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Public Health Genomics and Precision Health Knowledge Base (v9.0)
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Precision Health Database|Search|Public Health Genomics and Precision Health Knowledge Base (PHGKB)
Diabetes
Last data update: Apr 25, 2024
. (Total: 63675 Documents since 2012)
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Digital lifestyle treatment improves long-term metabolic control in type 2 diabetes with different effects in pathophysiological and genetic subgroups.
Vishal A Salunkhe et al. NPJ Digit Med 2023 6(1) 199
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Genotype-stratified treatment for monogenic insulin resistance: a systematic review
RK Semple et al, Comm Medicine, October 5, 2023
Insights from rare variants into the genetic architecture and biology of youth-onset type 2 diabetes.
Soo Heon Kwak et al. Res Sq 2023
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Association of triglyceride-glucose index with atherosclerotic cardiovascular disease and mortality among familial hypercholesterolemia patients.
Jun Wen et al. Diabetology & metabolic syndrome 2023 15(1) 39
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Clinical Spectrum of LMNA-Associated Type 2 Familial Partial Lipodystrophy: A Systematic Review.
Antia Fernandez-Pombo et al. Cells 2023 12(5)
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Loci for insulin processing and secretion provide insight into type 2 diabetes risk.
K Alaine Broadaway et al. American journal of human genetics 2023
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Prediction of type 2 diabetes using genome-wide polygenic risk score and metabolic profiles: A machine learning analysis of population-based 10-year prospective cohort study.
Hahn Seok-Ju et al. EBioMedicine 2022 86104383
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Integrated multiomic characterization of congenital heart disease.
Hill Matthew C et al. Nature 2022
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Association between circulating microRNAs and the metabolic syndrome in adult populations: A systematic review.
Solís-Toro Daniel et al. Diabetes & metabolic syndrome 2021 16(1) 102376
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Genetics and Clinical Characteristics of PPARγ Variant-Induced Diabetes in a Chinese Han Population.
Gong Siqian et al. Frontiers in endocrinology 2021 12677130
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Potential evidence for epigenetic biomarkers of metabolic syndrome in human whole blood in Latinos.
Urashima Keane et al. PloS one 2021 16(10) e0259449
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Genetic and clinical heterogeneity of permanent neonatal diabetes mellitus: a single tertiary centre experience.
Laimon Wafaa et al. Acta diabetologica 2021
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HDL-enriched miR-30a-5p is associated with HDL-cholesterol levels and glucose metabolism in healthy men and women.
Clément Andrée-Anne et al. Epigenomics 2021
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The comparison of the effectiveness and safety of drospirone ethinyl estradiol and ethinyl estradiol cyproterone in the treatment of polycystic ovarian syndrome: A protocol for systematic review and meta-analysis.
Liu Zhimin et al. Medicine 2020 Dec 99(51) e23811
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Significance of Homocysteine Levels in the Management of Polycystic Ovarian Syndrome: A Literature Review.
Kondapaneni Varshitha et al. Cureus 2020 Oct 12(10) e11110
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IGF2BP2 Polymorphisms Are Associated with Clinical Characteristics and Development of Oral Cancer.
Chou Chia-Hsuan et al. International journal of molecular sciences 2020 Aug 21(16)
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Dietary Recommendations for Familial Hypercholesterolaemia: an Evidence-Free Zone.
Diamond David M et al. BMJ evidence-based medicine 2020 Jul
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Evaluation of the suitability of 19 pharmacogenomics biomarkers for individualized metformin therapy for type 2 diabetes patients.
Xhakaza Lettilia et al. Drug metabolism and personalized therapy 2020 Jun
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Understanding the Pathogenesis, Therapeutic Targets/Drug Action and Pharmacogenetics of Type 2 Diabetes: Is there a Future for Personalised Medicine?
Engwa Godwill Azeh et al. Endocrine, metabolic & immune disorders drug targets 2020 Apr
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New clinical screening strategy to distinguish HNF1A variant-induced diabetes from young early-onset type 2 diabetes in a Chinese population.
Ma Yumin et al. BMJ open diabetes research & care 2020 Mar 8(1)
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Lifestyle intervention modifies the effect of the MC4R genotype on changes in insulin resistance among women with prior gestational diabetes: Tianjin Gestational Diabetes Mellitus Prevention Program.
Chen Yuhang et al. The American journal of clinical nutrition 2019 110(3) 750-758
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An unsupervised learning approach to identify novel signatures of health and disease from multimodal data.
Shomorony Ilan et al. Genome medicine 2020 Jan 12(1) 7
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Prevention of Potential Adverse Metabolic Effects of a Supplementation with Omega-3 Fatty Acids Using a Genetic Score Approach.
Franck Maximilien et al. Lifestyle genomics 2019 Nov 1-11
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Progress in pediatrics in 2015: choices in allergy, endocrinology, gastroenterology, genetics, haematology, infectious diseases, neonatology, nephrology, neurology, nutrition, oncology and pulmonology.
Caffarelli Carlo et al. Italian journal of pediatrics 2016 Aug 42(1) 75
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High Genetic Risk Scores of ASIC2, MACROD2, CHRM3, and C2orf83 Genetic Variants Associated with Polycystic Ovary Syndrome Impair Insulin Sensitivity and Interact with Energy Intake in Korean Women.
Kim Sung-Hoon et al. Gynecologic and obstetric investigation 2019 84(3) 225-236
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Genomics and PCOS
Genomics Education UK, August 5, 2019
CLINGEN Actionability Report for Hyperandrogenism, nonclassic type, due to 21-hydroxylase deficiency - CYP21A2
ClinGen Actionability Working Group
Effects of melatonin administration on mental health parameters, metabolic and genetic profiles in women with polycystic ovary syndrome: A randomized, double-blind, placebo-controlled trial.
Shabani Azade et al. Journal of affective disorders 2019 25051-56
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Supplementation with Akkermansia muciniphila in overweight and obese human volunteers: a proof-of-concept exploratory study.
Depommier Clara, et al. Nature medicine 2019 7 0. (7) 1096-1103
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Identification of type 2 diabetes loci in 433,540 East Asian individuals
CN Spracklen et al, BioRXIV, June 28, 2019
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Page last reviewed:
Feb 1, 2024
Page last updated:
Apr 25, 2024
Content source:
Public Health Genomics Branch in the Division of Blood Disorders and Public Health Genomics
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National Center on Birth Defects and Developmental Disabilities
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