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Public Health Genomics and Precision Health Knowledge Base (v9.0)
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Precision Health Database|Search|Public Health Genomics and Precision Health Knowledge Base (PHGKB)
Last data update: Apr 25, 2024
. (Total: 63675 Documents since 2012)
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Susceptibility to Treatment-Resistant Depression Within Families.
Chih-Ming Cheng et al. JAMA Psychiatry 2024
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The Finnish Adoptive Family Study of Schizophrenia: differences in somatic diseases and conditions between adoptees with high or low genetic risk for schizophrenia spectrum disorders.
Emma Karjalainen et al. Nord J Psychiatry 2024 1-7
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Clinical implementation of preemptive pharmacogenomics in psychiatry.
Maria Skokou et al. EBioMedicine 2024 101105009
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Polygenic risk scores mediating functioning outcomes through cognitive and clinical features in youth at family risk and controls.
Alex G Segura et al. Eur Neuropsychopharmacol 2024 8128-37
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Polygenic liability for antipsychotic dosage and polypharmacy - a real-world registry and biobank study.
Elise Koch et al. Neuropsychopharmacology 2024
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The relationship between familial-genetic risk and pharmacological treatment in a Swedish national sample of patients with major depression, bipolar disorder, and schizophrenia.
Kenneth S Kendler et al. Mol Psychiatry 2023
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Postpartum and non-postpartum depression: a population-based matched case-control study comparing polygenic risk scores for severe mental disorders.
Trine Munk-Olsen et al. Transl Psychiatry 2023 13(1) 346
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Multigenetic Pharmacogenomics-Guided Treatment vs Treatment As Usual Among Hospitalized Men With Schizophrenia: A Randomized Clinical Trial.
Zhewei Kang et al. JAMA Netw Open 2023 6(10) e2335518
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Schizophrenia Linked With Genetic Changes That Are Not Inherited.
Emily Harris et al. JAMA 2023
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The Nature of the Familial Risk for Psychosis in Bipolar Disorder.
Kenneth S Kendler et al. Schizophr Bull 2023
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Genome-wide analyses reveal novel opioid use disorder loci and genetic overlap with schizophrenia, bipolar disorder, and major depression.
Børge Holen et al. Addict Biol 2023 28(6) e13282
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Deep Clinical Phenotyping of Schizophrenia Spectrum Disorders Using Data-Driven Methods: Marching towards Precision Psychiatry
TD Haptewold et al, J Per Med, June 5, 2023
Musculoskeletal phenotypes in 3q29 deletion syndrome.
Rebecca M Pollak et al. medRxiv 2023
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Influences of race and clinical variables on psychiatric genetic research participation: Results from a schizophrenia sample.
Rose Mary Xavier et al. PLoS One 2023 18(4) e0284356
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The development in rating-based executive functions in children at familial high risk of schizophrenia or bipolar disorder from age 7 to age 11: the Danish high risk and resilience study.
Anna Krogh Andreassen et al. European child & adolescent psychiatry 2023
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Effect of polygenic risk score, family load of schizophrenia and exposome risk score, and their interactions, on the long-term outcome of first-episode psychosis.
M J Cuesta et al. Psychological medicine 2023 1-10
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The Progress and Pitfalls of Pharmacogenetics-Based Precision Medicine in Schizophrenia Spectrum Disorders: A Systematic Review and Meta-Analysis
Y Teng et al, J Per Med, March 4, 2023
Relationship of Family Genetic Risk Score With Diagnostic Trajectory in a Swedish National Sample of Incident Cases of Major Depression, Bipolar Disorder, Other Nonaffective Psychosis, and Schizophrenia.
Kenneth S Kendler et al. JAMA psychiatry 2023
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Study protocol of the Berlin Research Initiative for Diagnostics, Genetics and Environmental Factors in Schizophrenia (BRIDGE-S).
Braun Alice et al. BMC psychiatry 2023 23(1) 31
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New insights from the last decade of research in psychiatric genetics: discoveries, challenges and clinical implications.
Andreassen Ole A et al. World psychiatry : official journal of the World Psychiatric Association (WPA) 2023 22(1) 4-24
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Impaired motor development in children with familial high risk of schizophrenia or bipolar disorder and the association with psychotic experiences: a 4-year Danish observational follow-up study.
Burton Birgitte Klee et al. The lancet. Psychiatry 2023
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mBAT-combo: A more powerful test to detect gene-trait associations from GWAS data.
Li Ang et al. American journal of human genetics 2023 110(1) 30-43
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Associations Between Polygenic Risk Score Loading, Psychosis Liability, and Clozapine Use Among Individuals With Schizophrenia.
Lin Bochao D et al. JAMA psychiatry 2022
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DNA methylation signature aberration as potential biomarkers in treatment-resistant schizophrenia: Constructing a methylation risk score using a machine learning method.
Lu Andrew Ke-Ming et al. Journal of psychiatric research 2022 15757-65
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Association of Attention-Deficit/Hyperactivity Disorder and Depression Polygenic Scores with Lithium Response: A Consortium for Lithium Genetics Study.
Coombes Brandon J et al. Complex psychiatry 2022 7(3-4) 80-89
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Preliminary studies on apparent mendelian psychotic disorders in consanguineous families.
Kanwal Ambreen et al. BMC psychiatry 2022 22(1) 709
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Is the CYP2D6 Genotype Associated with Antipsychotic-Induced Weight Gain?
Jürgens Gesche et al. Journal of personalized medicine 2022 12(10)
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Psychiatric genetic counseling for patients with schizophrenia and their families.
Kotzé Carla et al. Frontiers in psychiatry 2022 131014069
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Mapping, clustering, and analysis of research in psychiatric genomics.
Yadav Sabita et al. Psychiatric genetics 2022
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Ribosomal DNA Abundance in the Patient’s Genome as a Feasible Marker in Differential Diagnostics of Autism and Childhood-Onset Schizophrenia
ES Ershova et al, J Per Med, October 31, 2022
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Page last reviewed:
Feb 1, 2024
Page last updated:
Apr 25, 2024
Content source:
Public Health Genomics Branch in the Division of Blood Disorders and Public Health Genomics
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National Center on Birth Defects and Developmental Disabilities
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