Archive
Hot Topics of the Day are picked by experts to capture the latest information and publications on public health genomics and precision health for various diseases and health topics. Sources include published scientific literature, reviews, blogs and popular press articles.
Sign up MyPHGKB to receive the daily hot topic email alert.
Archived Hot Topics of the Day By Date
RNA Injection Every 6 Months to Improve Adherence and Lower Blood Pressure in Patients With Hypertension.
Ernesto L Schiffrin et al. JAMA 2024 2
(Posted: Feb 18, 2024 7AM)
Association Between a First-Degree Family History and Self-Reported Personal History of Obesity, Diabetes, and Heart and Blood Conditions: Results From the All of Us Research Program.
Danielle Rasooly et al. J Am Heart Assoc 2023 11 e030779
(Posted: Nov 13, 2023 8PM)
Primary aldosteronism: molecular medicine meets public health.
Elena A B Azizan et al. Nat Rev Nephrol 2023 8
(Posted: Aug 25, 2023 8AM)
Cost effectiveness review of text messaging, smartphone application, and website interventions targeting T2DM or hypertension.
Ruben Willems et al. NPJ Digit Med 2023 8 (1) 150
(Posted: Aug 21, 2023 8AM)
Silencing Angiotensinogen in Hypertension.
Rhian M Touyz et al. N Engl J Med 2023 7 (3) 278-281
(Posted: Jul 20, 2023 7AM)
Zilebesiran, an RNA Interference Therapeutic Agent for Hypertension.
Akshay S Desai et al. N Engl J Med 2023 7 (3) 228-238
(Posted: Jul 20, 2023 7AM)
Cost-Effectiveness Analysis of Personalized Hypertension Prevention
ST Wang, J Per Med, June 15, 2023
(Posted: Jun 16, 2023 1PM)
Polygenic prediction of preeclampsia and gestational hypertension.
Michael C Honigberg et al. Nat Med 2023 5
(Posted: May 30, 2023 6AM)
A call to personalize anti-hypertensive treatments.
Karen O'Leary et al. Nat Med 2023 4
(Posted: May 03, 2023 6AM)
The role of aldehyde dehydrogenase 2 in cardiovascular disease.
Jian Zhang et al. Nature reviews. Cardiology 2023 2
(Posted: Feb 26, 2023 8AM)
Analysis of Pregnancy Complications and Epigenetic Gestational Age of Newborns
CL Acosta et al, JAMA Network Open, February 24, 2023
(Posted: Feb 24, 2023 11AM)
Genetic predictors of lifelong medication-use patterns in cardiometabolic diseases.
Kiiskinen Tuomo et al. Nature medicine 2023 1
(Posted: Jan 20, 2023 6AM)
Acute respiratory distress syndrome after SARS-CoV-2 infection on young adult population: International observational federated study based on electronic health records through the 4CE consortium
B Moal et al, PLOS ONE, Jan 4, 2023
(Posted: Jan 05, 2023 5AM)
Feasibility of Precision Medicine in Hypertension Management—Scope and Technological Aspects
P Nitzan et al, J Per Med, November 7, 2022
(Posted: Nov 07, 2022 9AM)
Preeclampsia, Genomics and Public Health
E Dawson et al, CDC Blog Post, October 25, 2022
(Posted: Oct 25, 2022 10AM)
Fitbit step counts clarify the association between activity and chronic disease risk
Nature Medicine, October 11, 2022
(Posted: Oct 12, 2022 8AM)
Modeling global 80-80-80 blood pressure targets and cardiovascular outcomes
SJ Pickersgill et al, Nature Medicine, July 18, 2022
(Posted: Jul 19, 2022 7AM)
Incorporating family history of disease improves polygenic risk scores in diverse populations
MLA Hujeol et al, Cell Genomics, July 13, 2022
(Posted: Jul 14, 2022 7AM)
Blood pressure measurement using only a smartphone
L Frey et al, NPJ Digital Medicine, July 6, 2022
(Posted: Jul 07, 2022 7AM)
Clinical Characterization of Copy Number Variants Associated With Neurodevelopmental Disorders in a Large-scale Multiancestry Biobank.
Birnbaum Rebecca et al. JAMA psychiatry 2022 1 (3) 250-259
(Posted: Mar 03, 2022 8AM)
Diagnostic accuracy of mercurial versus digital blood pressure measurement devices: a systematic review and meta-analysis
M Muniyandi et al, Scientific Reports, March 1, 2022
(Posted: Mar 02, 2022 7AM)
Trans-ethnic Mendelian-randomization study reveals causal relationships between cardiometabolic factors and chronic kidney disease.
Zheng Jie et al. International journal of epidemiology 2021 10
(Posted: Oct 24, 2021 6PM)
Evidence Used to Update the List of Underlying Medical Conditions Associated with Higher Risk for Severe COVID-19
CDC Science Brief, October 14, 2021
(Posted: Oct 16, 2021 8AM)
Mobile health technology for diverse populations: challenges and opportunities
JA Diao et al, NPJ Digital Medicine, September 6, 2021
(Posted: Sep 06, 2021 7AM)
Mobile health strategies for blood pressure self-management in urban populations with digital barriers: systematic review and meta-analyses
EC Khoong et al, NPJ Digital Medicine, July 22, 2021
(Posted: Jul 23, 2021 7AM)
Familial hypercholesterolemia related admission for acute coronary syndrome in the United States: Incidence, predictors, and outcomes.
Kheiri Babikir et al. Journal of clinical lipidology 2021
(Posted: Jun 04, 2021 8AM)
Central obesity, smoking habit and hypertension are associated with a blunted serological response to COVID-19 mRNA vaccine
M Watanabe et al, MERXIV, April 15, 2021
(Posted: Apr 16, 2021 7AM)
Antihypertensive treatment guided by genetics: PEARL-HT, the randomized proof-of-concept trial comparing rostafuroxin with losartan
L Citterio et al, The Pharmacogenomics Journal, March 1, 2021
(Posted: Mar 02, 2021 8AM)
Risk factors for illness severity among pregnant women with confirmed SARS-CoV-2 infection - Surveillance for Emerging Threats to Mothers and Babies Network, 20 state, local, and territorial health departments, March 29, 2020 -January 8, 2021
RR Galang et al, MEDRXIV, March 1, 2021
(Posted: Mar 02, 2021 8AM)
Non-communicable diseases pandemic and precision medicine: Is Africa ready?
T Chikowore et al, Ebiomedicine, February 2021
(Posted: Mar 01, 2021 8AM)
Polygenic Risk Scores Predict Hypertension Onset and Cardiovascular Risk.
Vaura Felix et al. Hypertension (Dallas, Tex. : 1979) 2021 HYPERTENSIONAHA12016471
(Posted: Feb 26, 2021 2PM)
American Heart Month 2021- Feeling the pressure? We can help.
CDC, February 2021
(Posted: Feb 02, 2021 11AM)
Genomics of hypertension: the road to precision medicine.
Padmanabhan Sandosh et al. Nature reviews. Cardiology 2020 Nov
(Posted: Nov 28, 2020 0PM)
Discovery of rare variants associated with blood pressure regulation through meta-analysis of 1.3 million individuals
P Surendran et al, Nature Genetics, NOvember 23, 2020
(Posted: Nov 24, 2020 8AM)
Association of Genetic West African Ancestry, Blood Pressure Response to Therapy, and Cardiovascular Risk Among Self-Reported Black Individuals in the Systolic Blood Pressure Reduction Intervention Trial (SPRINT)
S Rao et al, JAMA Cardiology, November 12, 2020
(Posted: Nov 14, 2020 10AM)
Disentangling Ancestry From Social Determinants of Health in Hypertension Disparities—An Important Step Forward
TM Powel-Wiley, JAMA Cardiology, November 13, 2020
(Posted: Nov 13, 2020 3PM)
Risk Factors for Hospitalization, Mechanical Ventilation, or Death Among 10 131 US Veterans With SARS-CoV-2 Infection
GN Ioannou et al, JAMA Network Open, September 23, 2020
(Posted: Sep 23, 2020 1PM)
Regardless of Age, Obesity and Hypertension Increase Risks With COVID-19
MH Katz, JAMA Internal Medicine, September 9, 2020
(Posted: Sep 09, 2020 3PM)
Obesity and Hypertension in the Time of COVID-19
G Rodgers et al, JAMA September 9, 2020
(Posted: Sep 09, 2020 3PM)
Factors Associated with Disease Severity and Mortality among Patients with Coronavirus Disease 2019: A Systematic Review and Meta-Analysis
V Chidambaram et al, MEDRXIV, August 13, 2020
(Posted: Aug 13, 2020 7AM)
Risk factors for mortality in patients with Coronavirus disease 2019 (COVID-19) infection: a systematic review and meta-analysis of observational studies
M Parohan et al MEDRXIV, June 4, 2020
(Posted: Jun 05, 2020 7AM)
Hypertension and Renin-Angiotensin-Aldosterone System Inhibitors in Patients with Covid-19
A Ip et al, MEDRXIV, April 29, 2020
(Posted: Apr 29, 2020 8AM)
Nearly All Patients Hospitalized With Covid-19 Had Chronic Health Issues, Study Finds- Only 6 percent of patients at one New York area health system had no chronic conditions. Hypertension, obesity and diabetes were common.
RC Rabin, NY Times, April 23, 2020
(Posted: Apr 24, 2020 8AM)
Your Risk of Getting Sick From Covid-19 May Lie in Your Genes
Bloomberg News, April 16, 2020
(Posted: Apr 19, 2020 9AM)
Accuracy of Smartphone Camera Applications for Detecting Atrial Fibrillation- A Systematic Review and Meta-analysis
JW O'SUllivan et al, JAMA Network Open, April 3, 2020
(Posted: Apr 05, 2020 8AM)
Risk factors for severe corona virus disease 2019 (COVID-19) patients : a systematic review and meta analysis
L Xu et al, MEDRXIV, April 1, 2020
(Posted: Apr 02, 2020 10AM)
Renin-Angiotensin System Blockers and the COVID-19 Pandemic: At Present There Is No Evidence to Abandon Renin-Angiotensin System Blockers.
Danser A H Jan et al. Hypertension (Dallas, Tex. : 1979) 2020 Mar HYPERTENSIONAHA12015082
(Posted: Mar 26, 2020 1PM)
COVID-19 and Angiotensin-Converting Enzyme Inhibitors and Angiotensin Receptor Blockers: What Is the Evidence?
Patel Ankit B et al. JAMA 2020 Mar
(Posted: Mar 25, 2020 9AM)
Position Statement of the ESC Council on Hypertension on ACE-Inhibitors and Angiotensin Receptor Blockers
European Society for Cardiology, March 13, 2020
(Posted: Mar 15, 2020 0PM)
Effect of Home Blood Pressure Monitoring via a Smartphone Hypertension Coaching Application or Tracking Application on Adults With Uncontrolled Hypertension- A Randomized Clinical Trial
SD Persell et al, JAMA Network Open, March 2, 2020
(Posted: Mar 03, 2020 8AM)
Molecular genetic framework underlying pulmonary arterial hypertension.
Southgate Laura et al. Nature reviews. Cardiology 2019 Aug
(Posted: Nov 06, 2019 9AM)
Precision medicine: The future of diagnostic approach to pulmonary hypertension?
Kedzierski Piotr et al. Anatolian journal of cardiology 2019 Sep (4) 168-171
(Posted: Nov 06, 2019 9AM)
Association of Daytime and Nighttime Blood Pressure With Cardiovascular Disease Events Among African American Individuals.
Yano Yuichiro et al. JAMA cardiology 2019 Aug
(Posted: Aug 26, 2019 9AM)
Gene and environmental interactions according to the components of lifestyle modifications in hypertension guidelines.
Kokubo Yoshihiro et al. Environmental health and preventive medicine 2019 Mar (1) 19
(Posted: Mar 14, 2019 9AM)
High Blood Pressure During Childhood and Adolescence
CDC, 2019
(Posted: Mar 03, 2019 10AM)
Hypertension genetic risk score is associated with burden of coronary heart disease among patients referred for coronary angiography.
Lukács Krogager Maria et al. PloS one 2018 13(12) e0208645
(Posted: Jan 02, 2019 4PM)
Can You Inherit Pulmonary Hypertension? Heres What You Should Know
Cleveland Clinic, December 10, 2018
(Posted: Dec 11, 2018 10AM)
Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits.
Evangelou Evangelos et al. Nature genetics 2018 Sep
(Posted: Sep 19, 2018 11AM)
Hypertension genomics and cardiovascular prevention.
Ng Fu Liang et al. Annals of translational medicine 2018 Aug 6(15) 291
(Posted: Sep 19, 2018 9AM)
Genetics in pulmonary arterial hypertension in a large homogeneous Japanese population.
Gamou S et al. Clinical genetics 2018 Jul (1) 70-80
(Posted: Aug 08, 2018 11AM)
Recent advances in pulmonary arterial hypertension.
Wilkins Martin R et al. F1000Research 2018
(Posted: Aug 08, 2018 11AM)
Pulmonary Hypertension Fact Sheet
CDC Information, 2018
(Posted: Aug 08, 2018 11AM)
Pharmacogenomic studies of hypertension: paving the way for personalized antihypertensive treatment.
Eadon Michael T et al. Expert review of precision medicine and drug development 2018 3(1) 33-47
(Posted: Jun 20, 2018 9AM)
The Use of Precision Medicine to Manage Obstructive Sleep Apnea Treatment in Patients with Resistant Hypertension: Current Evidence and Future Directions.
Sapiña Esther et al. Current hypertension reports 2018 Jun 20(7) 60
(Posted: Jun 11, 2018 11AM)
Genetics of Resistant Hypertension: the Missing Heritability and Opportunities.
Teixeira Samantha K et al. Current hypertension reports 2018 May 20(6) 48
(Posted: May 23, 2018 9AM)
Omics of Blood Pressure and Hypertension
DK Arnett et al, Circulation Res, May 2018
(Posted: May 12, 2018 10AM)
Genetic factors contributing to hypertension in African-based populations: A systematic review and meta-analysis.
Yako Yandiswa Y et al. Journal of clinical hypertension (Greenwich, Conn.) 2018 Mar
(Posted: Mar 11, 2018 1PM)
A systematic review of genetic mutations in pulmonary arterial hypertension.
Garcia-Rivas Gerardo et al. BMC medical genetics 2017 08 (1) 82
(Posted: Mar 07, 2018 9AM)
Pathways to pulmonary hypertension in sickle cell disease: the search for prevention and early intervention.
Shilo Natalie R et al. Expert review of hematology 2017 10 (10) 875-890
(Posted: Mar 07, 2018 9AM)
Heritable pulmonary hypertension: from bench to bedside.
Girerd Barbara et al. European respiratory review : an official journal of the European Respiratory Society 2017 Sep (145)
(Posted: Mar 07, 2018 9AM)
Precision medicine in pulmonary hypertension: Start with the end (point).
Mathai Stephen C et al. International journal of cardiology 2018 Apr 257339-340
(Posted: Mar 07, 2018 9AM)
Genetic Programming of Hypertension.
Ahn Sun-Young et al. Frontiers in pediatrics 2017 285
(Posted: Feb 13, 2018 3PM)
Genetic Predisposition to High Blood Pressure and Lifestyle Factors: Associations with Midlife Blood Pressure Levels and Cardiovascular Events.
Pazoki Raha et al. Circulation 2017 Dec
(Posted: Feb 13, 2018 3PM)
Personalized medicine-a modern approach for the diagnosis and management of hypertension.
Savoia Carmine et al. Clinical science (London, England : 1979) 2017 Nov (22) 2671-2685
(Posted: Nov 20, 2017 2PM)
Recent development of risk-prediction models for incident hypertension: An updated systematic review.
Sun Dongdong et al. PloS one 2017 (10) e0187240
(Posted: Nov 20, 2017 2PM)
Family history of high blood pressure focuses trainers mission on heart health
American Heart Association News, May 31, 2017
(Posted: Jun 03, 2017 8PM)
Heritability and risks associated with early onset hypertension: multigenerational, prospective analysis in the Framingham Heart Study
TJ Niiranen et al, BMJ, May 12, 2017
(Posted: May 15, 2017 5PM)
A Review of the Genetics of Hypertension with a Focus on Gene-Environment Interactions.
Waken R J et al. Current hypertension reports 2017 Mar (3) 23
(Posted: May 12, 2017 8AM)
The evolving science of apolipoprotein-L1 and kidney disease.
Chen Teresa K et al. Current opinion in nephrology and hypertension 2016 May (3) 217-25
(Posted: Jan 18, 2017 8AM)
Under pressure genetics of hypertension
L Koch, Nature Rev Genetics, Sept 26, 2016
(Posted: Sep 29, 2016 10PM)
Blood Pressure Control
CDC Vital Signs, September 13, 2016
(Posted: Sep 14, 2016 11AM)
Undiagnosed Hypertension
(Posted: Apr 07, 2016 0PM)
Information on Hypertension (High Blood Pressure)
About 1 of 3 U.S. adults?or about 70 million people?have high blood pressure. Only about half of these people have their high blood pressure under control
(Posted: Jan 19, 2016 2PM)
Genomics and Pharmacogenomics of Salt-sensitive Hypertension.
Armando Ines et al. Current hypertension reviews 2015 (1) 49-56
(Posted: Jan 08, 2016 9AM)
Genetics of Resistant Hypertension: a Novel Pharmacogenomics Phenotype.
El Rouby Nihal et al. Curr. Hypertens. Rep. 2015 Sep (9) 583
(Posted: Aug 24, 2015 11AM)
Pharmacogenomics of Hypertension and Heart Disease.
Arwood Meghan J et al. Curr. Hypertens. Rep. 2015 Sep (9) 586
(Posted: Aug 24, 2015 11AM)
Mechanisms of Salt-Sensitive Hypertension.
Luzardo Leonella et al. Curr Hypertens Rev 2015 (1) 14-21
(Posted: Jul 06, 2015 8AM)
Fetal programming and epigenetic mechanisms in arterial hypertension.
Scherrer Urs et al. Curr. Opin. Cardiol. 2015 Jul (4) 393-7
(Posted: Jul 06, 2015 8AM)
APOL1 genetic variants, chronic kidney diseases and hypertension in mixed ancestry South Africans.
Matsha Tandi E et al. BMC Genet. 2015 (1) 69
(Posted: Jun 30, 2015 3PM)
Mutation of SH2B3 (LNK), a Genome-Wide Association Study Candidate for Hypertension, Attenuates Dahl Salt-Sensitive Hypertension via Inflammatory Modulation.
Rudemiller Nathan P et al. Hypertension 2015 May (5) 1111-7
(Posted: May 06, 2015 0PM)
A meta-analysis of gene expression signatures of blood pressure and hypertension.
Huan Tianxiao et al. PLoS Genet. 2015 Mar (3) e1005035
(Posted: May 06, 2015 0PM)
Association of genetic variants with hypertension in a longitudinal population-based genetic epidemiological study.
Yamada Yoshiji et al. Int. J. Mol. Med. 2015 May (5) 1189-98
(Posted: May 06, 2015 0PM)
The ACE2/Apelin Signaling, MicroRNAs, and Hypertension.
Chen Lai-Jiang et al. Int J Hypertens 2015 896861
(Posted: May 06, 2015 0PM)
Genomic Research in Postmenopausal Hypertension.
Thomopoulos Costas et al. J Clin Hypertens (Greenwich) 2015 Mar 31.
(Posted: May 06, 2015 0PM)
Non-coding RNAs and Hypertension-Unveiling Unexpected Mechanisms of Hypertension by the Dark Matter of the Genome.
Murakami Kazuo et al. Curr Hypertens Rev 2015 Mar 31.
(Posted: May 06, 2015 0PM)
Association of adiponectin with type 2 diabetes and hypertension in African American men and women: the Jackson Heart Study.
Davis Sharon K et al. BMC Cardiovasc Disord 2015 (1) 13
(Posted: May 06, 2015 0PM)
Recurrent gain of function mutation in calcium channel CACNA1H causes early-onset hypertension with primary aldosteronism.
Scholl Ute I et al. Elife 2015
(Posted: May 06, 2015 0PM)
The importance of G protein-coupled receptor kinase 4 (GRK4) in pathogenesis of salt sensitivity, salt sensitive hypertension and response to antihypertensive treatment.
Rayner Brian et al. Int J Mol Sci 2015 (3) 5741-9
(Posted: May 06, 2015 0PM)
Genetic and molecular aspects of hypertension.
Padmanabhan Sandosh et al. Circ. Res. 2015 Mar 13. (6) 937-59
(Posted: May 06, 2015 0PM)
Efficacy of Folic Acid Therapy in Primary Prevention of Stroke Among Adults With Hypertension in ChinaThe CSPPT Randomized Clinical Trial
Y Huo et al. JAMA, March 12, 2015
(Posted: Mar 16, 2015 9AM)
Disclaimer: Articles listed in Hot Topics of the Day are selected by Public Health Genomics Branch to provide current awareness of the scientific literature and news. Inclusion in the update does not necessarily represent the views of the Centers for Disease Control and Prevention nor does it imply endorsement of the article's methods or findings. CDC and DHHS assume no responsibility for the factual accuracy of the items presented. The selection, omission, or content of items does not imply any endorsement or other position taken by CDC or DHHS. Opinion, findings and conclusions expressed by the original authors of items included in the Clips, or persons quoted therein, are strictly their own and are in no way meant to represent the opinion or views of CDC or DHHS. References to publications, news sources, and non-CDC Websites are provided solely for informational purposes and do not imply endorsement by CDC or DHHS.
- Page last reviewed:Feb 1, 2024
- Page last updated:Apr 25, 2024
- Content source: