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Hot Topics of the Day are picked by experts to capture the latest information and publications on public health genomics and precision health for various diseases and health topics. Sources include published scientific literature, reviews, blogs and popular press articles.

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20 hot topic(s) found with the query "Cytomegalovirus "

Comprehensive Genomic Sequencing–Based Screening for Hearing Loss in the Neonatal Intensive Care Setting—Is It Time?
AN Abou Tayoun, JAMA Network Open, July 11, 2022 (Posted: Jul 11, 2022 1PM)

A recent study suggests that targeted genetic screening—using population-specific common pathogenic variants—combined with physiological and cytomegalovirus testing may be an effective newborn screening strategy for hearing loss, in critically ill neonates and beyond. This combinatory approach has the additional benefit of identifying mild and later-onset hearing loss and providing valuable genetic information that is often missed by traditional NHBS. However, additional work is needed to characterize the genetic landscape of hearing loss across populations and to define the optimal population-wide genetic screening method for deafness.


Diagnosis of cytomegalovirus infection from clinical whole genome sequencing
N Ramchandar et al, Scientific Reports, July 3, 2020 (Posted: Jul 04, 2020 7AM)

Rapid whole genome sequencing of peripheral blood has been used to detect microbial DNA in acute infections. Cytomegalovirus is a herpesvirus capable of causing severe disease in neonates and immunocompromised patients. We identified CMV by matching reads that did not align to the human reference genome to a database of microbial genomes


Genomic and functional characteristics of human cytomegalovirus revealed by next-generation sequencing.
Sijmons Steven et al. Viruses 2014 (3) 1049-72 (Posted: Nov 27, 2015 5PM)


Manipulation of host pathways by human cytomegalovirus: insights from genome-wide studies.
Cohen Yifat et al. Seminars in immunopathology 2014 Nov (6) 651-8 (Posted: Nov 27, 2015 5PM)


Synthetic DNA approach to cytomegalovirus vaccine/immune therapy.
Wu Stephan J et al. Advances in experimental medicine and biology 2015 131-48 (Posted: Nov 27, 2015 5PM)


The Transcription and Translation Landscapes during Human Cytomegalovirus Infection Reveal Novel Host-Pathogen Interactions.
Tirosh Osnat et al. PLoS pathogens 2015 Nov (11) e1005288 (Posted: Nov 27, 2015 5PM)


High-throughput analysis of human cytomegalovirus genome diversity highlights the widespread occurrence of gene-disrupting mutations and pervasive recombination.
Sijmons Steven et al. J. Virol. 2015 May 13. (Posted: Jun 29, 2015 2PM)


A Thr72Ala polymorphism in the NKG2D gene is associated with early symptomatic congenital cytomegalovirus disease.
Taniguchi Rumi et al. Infection 2015 Jun (3) 353-9 (Posted: Jun 29, 2015 2PM)


Complete Genome Sequence of Rat Cytomegalovirus Strain ALL-03 (Malaysian Strain).
Balakrishnan Krishnan Nair et al. Genome Announc 2015 (3) (Posted: Jun 29, 2015 2PM)


What DNA viral genomic rearrangements tell us about persistence.
Imperiale Michael J et al. J. Virol. 2015 Feb (4) 1948-50 (Posted: Apr 17, 2015 2PM)


GWAS, cytomegalovirus infection, and schizophrenia.
Grove Jakob et al. Curr Behav Neurosci Rep 2014 Dec 1. (4) 215-223 (Posted: Apr 17, 2015 2PM)


Genome-wide genetic investigation of serological measures of common infections.
Rubicz Rohina et al. Eur. J. Hum. Genet. 2015 Mar 11. (Posted: Apr 17, 2015 2PM)


Human cytomegalovirus UL135 and UL136 genes are required for post-entry tropism in endothelial cells.
Bughio Farah et al. J. Virol. 2015 Apr 15. (Posted: Apr 17, 2015 2PM)


Functional annotation of human cytomegalovirus gene products: an update.
Van Damme Ellen et al. Front Microbiol 2014 218 (Posted: Apr 17, 2015 2PM)


Evaluation of DNA extraction methods for the detection of Cytomegalovirus in dried blood spots.
Koontz D et al. J. Clin. Virol. 2015 May 95-9 (Posted: Apr 17, 2015 2PM)


Decoding human cytomegalovirus.
Stern-Ginossar Noam et al. Science 2012 Nov 23. (6110) 1088-93 (Posted: Apr 17, 2015 2PM)


CDC Information: Cytomegalovirus (CMV) and Congenital CMV Infection
Brand (Posted: Feb 25, 2015 0PM)


CDC Information: Help Children with Congenital CMV Live Healthy
Brand (Posted: Feb 25, 2015 0PM)


Congenital cytomegalovirus
From NCATS Genetic and Rare Diseases Information Center Brand (Posted: Jan 01, 2011 0AM)


Cytomegalovirus retinitis
From NCATS Genetic and Rare Diseases Information Center Brand (Posted: Jan 01, 2011 0AM)



Disclaimer: Articles listed in Hot Topics of the Day are selected by Public Health Genomics Branch to provide current awareness of the scientific literature and news. Inclusion in the update does not necessarily represent the views of the Centers for Disease Control and Prevention nor does it imply endorsement of the article's methods or findings. CDC and DHHS assume no responsibility for the factual accuracy of the items presented. The selection, omission, or content of items does not imply any endorsement or other position taken by CDC or DHHS. Opinion, findings and conclusions expressed by the original authors of items included in the Clips, or persons quoted therein, are strictly their own and are in no way meant to represent the opinion or views of CDC or DHHS. References to publications, news sources, and non-CDC Websites are provided solely for informational purposes and do not imply endorsement by CDC or DHHS.
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