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Public Health Genomics and Precision Health Knowledge Base (v9.0)
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Precision Health Database|Search|Public Health Genomics and Precision Health Knowledge Base (PHGKB)
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Last data update: Apr 25, 2024
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Trial Confirms CAR T-Cell Therapy Benefits People with Aggressive Lymphomas
S Reynolds, NCI Blog, July 2023
Integrated Genomic DNA/RNA Profiling vs Fluorescence in Situ Hybridization in the Detection of MYC and BCL2 (and BCL6) Rearrangements in Large B-Cell Lymphomas: Updates Amid the New WHO Classification of Lymphoid Neoplasms.
Luiz Paulo de Lima Guido et al. American journal of clinical pathology 2023
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Mutation analysis performed on tumor biopsies from patients with newly-diagnosed germinal center aggressive B cell lymphomas.
Landsburg Daniel J et al. Oncotarget 2022 131237-1244
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Budget Impact Analysis of CAR T-cell Therapy for Adult Patients With Relapsed or Refractory Diffuse Large B-cell Lymphoma in Germany.
Skalt Daniela et al. HemaSphere 2022 6(7) e736
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Cost-Effectiveness of Molecularly Guided Treatment in Diffuse Large B-Cell Lymphoma (DLBCL) in Patients under 60.
Regier Dean A et al. Cancers 2022 14(4)
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High grade B-cell lymphoma with MYC, BCL2 and/or BCL6 rearrangements: unraveling the genetic landscape of a rare aggressive subtype of non-Hodgkin lymphoma.
Ferrari Anna et al. Leukemia & lymphoma 2022 1-7
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B-cell lymphoma 6 expression is not associated with live birth in a normal responder in vitro fertilization population.
Klimczak Amber M et al. Fertility and sterility 2021
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Primary Mediastinal B-Cell Lymphoma: A 2021 Update on Genetics, Diagnosis, and Novel Therapeutics.
Ahmed Zahoor et al. Clinical lymphoma, myeloma & leukemia 2021
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The long road to the first FDA-approved gene therapy: chimeric antigen receptor T cells targeting CD19.
Braendstrup Peter et al. Cytotherapy 2020 22(2) 57-69
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Prognostic Significance of MYC Rearrangement and Translocation Partner in Diffuse Large B-Cell Lymphoma: A Study by the Lunenburg Lymphoma Biomarker Consortium.
Rosenwald Andreas et al. Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2019 37(35) 3359-3368
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Clinical utility of target capture-based panel sequencing in hematological malignancies: a multicenter feasibility study.
Yasuda Takahiko et al. Cancer science 2020 Jul
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Comprehensive Genomic Analysis of Noonan Syndrome and Acute Myeloid Leukemia in Adults: A Review and Future Directions.
Alhumaid Muhned S et al. Acta haematologica 2020 Jun 1-11
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An integrated prognosis model of pharmacogenomic gene signature and clinical information for diffuse large B-cell lymphoma patients following CHOP-like chemotherapy.
Hu Jinglei et al. Journal of translational medicine 2020 Mar 18(1) 144
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The application of antigen receptor gene rearrangement of BIOMED-2 in the pathologic diagnosis of 348 cases with non-Hodgkin lymphoma in a single institution in Southwest of China.
Liu Xueni et al. Pathology, research and practice 2019 Nov 215(11) 152615
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Diffuse Large B-Cell Lymphoma and High-Grade B-Cell Lymphoma: Genetic Classification and Its Implications for Prognosis and Treatment.
Crombie Jennifer L et al. Surgical oncology clinics of North America 2020 Jan 29(1) 115-125
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Family Members at Higher Risk for Blood Cancers
P Harrison, Medscape, September 9, 2019
Opportunities in Cancer Research: The Immune System and Microbiome
NCI 2021 annual plan, 2019
FDA Approvals Provide Advances for a Range of Cancer Types
K Honey, AACR Blogs, August 6, 2019
Local Coverage Determination (LCD): Flow Cytometry (L33661)
The U.S. Centers for Medicare & Medicaid Services
Gene expression profiles analysis identifies a novel two-gene signature to predict overall survival in diffuse large B-cell lymphoma.
Sun Chengtao et al. Bioscience reports 2019 39(1)
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The Use of Optimal Treatment for DLBCL Is Improving in All Age Groups and Is a Key Factor in Overall Survival, but Non-Clinical Factors Influence Treatment.
Wong Doo Nicole et al. Cancers 2019 Jul 11(7)
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Dynamic Risk Profiling Using Serial Tumor Biomarkers for Personalized Outcome Prediction.
Kurtz David M, et al. Cell 2019 7 0. (3) 699-713.e19
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Clinical Significance of BCL2 , C- MYC , and BCL6 Genetic Abnormalities, Epstein-Barr Virus Infection, CD5 Protein Expression, Germinal Center B Cell/Non-Germinal Center B-Cell Subtypes, Co-expression of MYC/BCL2 Proteins and Co-expression of MYC/BCL2/BCL6 Proteins in Diffuse Large B-Cell Lymphoma: A Clinical and Pathological Correlation Study of 120 Patients.
Ting Choo-Yuen et al. International journal of medical sciences 2019 16(4) 556-566
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MYD88 mutations identify a molecular subgroup of diffuse large B-cell lymphoma with an unfavourable prognosis.
Vermaat Joost S et al. Haematologica 2019 May
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Examination of the Biomark assay as an alternative to Oncotype DX for defining chemotherapy benefit.
Kim Jinkyoung et al. Oncology letters 2019 Feb 17(2) 1812-1818
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Dose-adjusted EPOCH-R (etoposide, prednisone, vincristine, cyclophosphamide, doxorubicin, and rituximab) in untreated aggressive diffuse large B-cell lymphoma with MYC rearrangement: a prospective, multicentre, single-arm phase 2 study.
Dunleavy Kieron et al. The Lancet. Haematology 2018 Dec 5(12) e609-e617
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Genomics of aggressive B-cell lymphoma.
Rosenthal Allison et al. Hematology. American Society of Hematology. Education Program 2018 Nov 2018(1) 69-74
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Clinical Utility of In Situ Hybridization Assays in Head and Neck Neoplasms.
Luk Peter P et al. Head and neck pathology 2018 Nov
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Circulating tumor DNA: clinical roles in diffuse large B cell lymphoma.
Wu Fang-Tian et al. Annals of hematology 2018 Oct
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Dissecting aggressive B-cell lymphoma through genomic analysis - What is clinically relevant?
Scott David W et al. Best practice & research. Clinical haematology 2018 Sep 31(3) 187-198
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Page last reviewed:
Feb 1, 2024
Page last updated:
Apr 25, 2024
Content source:
Public Health Genomics Branch in the Division of Blood Disorders and Public Health Genomics
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National Center on Birth Defects and Developmental Disabilities
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