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Public Health Genomics and Precision Health Knowledge Base (v9.0)
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Precision Health Database|Search|Public Health Genomics and Precision Health Knowledge Base (PHGKB)
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Last data update: May 02, 2024
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Implementing a Pharmacogenomic-driven Algorithm to Guide Antiplatelet Therapy among Caribbean Hispanics: A non-randomized prospective cohort study.
Héctor Nuñez-Medina et al. medRxiv 2023
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Genetic Testing Enables the Diagnosis of Familial Hypercholesterolemia Underdiagnosed by Clinical Criteria: Analysis of Japanese Early-Onset Coronary Artery Disease Patients.
Hiroshi Miyama et al. Cardiol Res Pract 2023 20232236422
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Post-Percutaneous Coronary Intervention CYP2C19 Genotyping in an Irish population: The Potential Role in Identifying Clopidogrel Therapy Related Bleeding Risks.
Bing Wei Thaddeus Soh et al. British journal of clinical pharmacology 2023
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Prevalence of Diabetes and Its Association with Atherosclerotic Cardiovascular Disease Risk in Patients with Familial Hypercholesterolemia: An Analysis from the Hellenic Familial Hypercholesterolemia Registry (HELLAS-FH).
Boutari Chrysoula et al. Pharmaceuticals (Basel, Switzerland) 2023 16(1)
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Pharmacogenetics of P2Y Receptor Inhibitors.
Thomas Cameron D et al. Pharmacotherapy 2023
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AGTR1rs5186 Polymorphism Is Associated with the Risk of Restenosis after Percutaneous Coronary Intervention: A Meta-Analysis.
Lv Feng et al. Journal of cardiovascular development and disease 2022 9(11)
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Evaluation of race and ethnicity disparities in outcome studies of CYP2C19 genotype-guided antiplatelet therapy.
Nguyen Anh B et al. Frontiers in cardiovascular medicine 2022 9991646
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Cost-effectiveness of CYP2C19-guided P2Y12 inhibitors in Veterans undergoing percutaneous coronary intervention for acute coronary syndromes.
Dong Olivia M et al. European heart journal. Quality of care & clinical outcomes 2022
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Point of care CYP2C19 genotyping after percutaneous coronary intervention
LM Baudhuin et al, The PGX Journal, April 20, 2022
Impact of the ABCD-GENE Score on Clopidogrel Clinical Effectiveness after PCI: A Multi-site, Real-world Investigation.
Thomas Cameron D et al. Clinical pharmacology and therapeutics 2022
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CYP2C19 Genotyping in Anticoagulated Patients After Percutaneous Coronary Intervention: Should It Be Routine?
Maamari Dimitri J et al. Circulation 2022 145(10) 721-723
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Pharmacogenomic prescribing opportunities in percutaneous coronary intervention and bone marrow transplant patients.
Ratner Lindsay et al. Pharmacogenomics 2022
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Attitudes toward pharmacogenetics in patients undergoing CYP2C19 testing following percutaneous coronary intervention.
Lee Grace et al. Personalized medicine 2022
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Cost Effectiveness of a CYP2C19 Genotype-Guided Strategy in Patients with Acute Myocardial Infarction: Results from the POPular Genetics Trial.
Claassens Daniel M F et al. American journal of cardiovascular drugs : drugs, devices, and other interventions 2021
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Effects of Aging on Clinical Outcomes in Patients Receiving Genotype-Guided P2Y12 Inhibitor Selection after Percutaneous Coronary Intervention.
Wood Brian et al. Pharmacotherapy 2021
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Familial hypercholesterolemia related admission for acute coronary syndrome in the United States: Incidence, predictors, and outcomes.
Kheiri Babikir et al. Journal of clinical lipidology 2021
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Genetic testing in patients undergoing percutaneous coronary intervention: rationale, evidence and practical recommendations.
Galli Mattia et al. Expert review of clinical pharmacology 2021
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Pharmacogenetics to guide cardiovascular drug therapy.
Duarte Julio D et al. Nature reviews. Cardiology 2021
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Clopidogrel Versus Ticagrelor or Prasugrel After Primary Percutaneous Coronary Intervention According to CYP2C19 Genotype: A POPular Genetics Subanalysis.
Claassens Daniel M F et al. Circulation. Cardiovascular interventions 2021 CIRCINTERVENTIONS120009434
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Genetics, coronary artery disease, and myocardial revascularization: will novel genetic risk scores bring new answers?
Hui Sonya Kit et al. Indian journal of thoracic and cardiovascular surgery : official organ, Association of Thoracic and Cardiovascular Surgeons of India 2018 Dec 34(Suppl 3) 213-221
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Effects of the ABCB1 C3435T single nucleotide polymorphism on major adverse cardiovascular events in acute coronary syndrome or coronary artery disease patients undergoing percutaneous coronary intervention and treated with clopidogrel: A systematic review and meta-analysis.
Biswas Mohitosh et al. Expert opinion on drug safety 2020 Oct
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Impact of the CYP2C19*17 allele on outcomes in patients receiving genotype-guided antiplatelet therapy after percutaneous coronary intervention.
Lee Craig R et al. Clinical pharmacology and therapeutics 2020 Sep
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International survey of patients undergoing percutaneous coronary intervention and their attitudes toward pharmacogenetic testing.
Pereira Naveen L et al. Pharmacogenetics and genomics 2019 29(4) 76-83
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Cost-effectiveness of CYP2C19-guided antiplatelet therapy in patients with acute coronary syndrome and percutaneous coronary intervention informed by real-world data.
Limdi Nita A et al. The pharmacogenomics journal 2020 Feb
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Cost-Effectiveness of Multigene Pharmacogenetic Testing in Patients With Acute Coronary Syndrome After Percutaneous Coronary Intervention.
Dong Olivia M et al. Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research 2020 Jan 23(1) 61-73
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Prospective CYP2C19 Genotyping to Guide Antiplatelet Therapy Following Percutaneous Coronary Intervention: A Pragmatic Randomized Clinical Trial.
Tuteja Sony et al. Circulation. Genomic and precision medicine 2020 Jan
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Clinical Utility of Pharmacogene Panel-Based Testing in Patients Undergoing Percutaneous Coronary Intervention (PCI).
El Rouby Nihal et al. Clinical and translational science 2019 Nov
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Projected Cost-Effectiveness for 2 Gene-Drug Pairs Using a Multigene Panel for Patients Undergoing Percutaneous Coronary Intervention.
Hart M Ragan et al. Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research 2019 Nov 22(11) 1231-1239
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High burden of recurrent cardiovascular events in heterozygous familial hypercholesterolemia: The French Familial Hypercholesterolemia Registry.
Béliard Sophie et al. Atherosclerosis 2018 277334-340
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Clinical application of chromosome 9p21.3 genotyping in patients with coronary artery disease.
Nikulina Svetlana et al. Experimental and therapeutic medicine 2019 Oct 18(4) 3100-3108
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Page last reviewed:
Feb 1, 2024
Page last updated:
May 02, 2024
Content source:
Public Health Genomics Branch in the Division of Blood Disorders and Public Health Genomics
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National Center on Birth Defects and Developmental Disabilities
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