larger trial is needed to learn whether they can reduce wild mosquito populations.
E Waltz, Nature, April 18, 2022 (Posted: Apr 19, 2022 7AM)

What If You Could Become Invisible to Mosquitoes? Using Crispr, scientists have taken the first step toward creating a mosquito that is blind to human hosts.
S Imbler, NY Times, August 2021 (Posted: Aug 22, 2021 7AM)

For the first time, scientists have used the gene-editing tool Crispr-Cas9 to render humans effectively invisible in the eyes of Aedes aegypti mosquitoes, which use dark visual cues to hunt, according to a paper. By eliminating two of that mosquito’s light-sensing receptors, the researchers knocked out its ability to visually target hosts.

Gene-drive suppression of mosquito populations in large cages as a bridge between lab and field
A Hammond et al, Nature Communication, July 28, 2021 (Posted: Jul 28, 2021 10AM)

CRISPR-based gene-drives targeting the gene doublesex in the malaria vector Anopheles gambiae effectively suppressed the reproductive capability of mosquito populations reared in small laboratory cages. To bridge the gap between laboratory and the field, this gene-drive technology must be challenged with vector ecology. Here we report the suppressive activity of the gene-drive in age-structured An. gambiae populations in indoor cages that permit feeding and reproductive behaviors.

Modified mosquitoes reduce cases of dengue fever- Insects infected with a disease-inhibiting bacterium were released in communities in Asia and South America
E Callaway, Nature, November 27, 2019 (Posted: Nov 29, 2019 9AM)

The findings, presented on 21 November at the annual meeting of the American Society of Tropical Medicine and Hygiene in National Harbor, Maryland, come from experimental releases of mosquitoes that carry Wolbachia bacteria, which block the replication of mosquito-borne pathogens such as the dengue, chikungunya and Zika viruses.

Transgenic Aedes aegypti Mosquitoes Transfer Genes into a Natural Population.
Evans Benjamin R et al. Scientific reports 2019 Sep (1) 13047 (Posted: Sep 15, 2019 8AM)

To control the mosquito-borne diseases yellow fever, dengue, chikungunya, and Zika fevers, a strain of transgenically modified Aedes aegypti mosquitoes containing a dominant lethal gene has been developed. Approximately 450 thousand males of this strain were released each week for 27 months in Jacobina, Bahia, Brazil.

Illnesses on the rise- From mosquito, tick, and flea bites
CDC Vital Signs, May 2018 (Posted: May 02, 2018 8AM)

Whole metagenome sequencing reveals links between mosquito microbiota and insecticide resistance in malaria vectors.
Dada Nsa et al. Scientific reports 2018 Feb (1) 2084 (Posted: Feb 06, 2018 3PM)

The creation and selection of mutations resistant to a gene drive over multiple generations in the malaria mosquito.
Hammond Andrew M et al. PLoS genetics 2017 Oct (10) e1007039 (Posted: Oct 10, 2017 10AM)

Public Response to a Proposed Field Trial of Genetically Engineered Mosquitoes in the United States
C Bloss et al, JAMA, August 15, 2017 (Posted: Aug 16, 2017 8AM)

Study Finds Public Pushing Back On Genetically Modified Mosquitoes
D Wagner, WKPBS, August 15, 2017 (Posted: Aug 16, 2017 8AM)

Mosquito 101
Brand (Posted: Aug 15, 2017 0PM)

New Gene Editing Technique to Drive Out Mosquito-Borne Disease
Frontline Genetics, June 28, 2017 (Posted: Jun 28, 2017 8PM)

New tool for combating mosquito-borne disease: Insect parasite genes
Science Magazine, February 27, 2017 (Posted: Feb 27, 2017 8PM)

Controlling Mosquito Viruses with Transcriptomics
Clinical Omics, February 2017 (Posted: Feb 26, 2017 4PM)

Gates Foundation doubling efforts to use CRISPR to create mosquito-killing technology
A Regalado, Genetic Literacy Project, September 7, 2016 (Posted: Sep 08, 2016 7AM)

Zika virus
Zika virus is spread to people through mosquito bites Brand (Posted: Jan 18, 2016 2PM)

Engineering MosquitoesÂ’ Genes to Resist Malaria
N Wade, New York Times, November 23, 2015 (Posted: Nov 30, 2015 8AM)

Using AMD to track changes in dengue and chikungunya viruses
Brand (Posted: Oct 28, 2015 4PM)

Replacing Pesticides With Genetics
D Powell, New York Times, August 31, 2015 (Posted: Aug 31, 2015 4PM)

Suppression of a Field Population of Aedes aegypti in Brazil by Sustained Release of Transgenic Male Mosquitoes.
Carvalho Danilo O et al. PLoS Negl Trop Dis 2015 Jul (7) e0003864 (Posted: Jul 07, 2015 10AM)

Silencing the buzz: a new approach to population suppression of mosquitoes by feeding larvae double-stranded RNAs.
Whyard Steve et al. Parasit Vectors 2015 96 (Posted: May 19, 2015 10AM)

Awareness and support of release of genetically modified "sterile" mosquitoes, Key West, Florida, USA.
Ernst Kacey C et al. Emerging Infect. Dis. 2015 Feb (2) 320-4 (Posted: May 19, 2015 10AM)

Buzzkill: Regulatory uncertainty plagues rollout of genetically modified mosquitoes
S Chakradhar, Nature Medicine, May 7, 2015 (Posted: May 19, 2015 10AM)

Can genetically modified mosquitoes curb Dengue fever?
PBS Newshour, May 16, 2015 (Posted: May 19, 2015 10AM)

Chikungunya virus and its mosquito vectors.
Higgs Stephen et al. Vector Borne Zoonotic Dis. 2015 Apr (4) 231-40 (Posted: May 15, 2015 11AM)

Chikungunya virus and the global spread of a mosquito-borne disease.
Weaver Scott C et al. N. Engl. J. Med. 2015 Mar 26. (13) 1231-9 (Posted: May 15, 2015 10AM)

A Multipurpose, High-Throughput Single-Nucleotide Polymorphism Chip for the Dengue and Yellow Fever Mosquito, Aedes aegypti.
Evans Benjamin R et al. G3 (Bethesda) 2015 (5) 711-8 (Posted: May 15, 2015 10AM)

Genome Engineering with CRISPR-Cas9 in the Mosquito Aedes aegypti.
Kistler Kathryn E et al. Cell Rep 2015 Apr 7. (1) 51-60 (Posted: May 15, 2015 10AM)

Dengue and Chikungunya in Our Backyard: Preventing Aedes Mosquito-Borne Disease
CDC Public Health Grand Rounds, May 2015 Brand (Posted: Feb 25, 2015 0PM)

CDC Information: Prevent Mosquito Bites
Brand (Posted: Feb 25, 2015 0PM)

Chikungunya virus
Brand (Posted: Feb 25, 2015 0PM)

Malaria
Brand (Posted: Jan 11, 2014 11AM)

Malaria is a mosquito-borne disease that can cause infected people to become very sick with high fever, chills, and flu-like illness. It can also cause death. Substantial progress has been made globally to control and eliminate malaria, but it continues to be a significant public health problem with roughly 3.2 billion people worldwide at risk for the disease.

West Nile Virus
Brand (Posted: Jan 11, 2014 11AM)

West Nile virus (WNV), a mosquito-borne illness, first emerged in the Western Hemisphere in 1999 in the New York City area and has since spread across the United States. Most people infected with WNV will have no symptoms. About 1 in 5 people infected will develop a fever with other symptoms. Less than 1 percent of those infected will develop a serious, sometimes fatal, neurologic illness.


Disclaimer: Articles listed in Hot Topics of the Day are selected by Public Health Genomics Branch to provide current awareness of the scientific literature and news. Inclusion in the update does not necessarily represent the views of the Centers for Disease Control and Prevention nor does it imply endorsement of the article's methods or findings. CDC and DHHS assume no responsibility for the factual accuracy of the items presented. The selection, omission, or content of items does not imply any endorsement or other position taken by CDC or DHHS. Opinion, findings and conclusions expressed by the original authors of items included in the Clips, or persons quoted therein, are strictly their own and are in no way meant to represent the opinion or views of CDC or DHHS. References to publications, news sources, and non-CDC Websites are provided solely for informational purposes and do not imply endorsement by CDC or DHHS.
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