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Hot Topics of the Day are picked by experts to capture the latest information and publications on public health genomics and precision health for various diseases and health topics. Sources include published scientific literature, reviews, blogs and popular press articles.

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18 hot topic(s) found with the query "Meningitis"

Development and validation of an artificial intelligence model for the early classification of the aetiology of meningitis and encephalitis: a retrospective observational study
BK Choi et al, Ebiomedicine, July 2023 (Posted: Jun 26, 2023 8AM)

Early diagnosis and appropriate treatment are essential in meningitis and encephalitis management. We aimed to implement and verify an artificial intelligence (AI) model for early aetiological determination of patients with encephalitis and meningitis and identify important variables in the classification process. Between January 1, 2006, and June 30, 2021, 283 patients were enrolled in the training/test dataset. An ensemble model with extreme gradient boosting and TabNet showed the best performance among the eight AI models with various settings in the external validation dataset (n = 220); accuracy, 0.8909; precision, 0.8987; recall, 0.8909; F1 score, 0.8948; AUROC, 0.9163. The AI model outperformed all clinicians.

COVID-19 vaccines for children
JS Gerber et al, Science, November 19, 2021 (Posted: Nov 19, 2021 6AM)

Although it is true that most children experience asymptomatic or mild disease, some will get quite sick, and a small number will die. It’s why children are vaccinated against influenza, meningitis, chickenpox, and hepatitis—none of which, even before vaccines were available, killed as many as SARS-CoV-2 per year. Some parents are understandably hesitant to vaccinate their young children. However, a choice not to get a vaccine is not a risk-free choice; rather, it’s a choice to take a different and more serious risk. The biomedical community must strive to make this clear to the public. It could be one of the most important health decisions a parent will make.

Emerging Drug-Resistant Meningitis Detected in the US
BM Kuehn, JAMA, August 11, 2020 (Posted: Aug 13, 2020 10AM)

Prevalence of Immunodeficiency in Children With Invasive Pneumococcal Disease in the Pneumococcal Vaccine Era: A Systematic Review.
Butters Coen et al. JAMA pediatrics 2019 Sep (Posted: Oct 01, 2019 8AM)

In this systematic review that included 6022 unique patients with primary invasive pneumococcal disease, children older than 2 years without a known predisposing condition presenting with their first episode of Streptococcus pneumoniae meningitis or pneumonia or recurrent invasive pneumococcal disease had rates of primary immunodeficiency as high as 26%.

Clinical Metagenomic Sequencing for Diagnosis of Meningitis and Encephalitis.
Wilson Michael R et al. The New England journal of medicine 2019 Jun (24) 2327-2340 (Posted: Jun 13, 2019 0PM)

Next-Generation Sequencing Could be a Promising Diagnostic Approach for Pathogen Detection: Pathogenic Analysis of Pediatric Bacterial Meningitis by Next-Generation Sequencing Technology Directly from Cerebrospinal Fluid Specimens
L Guo et al, BioRXIV, June 6, 2018 (Posted: Jun 07, 2018 9AM)

A world without bacterial meningitis: how genomic epidemiology can inform vaccination strategy.
Rodrigues Charlene M C et al. F1000Research 2018 401 (Posted: Apr 23, 2018 3PM)

Variation of 46 Innate Immune Genes Evaluated for their Contribution in Pneumococcal Meningitis Susceptibility and Outcome
B Ferwerda et al, Ebiomedicine, July 2016 (Posted: Jul 14, 2016 7AM)

Is the Emergence of the N. meningitidis Serogroup W ST-11 Hajj Outbreak Unraveling in the New Era of WGS?
B Toros et al. EBiomedicine, October 2015 (Posted: Oct 26, 2015 2AM)

Genetic polymorphisms associated with the inflammatory response in bacterial meningitis.
Fontes Fabrícia Lima et al. BMC medical genetics 2015 70 (Posted: Oct 23, 2015 11AM)

AMD Project: Analyzing Leading Causes of Bacterial Meningitis
Brand (Posted: Oct 22, 2015 8PM)

What is meningitis?
Brand (Posted: Oct 22, 2015 8PM)

nspA gene as a specific genetic marker for detection of Neisseria meningitidis causing bacterial meningitis.
Bhatt Neha et al. Indian J. Biochem. Biophys. 2014 Jun (3) 211-4 (Posted: Apr 21, 2015 3PM)

Bacterial meningitis
From NCATS Genetic and Rare Diseases Information Center Brand (Posted: Jan 01, 2011 0AM)

Tuberculous meningitis
From NCATS Genetic and Rare Diseases Information Center Brand (Posted: Jan 01, 2011 0AM)

Syphilitic aseptic meningitis
From NCATS Genetic and Rare Diseases Information Center Brand (Posted: Jan 01, 2011 0AM)

Neonatal meningitis
From NCATS Genetic and Rare Diseases Information Center Brand (Posted: Jan 01, 2011 0AM)

Mollaret meningitis
From NCATS Genetic and Rare Diseases Information Center Brand (Posted: Jan 01, 2011 0AM)


Disclaimer: Articles listed in Hot Topics of the Day are selected by Public Health Genomics Branch to provide current awareness of the scientific literature and news. Inclusion in the update does not necessarily represent the views of the Centers for Disease Control and Prevention nor does it imply endorsement of the article's methods or findings. CDC and DHHS assume no responsibility for the factual accuracy of the items presented. The selection, omission, or content of items does not imply any endorsement or other position taken by CDC or DHHS. Opinion, findings and conclusions expressed by the original authors of items included in the Clips, or persons quoted therein, are strictly their own and are in no way meant to represent the opinion or views of CDC or DHHS. References to publications, news sources, and non-CDC Websites are provided solely for informational purposes and do not imply endorsement by CDC or DHHS.
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