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Public Health Genomics and Precision Health Knowledge Base (v9.0)
PHGKB
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Public Health Genomics Branch
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Precision Health Database|Search|Public Health Genomics and Precision Health Knowledge Base (PHGKB)
Heart, Lung, Blood and Sleep Disorders
Last data update: Apr 25, 2024
. (Total: 63675 Documents since 2012)
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Familial risk of vasospastic angina: a nationwide family study in Sweden.
Fabrizio Ricci et al. Open Heart 2023 10(2)
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Familial hypercholesterolemia is related to cardiovascular disease, heart failure and atrial fibrillation. Results from a population-based study.
Hayato Tada et al. Eur J Clin Invest 2023 e14119
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Coronary artery calcium among patients with heterozygous familial hypercholesterolaemia.
Hayato Tada et al. Eur Heart J Open 2023 3(3) oead046
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Association of Lipoprotein (a) in Coronary Artery Disease in Young Individuals.
Patted Aishwarya et al. The Journal of the Association of Physicians of India 2022 70(4) 11-12
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Impact of the ABCD-GENE Score on Clopidogrel Clinical Effectiveness after PCI: A Multi-site, Real-world Investigation.
Thomas Cameron D et al. Clinical pharmacology and therapeutics 2022
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Pharmacogenomics of the Efficacy and Safety of Colchicine in COLCOT.
Dubé Marie-Pierre et al. Circulation. Genomic and precision medicine 2021 Feb
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Sex differences in cardiovascular morbidity associated with familial hypercholesterolaemia: A retrospective cohort study of the UK Simon Broome register linked to national hospital records.
Iyen Barbara et al. Atherosclerosis 2020 Oct
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microRNA neural networks improve diagnosis of acute coronary syndrome (ACS).
Kayvanpour Elham et al. Journal of molecular and cellular cardiology 2020 Apr
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Patients with High Genome-Wide Polygenic Risk Scores for Coronary Artery Disease May Receive Greater Clinical Benefit from Alirocumab Treatment in the Odyssey Outcomes Trial.
Damask Amy et al. Circulation 2019 Nov
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High burden of recurrent cardiovascular events in heterozygous familial hypercholesterolemia: The French Familial Hypercholesterolemia Registry.
Béliard Sophie et al. Atherosclerosis 2018 277334-340
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Genetically determined serum urate levels and cardiovascular and other diseases in UK Biobank cohort: A phenome-wide mendelian randomization study.
Li Xue et al. PLoS medicine 2019 Oct 16(10) e1002937
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Contribution of genetics to visceral adiposity and its relation to cardiovascular and metabolic disease.
Karlsson Torgny, et al. Nature medicine 2019 0 0. (9) 1390-1395
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Local Coverage Determination (LCD): CYP2C19, CYP2D6, CYP2C9, and VKORC1 Genetic Testing (L35698)
The U.S. Centers for Medicare & Medicaid Services
Local Coverage Determination (LCD): Corus CAD Test (L36713)
The U.S. Centers for Medicare & Medicaid Services
CLINGEN Actionability Report for Fabry Disease - GLA
ClinGen Actionability Working Group
CLINGEN Actionability Report for Homozygous Familial Hypercholesterolemia - LDLR, APOB, PCSK9
ClinGen Actionability Working Group
CLINGEN Actionability Report for Primary pulmonary hypertension 1- BMPR2
ClinGen Actionability Working Group
Risk of Premature Atherosclerotic Disease in Patients With Monogenic Versus Polygenic Familial Hypercholesterolemia.
Trinder Mark et al. Journal of the American College of Cardiology 2019 Jul 74(4) 512-522
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Genetic Risk Score for Coronary Disease Identifies Predispositions to Cardiovascular and Noncardiovascular Diseases.
Ntalla Ioanna, et al. Journal of the American College of Cardiology 2019 6 0. (23) 2932-2942
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Absence of FH Diagnosis Linked to Increased Risk of Premature Mortality
M O'Riordan, TCMD Heart Disease, June 5, 2019
Genetic Tools for Coronary Risk Assessment in Type 2 Diabetes: A Cohort Study From the ACCORD Clinical Trial.
Morieri Mario Luca et al. Diabetes care 2018 Nov 41(11) 2404-2413
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Vascular endothelial growth factor gene transfer therapy for coronary artery disease: A systematic review and meta-analysis.
Yuan Rong et al. Cardiovascular therapeutics 2018 Oct 36(5) e12461
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The changing status of ejection fraction as a predictor of early mortality following surgery for acquired heart disease.
Tyers G F et al. Chest 1977 Mar 71(3) 371-5
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5 reasons you could develop heart disease before 50
American Heart Association, September 14, 2018
Impact of Self-Reported Family History of Premature Cardiovascular Disease on the Outcomes of Patients Hospitalized for Acute Coronary Syndrome (from the Acute Coronary Syndrome Israel Survey [ACSIS] 2000 to 2013).
Levi Amos et al. The American journal of cardiology 2018 Jun
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Precision Medicine and Personalized Medicine in Cardiovascular Disease.
Currie Gemma et al. Advances in experimental medicine and biology 2018 1065589-605
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Familial hypercholesterolemia in very young myocardial infarction.
Li Sha et al. Scientific reports 2018 Jun 8(1) 8861
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Basic vs More Complex Definitions of Family History in the Prediction of Coronary Heart Disease: The Multi-Ethnic Study of Atherosclerosis.
Patel Jaideep et al. Mayo Clinic proceedings 2018 Mar
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ODYSSEY Outcomes Results Promising for Individuals with Familial Hypercholesterolemia
J Knowles, the FH Foundation, Mar 10, 2018
The clinical utility of gene expression testing on the diagnostic evaluation of patients presenting to the cardiologist with symptoms of suspected obstructive coronary artery disease: results from the IMPACT (Investigation of a Molecular Personalized Coronary Gene Expression Test on Cardiology Practice Pattern) trial.
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Page last reviewed:
Feb 1, 2024
Page last updated:
Apr 25, 2024
Content source:
Public Health Genomics Branch in the Division of Blood Disorders and Public Health Genomics
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National Center on Birth Defects and Developmental Disabilities
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