Archive
Hot Topics of the Day are picked by experts to capture the latest information and publications on public health genomics and precision health for various diseases and health topics. Sources include published scientific literature, reviews, blogs and popular press articles.
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Archived Hot Topics of the Day By Date
Research biobank participants attitudes towards genetic exceptionalism and health record confidentiality.
Victoria Dortenzio et al. J Community Genet 2024 3
(Posted: Apr 08, 2024 9AM)
Multi-ancestry polygenic mechanisms of type 2 diabetes
K Smith et al, Nature Medicine, March 6, 2024
(Posted: Mar 06, 2024 9AM)
Prospective study design and data analysis in UK Biobank.
Naomi E Allen et al. Sci Transl Med 2024 1 (729) eadf4428
(Posted: Jan 25, 2024 7AM)
Revolutionizing Cancer Research: The Impact of Artificial Intelligence in Digital Biobanking
C Frascarelli et al, J Per Med, September 2023
(Posted: Sep 18, 2023 11AM)
Power of Public Investment in Curated Big Health Data.
Paula Anne Newman-Casey et al. JAMA Ophthalmol 2023 9
(Posted: Sep 08, 2023 9AM)
Association of HLA diversity with the risk of 25 cancers in the UK Biobank
QL Wang et al, Ebiomedicine, May 2023
(Posted: May 05, 2023 9AM)
Participation bias in the UK Biobank distorts genetic associations and downstream analyses.
Tabea Schoeler et al. Nat Hum Behav 2023 4
(Posted: Apr 30, 2023 6AM)
Addressing Equity, Diversity, and Inclusion in the Conduct and Reporting of Genetics Research.
Kara S Bagot et al. JAMA psychiatry 2023 4
(Posted: Apr 08, 2023 0PM)
Analysis of genetic dominance in the UK Biobank.
Duncan S Palmer et al. Science (New York, N.Y.) 2023 3 (6639) 1341-1348
(Posted: Apr 06, 2023 9AM)
Public's awareness of biobanks and willingness to participate in biobanking: the moderating role of social value orientation.
Grežo Matúš et al. Journal of community genetics 2023 1
(Posted: Jan 22, 2023 8AM)
Genetic futurism.
et al. Nature genetics 2022 12 (12) 1757
(Posted: Dec 16, 2022 8AM)
Biobanking as a Tool for Genomic Research: From Allele Frequencies to Cross-Ancestry Association Studies
TE Lazavera et al, J Per Med, December 9, 2022
(Posted: Dec 10, 2022 7AM)
Multimodal biomedical AI.
Acosta Julián N et al. Nature medicine 2022 9
(Posted: Sep 20, 2022 5AM)
Celebrating 20 years of UK Biobank
UK Biobank, YouTube video, March 28, 2022
(Posted: Mar 28, 2022 9AM)
Analysis of rare genetic variation underlying cardiometabolic diseases and traits among 200,000 individuals in the UK Biobank
SJ Jurgens et al, Nature Genetics, February 17, 2022
(Posted: Feb 18, 2022 7AM)
Population-Based Penetrance of Deleterious Clinical Variants.
Forrest Iain S et al. JAMA 2022 1 (4) 350-359
(Posted: Jan 26, 2022 8AM)
Their DNA Hides a Warning, but They Don’t Want to Know What It Says
G Kolata, NY Times, January 21, 2022
(Posted: Jan 22, 2022 1PM)
The Mass General Brigham Biobank Portal: an i2b2-based data repository linking disparate and high-dimensional patient data to support multimodal analytics.
Castro Victor M et al. Journal of the American Medical Informatics Association : JAMIA 2021
(Posted: Dec 07, 2021 1PM)
Insights Into Immune-Mediated Disease and Cancer Risk-Delivering on the Promise of UK Biobank Big Data.
Stewart Douglas R et al. JAMA oncology 2021 12
(Posted: Dec 03, 2021 11AM)
Why the United States Needs a National, Coordinated Biobanking System.
Compton Carolyn et al. Annals of internal medicine 2021 11
(Posted: Nov 09, 2021 6AM)
Rare variant contribution to human disease in 281,104 UK Biobank exomes
Q Wang et al, Nature, August 10, 2021
(Posted: Aug 10, 2021 3PM)
Advancing human genetics research and drug discovery through exome sequencing of the UK Biobank.
Szustakowski Joseph D et al. Nature genetics 2021 6
(Posted: Jul 03, 2021 7AM)
Fine-scale genetic ancestry as a potential new tool for precision medicine
NP Tatonetti et al, Nature Medicine, June 18, 2021
(Posted: Jun 18, 2021 6AM)
From Genes to Public Health: Building the Evidence Base for DNA-based Population Screening
MJ Khoury et al, CDC Blog, April 9, 2021
(Posted: Apr 10, 2021 7AM)
Preferences of biobank participants for receiving actionable genomic test results: results of a recontacting study.
Henrikson Nora B et al. Genetics in medicine : official journal of the American College of Medical Genetics 2021 Feb
(Posted: Feb 20, 2021 0PM)
ESHG warns against misuses of genetic tests and biobanks for discrimination purposes.
Forzano Francesca et al. European journal of human genetics : EJHG 2021 Jan
(Posted: Jan 19, 2021 8AM)
The intersection of genomics and big data with public health: Opportunities for precision public health.
Khoury Muin J et al. PLoS medicine 2020 Oct 17(10) e1003373
(Posted: Oct 30, 2020 10AM)
Host genetics may provide some answers to COVID-19, but only with the right questions
P Duggal et al, Medium blog, May 26, 2020
(Posted: May 27, 2020 7AM)
BBMRI-ERIC’s contributions to research and knowledge exchange on COVID-19
P Holub et al, Eur J Hum Genetics, May 22, 2020
(Posted: May 22, 2020 0PM)
Future-proofing biobanks’ governance
F Gille et al, Eur J Hum Genetics, May 18, 2020
(Posted: May 19, 2020 7AM)
Researchers Suggest Genetics Might Be Behind Patient Response to COVID-19
M Terry, Biospace, April 8, 2020
(Posted: Apr 09, 2020 7AM)
Electronic health records and polygenic risk scores for predicting disease risk
R Li et al, Nat Rev Genetics, March 31, 2020
(Posted: Apr 06, 2020 8AM)
Contributions of the UK biobank high impact papers in the era of precision medicine.
Glynn Peter et al. European journal of epidemiology 2020 Jan
(Posted: Feb 02, 2020 9AM)
Return of genetic and genomic research findings: experience of a pediatric biorepository.
Papaz Tanya et al. BMC medical genomics 2019 Nov (1) 173
(Posted: Dec 02, 2019 8AM)
Data in question: A survey of European biobank professionals on ethical, legal and societal challenges of biobank research
M Goisauf et al, PLOS ONE, September 2019
(Posted: Oct 02, 2019 8AM)
Powering discovery in blood disorders and depression
A Cranage, Sanger Institute, September 2019
(Posted: Sep 16, 2019 8AM)
The generosity of 500,000 healthy volunteers could help us all
S Marshall, Wellcome Trust, September 11, 2019
(Posted: Sep 12, 2019 7AM)
UK Biobank Requires Earth's Geneticists To Cooperate, Not Compete
R Harris, NPR, August 31, 2019
(Posted: Sep 03, 2019 8AM)
Biobanking Is Changing The World
J Pandya, Forbes, August 12, 2019
(Posted: Aug 14, 2019 8AM)
The advantages of UK Biobank's open access strategy for health research
Conroy, M. et. al. JIM Journal of Internal Medicine, Jul 8, 2019
(Posted: Jul 15, 2019 9AM)
Blood samples reveal valuable data and life-changing surprises for donors
PD McCluskey, Boston Globe, July 5, 2019
(Posted: Jul 09, 2019 10AM)
Genomics of disease risk in globally diverse populations
G Gurdasani et al, Nature Rev Genetics, June 24, 2019
(Posted: Jun 24, 2019 9AM)
New genetic data on 50,000 UK Biobank participants made available to the global health research community
UK Biobank, March 10, 2019
(Posted: Mar 11, 2019 9AM)
UK Biobank Published papers
UK Biobank, 2019
(Posted: Jan 24, 2019 8AM)
Huge trove of British biodata is unlocking secrets of depression, sexual orientation, and more
J Kaiser et al, Science, January 3, 2019
(Posted: Jan 04, 2019 9AM)
Biology in the bank
J Kaiser et al, Science, January 3, 2019
(Posted: Jan 04, 2019 9AM)
UK Biobank debuts as a powerful resource for genomic research
T Manolio, Nature News, December 3, 2018
(Posted: Dec 05, 2018 8PM)
Impact of biobanks on research outcomes in rare diseases: a systematic review.
Garcia Monique et al. Orphanet journal of rare diseases 2018 Nov 13(1) 202
(Posted: Nov 14, 2018 11AM)
UK Biobank a new era in genomic medicine
OG Bahcall, Nat Rev Genetics, October 23, 2018
(Posted: Oct 24, 2018 8AM)
The UK Biobank resource with deep phenotyping and genomic data.
Bycroft Clare et al. Nature 2018 Oct (7726) 203-209
(Posted: Oct 15, 2018 10AM)
UK Biobank shares the promise of big data
N Cox, Nature News, October 10, 2018
(Posted: Oct 15, 2018 10AM)
How 500,000 Britons are critical to assessing global disease risk
UK Biobank volunteers help develop genetic tests for common disorders worldwide
C Elwell, August 22, 2018
(Posted: Aug 27, 2018 2PM)
Global Biobank Engine: enabling genotype-phenotype browsing for biobank summary statistics
G McInnes et al, BioRXIV, Apr 22, 2018
(Posted: Apr 22, 2018 0PM)
The next generation of precision medicine: observational studies, electronic health records, biobanks, and continuous monitoring.
Glicksberg Benjamin S et al. Human molecular genetics 2018 Apr
(Posted: Apr 18, 2018 10AM)
Whole genome sequencing will transform the research landscape for a wide range of diseases
US Biobank, Apr 5, 2018
(Posted: Apr 06, 2018 7AM)
Genome Database of the Latvian Population (LGDB): Design, Goals, and Primary Results.
Rovite Vita et al. Journal of epidemiology 2018 Mar
(Posted: Mar 27, 2018 1PM)
Estonia offers 100,000 citizens free genetic testing
Insights, HIMSS Europe, Mar 20, 2018
(Posted: Mar 23, 2018 1PM)
The Struggle to Build a Massive Biobank of Patient Data
G Kolata, Mar 19, 2018
(Posted: Mar 19, 2018 8AM)
Finnish researchers to create DNA database of 500,000 people for disease studies
Yle news, January 17, 2018
(Posted: Jan 17, 2018 7PM)
Perceptions of legislation relating to the sharing of genomic biobank results with donors-a survey of BBMRI-ERIC biobanks.
Brunfeldt Minna et al. European journal of human genetics : EJHG 2018 Jan
(Posted: Jan 17, 2018 11AM)
Regeneron Forms Consortium of Leading Life Sciences Companies to Accelerate Largest Widely-Available 'Big Data' Human Sequencing Resource with UK Biobank
Regeneron, Jan 9, 2018
(Posted: Jan 09, 2018 7AM)
500,000 Britons Genomes Will Be Public by 2020, Transforming Drug Research
A Regalado, Tech Review, Jan 9, 2018
(Posted: Jan 09, 2018 7AM)
Genetics and biobanks converge to resolve a vexing knowledge gap in diabetes
JC Florez, Lancet, Nov 30, 2017
(Posted: Dec 01, 2017 9AM)
What Happens When You Put 500,000 People's DNA Online
S Zhang, The Atlantic, Nov 6, 2017
(Posted: Nov 06, 2017 2PM)
High participation rate among 25 721 patients with broad age range in a hospital-based research project involving whole-genome sequencing - the Lausanne Institutional Biobank.
Bochud Murielle et al. Swiss medical weekly 2017 Oct 147w14528
(Posted: Oct 25, 2017 8AM)
Reaching for the next branch on the biobank tree of knowledge
NJ Cox, Nature Genetics, August 30, 2017
(Posted: Aug 31, 2017 0PM)
Participants' Understanding of Informed Consent for Biobanking: A Systematic Review.
Eisenhauer Elizabeth R et al. Clinical nursing research 2017 Jul 1054773817722690
(Posted: Aug 02, 2017 8AM)
Genetic data from half a million released for research
Medical research Council, UK, July 28, 2017
(Posted: Aug 01, 2017 10AM)
Genes, cells, and biobanks: Yes, theres still a consent problem
T Caulfield et al, PLOS Biology, July 25, 2017
(Posted: Jul 27, 2017 8AM)
Genome-wide genetic data on ~500,000 UK Biobank participants
C Bycroft et al. BioRxiV, July 20, 2017
(Posted: Jul 24, 2017 2PM)
Has the biobank bubble burst? Withstanding the challenges for sustainable biobanking in the digital era.
Chalmers Don et al. BMC medical ethics 2016 Jul (1) 39
(Posted: Jun 30, 2017 1PM)
Balancing the Local and the Universal in Maintaining Ethical Access to a Genomics Biobank
C Heeney et al, BioRXiv, June 2017
(Posted: Jun 30, 2017 1PM)
Engaging a state: Facebook comments on a large population biobank.
Platt Tevah et al. Journal of community genetics 2017 Apr
(Posted: Apr 12, 2017 8AM)
Public Attitudes toward Consent and Data Sharing in Biobank Research: A Large Multi-site Experimental Survey in the US.
Sanderson Saskia C et al. American journal of human genetics 2017 Mar 100(3) 414-427
(Posted: Apr 12, 2017 8AM)
Community recommendations on biobank governance: Results from a deliberative community engagement in California.
Dry Sarah M et al. PloS one 2017 12(2) e0172582
(Posted: Apr 12, 2017 8AM)
Genetic Testing and Molecular Biomarkers
Genetic Testing & Biomarkers, March 2017
(Posted: Apr 03, 2017 2PM)
Regulation of genomic and biobanking research in Africa: a content analysis of ethics guidelines, policies and procedures from 22 African countries.
de Vries Jantina et al. BMC medical ethics 2017 Feb 18(1) 8
(Posted: Feb 08, 2017 9AM)
Whose Biobank? Should Biobanks Serve Research Interests or the Needs for Personalized Medicine? Analysis of the Hungarian Law.
Sándor Judit et al. Genetic testing and molecular biomarkers 2017 Jan
(Posted: Jan 25, 2017 10AM)
Biobank attributes associated with higher patient participation: a randomized study.
Gayet-Ageron Angèle et al. European journal of human genetics : EJHG 2016 Oct
(Posted: Oct 16, 2016 8AM)
"It's all about trust": reflections of researchers on the complexity and controversy surrounding biobanking in South Africa.
Moodley Keymanthri et al. BMC medical ethics 2016 Oct (1) 57
(Posted: Oct 16, 2016 8AM)
Implementation of a Multicenter Biobanking Collaboration for Next-Generation Sequencing-Based Biomarker Discovery Based on Fresh Frozen Pretreatment Tumor Tissue Biopsies.
Bins Sander et al. The oncologist 2016 Sep
(Posted: Sep 27, 2016 11AM)
Ethics Reporting in Biospecimen and Genetic Research: Current Practice and Suggestions for Changes.
Chin William Wei Lim et al. PLoS biology 2016 Aug 14(8) e1002521
(Posted: Aug 10, 2016 9AM)
The Sangre Por Salud Biobank: Facilitating Genetic Research in an Underrepresented Latino Community.
Shaibi Gabriel et al. Public health genomics 2016 Jul
(Posted: Jul 27, 2016 10AM)
Understanding public reactions to commercialization of biobanks and use of biobank resources.
Nicol Dianne et al. Social science & medicine (1982) 2016 Jun 16279-87
(Posted: Jun 29, 2016 1PM)
Implementation of Electronic Consent at a Biobank: An Opportunity for Precision Medicine Research.
Boutin Natalie T et al. Journal of personalized medicine 2016 6(2)
(Posted: Jun 15, 2016 10AM)
Broad Consent for Genomic Research and Biobanking: Perspectives from Low- and Middle-Income Countries.
Tindana Paulina et al. Annual review of genomics and human genetics 2016 Feb
(Posted: Mar 02, 2016 9AM)
Building the Partners HealthCare Biobank at Partners Personalized Medicine: Informed Consent, Return of Research Results, Recruitment Lessons and Operational Considerations.
Karlson Elizabeth W et al. Journal of personalized medicine 6(1)
(Posted: Jan 20, 2016 11AM)
Identifying public expectations of genetic biobanks.
Critchley Christine et al. Public understanding of science (Bristol, England) 2016 Jan
(Posted: Jan 20, 2016 11AM)
Biobanks, Data Sharing, and the Drive for a Global Privacy Governance Framework.
Dove Edward S et al. The Journal of law, medicine & ethics : a journal of the American Society of Law, Medicine & Ethics 2015 Dec (4) 675-89
(Posted: Jan 06, 2016 7PM)
International Guidelines for Privacy in Genomic Biobanking (or the Unexpected Virtue of Pluralism).
Thorogood Adrian et al. The Journal of law, medicine & ethics : a journal of the American Society of Law, Medicine & Ethics 2015 Dec (4) 690-702
(Posted: Jan 06, 2016 9AM)
Genomic Databases and Biobanks in Israel.
Siegal Gil et al. The Journal of law, medicine & ethics : a journal of the American Society of Law, Medicine & Ethics 2015 Dec (4) 766-75
(Posted: Jan 06, 2016 9AM)
Regulation of Biobanks in France.
Rial-Sebbag Emmanuelle et al. The Journal of law, medicine & ethics : a journal of the American Society of Law, Medicine & Ethics 2015 Dec (4) 754-65
(Posted: Jan 06, 2016 9AM)
Spanish Regulation of Biobanks.
Nicolás Pilar et al. The Journal of law, medicine & ethics : a journal of the American Society of Law, Medicine & Ethics 2015 Dec (4) 801-15
(Posted: Jan 06, 2016 9AM)
Genomic Databases and Biobanks in Denmark.
Hartlev Mette et al. The Journal of law, medicine & ethics : a journal of the American Society of Law, Medicine & Ethics 2015 Dec (4) 743-53
(Posted: Jan 06, 2016 9AM)
Biobanking and Privacy Law in Brazil.
Dallari Sueli Gandolfi et al. The Journal of law, medicine & ethics : a journal of the American Society of Law, Medicine & Ethics 2015 Dec (4) 714-25
(Posted: Jan 06, 2016 9AM)
Biobanking and Privacy Laws in Australia.
Chalmers Don et al. The Journal of law, medicine & ethics : a journal of the American Society of Law, Medicine & Ethics 2015 Dec (4) 703-13
(Posted: Jan 06, 2016 9AM)
Returning a Research Participant's Genomic Results to Relatives: Perspectives from Managers of Two Distinct Research Biobanks
GM Petersen et al. J Law, Medicine and Ethics, Fall 2015
(Posted: Oct 21, 2015 7PM)
Million Veteran Program (MVP): A Mega-Biobank to Study Genetic Influences On Health and Disease.
Gaziano John Michael et al. Journal of clinical epidemiology 2015 Oct
(Posted: Oct 14, 2015 11AM)
Estonia Wants to Collect the DNA of All Its Citizens
the Atlantic, October 2015
(Posted: Oct 12, 2015 8AM)
Biobanks and the future of genome research
Genome Magazine, September 30, 2015
(Posted: Oct 05, 2015 9AM)
Disclaimer: Articles listed in Hot Topics of the Day are selected by Public Health Genomics Branch to provide current awareness of the scientific literature and news. Inclusion in the update does not necessarily represent the views of the Centers for Disease Control and Prevention nor does it imply endorsement of the article's methods or findings. CDC and DHHS assume no responsibility for the factual accuracy of the items presented. The selection, omission, or content of items does not imply any endorsement or other position taken by CDC or DHHS. Opinion, findings and conclusions expressed by the original authors of items included in the Clips, or persons quoted therein, are strictly their own and are in no way meant to represent the opinion or views of CDC or DHHS. References to publications, news sources, and non-CDC Websites are provided solely for informational purposes and do not imply endorsement by CDC or DHHS.
- Page last reviewed:Feb 1, 2024
- Page last updated:Apr 25, 2024
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