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Public Health Genomics and Precision Health Knowledge Base (v9.0)
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Precision Health Database|Search|Public Health Genomics and Precision Health Knowledge Base (PHGKB)
Last data update: May 02, 2024
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A Cross-Trait, Mendelian Randomization Study to Investigate Whether Migraine Is a Risk Factor for Multiple Sclerosis.
Horton Mary K et al. Neurology 2023
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Monoclonal Antibodies against Calcitonin Gene-Related Peptide for Migraine Prophylaxis: A Systematic Review of Real-World Data.
Pavelic Antun R et al. Cells 2023 12(1)
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Association of Vascular Risk Factors and Genetic Factors With Penetrance of Variants Causing Monogenic Stroke.
Cho Bernard P H et al. JAMA neurology 2022
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Chronic migraine: Genetics or environment?
Chalmer Mona Ameri et al. European journal of neurology 2021 Jan
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Common health conditions in childhood and adolescence, school absence, and educational attainment: Mendelian randomization study.
Hughes Amanda et al. NPJ science of learning 2021 Jan 6(1) 1
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Comprehensive Exonic Sequencing of Hemiplegic Migraine-Related Genes in a Cohort of Suspected Probands Identifies Known and Potential Pathogenic Variants.
Sutherland Heidi G et al. Cells 2020 Oct 9(11)
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Systematic Review of Prevalence Studies and Familial Aggregation in Vestibular Migraine.
Paz-Tamayo Ana et al. Frontiers in genetics 2020 11954
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Functional gene networks reveal distinct mechanisms segregating in migraine families.
Rasmussen Andreas H et al. Brain : a journal of neurology 2020 Sep
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Comprehensive Exonic Sequencing of Known Ataxia Genes in Episodic Ataxia.
Maksemous Neven et al. Biomedicines 2020 May 8(5)
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Migraine polygenic risk score associates with efficacy of migraine-specific drugs.
Kogelman Lisette J A et al. Neurology. Genetics 2019 Dec 5(6) e364
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The future of pharmacogenetics in the treatment of migraine.
Borro Marina et al. Pharmacogenomics 2019 Oct
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CLINGEN Actionability Report for Cerebral arteriopathy, autosomal dominant, with subcortical infarcts and leukocenphalopathy, type 1 - NOTCH3
ClinGen Actionability Working Group
CLINGEN Actionability Report for Cerebral cavernous malformations 1, 2, and 3 - KRIT1, CCM2, PDCD10
ClinGen Actionability Working Group
Genetic Risk Score for Coronary Disease Identifies Predispositions to Cardiovascular and Noncardiovascular Diseases.
Ntalla Ioanna, et al. Journal of the American College of Cardiology 2019 6 0. (23) 2932-2942
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Update on hereditary, autosomal dominant cathepsin-A-related arteriopathy with strokes and leukoencephalopathy (CARASAL).
Finsterer Josef et al. Acta neurologica Belgica 2019 Jun
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Statistical pitfalls of personalized medicine
S Senn, Nature News, November 27, 2018
Current Evidence on the Role of Epigenetic Mechanisms in Migraine: The Way Forward to Precision Medicine
P Gazerani, OBM Genetics, 2018
These Cholesterol-Reducers May Save Lives. So Why Arent Heart Patients Getting Them?
G Kolata, NY Times, October 2, 2018
Circulating Biomarkers In Migraine. New Opportunities For Precision Medicine.
Ferroni Patrizia et al. Current medicinal chemistry 2018 Jun
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Polygenic risk score: use in migraine research.
Chalmer Mona Ameri et al. The journal of headache and pain 2018 Apr 19(1) 29
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OCT1 pharmacogenetics in pain management: is a clinical application within reach?
Tzvetkov Mladen V et al. Pharmacogenomics 2017 Oct
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Genetics of Migraine: Insights into the Molecular Basis of Migraine Disorders.
Sutherland Heidi G et al. Headache 2017 Apr 57(4) 537-569
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Family studies to find rare high risk variants in migraine.
Hansen Rikke Dyhr et al. The journal of headache and pain 2017 Dec 18(1) 32
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Fragile X syndrome: an overview and update of the FMR1 gene.
Mila Montserrat et al. Clinical genetics 2017 Jun
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Classification of common human diseases derived from shared genetic and environmental determinants.
Wang Kanix, et al. Nature genetics 2017 9 0. (9) 1319-1325
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Genome-wide association studies in migraine: current state and route to follow.
Nyholt Dale R et al. Current opinion in neurology 2016 Jun 29(3) 302-8
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Migraine genetics: from genome-wide association studies to translational insights.
Gormley Padhraig, et al. Genome medicine 2016 0 0. (1) 86
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The Revolution in Migraine Genetics: From Aching Channels Disorders to a Next-Generation Medicine.
Pellacani Simona et al. Frontiers in cellular neuroscience 2016 10156
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Population-based approaches to genetics of migraine.
Chasman Daniel I et al. Cephalalgia : an international journal of headache 2016 Jun 36(7) 692-703
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Genetic predictors of human chronic pain conditions.
Zorina-Lichtenwalter Katerina et al. Neuroscience 2016 Apr
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Page last reviewed:
Feb 1, 2024
Page last updated:
May 02, 2024
Content source:
Public Health Genomics Branch in the Division of Blood Disorders and Public Health Genomics
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National Center on Birth Defects and Developmental Disabilities
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