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Public Health Genomics and Precision Health Knowledge Base (v9.0)
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Last data update: May 03, 2024
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Population Screening for Hereditary Hemochromatosis
Video Webinar, UNC Precision Public Health Network,
Health Economic Evaluations of Hemochromatosis Screening and Treatment: A Systematic Review.
Malvina Hoxha et al. Pharmacoecon Open 2024
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Testing and Management of Iron Overload After Genetic Screening-Identified Hemochromatosis.
Juliann M Savatt et al. JAMA Netw Open 2023 6(10) e2338995
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Haemochromatosis.
Paul C Adams et al. Lancet 2023
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Current German Guidelines on Diagnosis and Treatment of Secondary Hemochromatosis in Patients with Congenital Anemias.
Cario Holger et al. Klinische Padiatrie 2022 234(6) 368-373
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Diagnosis and Management of Hereditary Hemochromatosis.
Cabrera Elizabeth et al. JAMA 2022 328(18) 1862-1863
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C282Y/H63D Compound Heterozygosity Is a Low Penetrance Genotype for Iron Overload-related Disease.
Hasan S M Mahmudul et al. Journal of the Canadian Association of Gastroenterology 2022 5(5) 240-247
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Twenty-Five Years of Contemplating Genotype-Based Hereditary Hemochromatosis Population Screening.
Schmidtke Jörg et al. Genes 2022 13(9)
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Association of Genetic Variant Linked to Hemochromatosis With Brain Magnetic Resonance Imaging Measures of Iron and Movement Disorders.
Loughnan Robert et al. JAMA neurology 2022
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Genetic modifiers of penetrance to liver endpoints in HFE hemochromatosis: associations in a large community cohort.
Pilling Luke C et al. Hepatology (Baltimore, Md.) 2022
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Hereditary hemochromatosis and liver transplantation: a survey of symptoms, lifestyle, and physician counseling pre- and post-transplant.
Zaver Himesh B et al. Clinics and research in hepatology and gastroenterology 2022 101898
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[Increased use of genetic health care in Iceland 2012-2017].
Hognason Hakon Bjorn et al. Laeknabladid 2021 108(1) 11-16
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HFE hemochromatosis: an overview about therapeutic recommendations.
Cancado Rodolfo D et al. Hematology, transfusion and cell therapy 2021
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Hereditary Hemochromatosis: Rapid Evidence Review.
Kane Shawn F et al. American family physician 2021 104(3) 263-270
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HFE Genotype, Ferritin Levels and Transferrin Saturation in Patients with Suspected Hereditary Hemochromatosis.
Sandnes Miriam et al. Genes 2021 12(8)
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Tier 1 Guidelines on Family-Based Screening for Hereditary Hemochromatosis
D Dotson et al, CDC Blog Post, March 12, 2021
A survey of lifestyle habits, physician counseling, and direct-to consumer genetic testing in patients with hereditary hemochromatosis.
Koop Andree H et al. Clinics and research in hepatology and gastroenterology 2021 101658
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Clinical Penetrance of Hereditary Hemochromatosis-Related End-Organ Damage of C282Y Homozygosity, A Newfoundland Experience.
Lim Dennis R et al. Clinical and translational gastroenterology 2020 Nov 11(11) e00258
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Influence of VDR and HFE polymorphisms on blood lead levels of occupationally exposed workers.
Mani Monica Shirley et al. Human & experimental toxicology 2020 Nov 960327120975451
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Association of Hemochromatosis HFE p.C282Y Homozygosity With Hepatic Malignancy
JL Atkins et al, JAMA, November 24, 2020
Are We Ready for Population Screening for Hereditary Hemochromatosis?
S Grosse et al, CDC Blog, September 28, 2020
Evaluation of a screening program for iron overload and HFE mutations in 50,493 blood donors.
Eckerström Carl et al. Annals of hematology 2020 Aug
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Systematic review of the clinical outcomes of iron reduction in Hereditary Hemochromatosis.
Prabhu Anil et al. Hepatology (Baltimore, Md.) 2020 Jun
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Pediatric reporting of genomic results study (PROGRESS): a mixed-methods, longitudinal, observational cohort study protocol to explore disclosure of actionable adult- and pediatric-onset genomic variants to minors and their parents.
Savatt Juliann M et al. BMC pediatrics 2020 May 20(1) 222
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Genetic testing costs and compliance with clinical best practices.
Montanez Kathleen et al. Journal of genetic counseling 2020 May
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Failure to follow up on a medically actionable finding from direct to consumer genetic testing: A case report.
Garmany Ramin et al. Molecular genetics & genomic medicine 2020 Apr e1252
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Hemochromatosis in India: First Report of Whole Exome Sequencing With Review of the Literature.
Koshy Abraham et al. Journal of clinical and experimental hepatology 10(2) 163-169
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Diagnosis and management of hereditary haemochromatosis.
Murphree Catherine R et al. Vox sanguinis 2020 Feb
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Hereditary Hemochromatosis: Are We Ready for Population Screening?
CDC Seminar, January 15, 2019
Diagnosis and Management of Genetic Iron Overload Disorders.
Palmer William C et al. Journal of general internal medicine 2018 33(12) 2230-2236
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Page last reviewed:
Feb 1, 2024
Page last updated:
May 03, 2024
Content source:
Public Health Genomics Branch in the Division of Blood Disorders and Public Health Genomics
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National Center on Birth Defects and Developmental Disabilities
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