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Public Health Genomics and Precision Health Knowledge Base (v9.0)
PHGKB
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Public Health Genomics Branch
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Precision Health Database
Precision Health Database|Search|Public Health Genomics and Precision Health Knowledge Base (PHGKB)
Last data update: May 03, 2024
. (Total: 63769 Documents since 2012)
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Ethical implications of developing RNA-based therapies for cardiovascular disorders.
Mihaela Hostiuc et al. Front Bioeng Biotechnol 2024 121370403
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Twenty years of Gendicine® rAd-p53 cancer gene therapy: The first-in-class human cancer gene therapy in the era of personalized oncology.
Li Qi et al. Genes Dis 2024 11(4) 101155
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Adverse Events After XBB.1.5-Containing COVID-19 mRNA Vaccines.
Niklas Worm Andersson et al. JAMA 2024
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Effectiveness of Bivalent mRNA COVID-19 Vaccines in Preventing SARS-CoV-2 Infection in Children and Adolescents Aged 5 to 17 Years
LR Feldstein et al, JAMA, February 6, 2024
Vaccines reduce the risk of long COVID in children
S Hall, Nature, December 20, 2023
Self-copying RNA vaccine wins first full approval: what’s next?
E Dolgin, Nature News, December 6, 2023
mRNA COVID vaccines saved lives and won a Nobel - what's next for the technology?
Elie Dolgin et al. Nature 2023
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New COVID jabs are coming — who should get them? Countries rolling out updated vaccines weigh up whether to restrict them to high-risk individuals.
M Koslov, Nature, June 29, 2023
Risk of myocarditis and pericarditis in mRNA COVID-19-vaccinated and unvaccinated populations: a systematic review and meta-analysis.
Abdallah Alami et al. BMJ Open 2023 13(6) e065687
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Precision medicine meets cancer vaccines.
et al. Nat Med 2023
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Waning cellular immune responses and predictive factors in maintaining cellular immunity against SARS-CoV-2 six months after BNT162b2 mRNA vaccination.
Takashi Ishii et al. Sci Rep 2023 13(1) 9607
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HostSeq: a Canadian whole genome sequencing and clinical data resource.
S Yoo et al. BMC Genom Data 2023 24(1) 26
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'Remarkable' AI tool designs mRNA vaccines that are more potent and stable.
Elie Dolgin et al. Nature 2023
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Algorithm for Optimized mRNA Design Improves Stability and Immunogenicity.
He Zhang et al. Nature 2023
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A global genomic perspective on the multidrug-resistant Streptococcus pneumoniae 15A-CC63 sub-lineage following pneumococcal conjugate vaccine introduction.
Paulina A Hawkins et al. Microb Genom 9(4)
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CDC simplifies COVID-19 vaccine recommendations, allows older adults and immunocompromised adults to get second dose of the updated vaccine
CDC, April 19, 2023
Effectiveness of BNT162b2 after extending the primary series dosing interval in children and adolescents aged 5-17.
Francisco Tsz Tsun Lai et al. Nature communications 2023 14(1) 1845
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SARS-CoV-2 Omicron boosting induces de novo B cell response in humans.
Wafaa B Alsoussi et al. Nature 2023
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Conquering Alzheimer's: a look at the therapies of the future Researchers are looking to drug combinations, vaccines and gene therapy as they forge the next generation of treatments for the condition.
A Abbot, Nature, April 4, 2023
Comparative effectiveness of BNT162b2 versus mRNA-1273 covid-19 vaccine boosting in England: matched cohort study in OpenSAFELY-TPP.
William J Hulme et al. BMJ (Clinical research ed.) 2023 380e072808
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PMS2-associated Lynch syndrome: Past, present and future.
Katarina D Andini et al. Frontiers in oncology 2023 131127329
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Hydroxyurea for Children with Sickle Cell Disease in sub-Saharan Africa: A Summary of the Evidence, Opportunities, and Challenges.
Daniel Dexter et al. Pharmacotherapy 2023
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Effectiveness of mRNA COVID-19 vaccine booster doses against Omicron severe outcomes.
Ramandip Grewal et al. Nature communications 2023 14(1) 1273
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Predicting the efficacy of variant-modified COVID-19 vaccine boosters.
David S Khoury et al. Nature medicine 2023
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Financing covid-19 mRNA vaccines.
Victor Roy et al. BMJ (Clinical research ed.) 2023 380p413
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US public investment in development of mRNA covid-19 vaccines: retrospective cohort study.
Hussain S Lalani et al. BMJ (Clinical research ed.) 2023 380e073747
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Neutralization of BQ.1, BQ.1.1, and XBB with RBD-Dimer Vaccines.
Dedong Li et al. The New England journal of medicine 2023
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Elevated risk of infection with SARS-CoV-2 Beta, Gamma, and Delta variants compared with Alpha variant in vaccinated individuals.
Stijn P Andeweg et al. Science translational medicine 2022 15(684) eabn4338
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Vaccinomics: A scoping review.
Matthew Z Dudley et al. Vaccine 2023
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Effectiveness of SARS-CoV-2 Vaccines against Omicron Infection and Severe Events: A Systematic Review and Meta-Analysis of Test-Negative Design Studies
S Song et al, MEDRXIV, February 17, 2023
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Page last reviewed:
Feb 1, 2024
Page last updated:
May 03, 2024
Content source:
Public Health Genomics Branch in the Division of Blood Disorders and Public Health Genomics
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National Center on Birth Defects and Developmental Disabilities
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