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Public Health Genomics and Precision Health Knowledge Base (v9.0)
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Precision Health Database|Search|Public Health Genomics and Precision Health Knowledge Base (PHGKB)
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Last data update: Apr 25, 2024
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Advancing hospital-based health technology assessment: evaluating genomic panel contracting strategies for blood tumors through a multimethodology.
Susana Afonso et al. Int J Technol Assess Health Care 2023 39(1) e76
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The Clinical Utility of FLT3 Mutation Testing in Acute Leukemia: A Canadian Consensus.
Julie Bergeron et al. Curr Oncol 2023 30(12) 10410-10436
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Management of Down Syndrome-Associated Leukemias: A Review.
Anupam Verma et al. JAMA Oncol 2023
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Molecular Heterogeneity of Pediatric AML with Atypical Promyelocytes Accumulation in Children-A Single Center Experience.
Aleksandra Borkovskaia et al. Genes 2023 14(3)
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The Clinical Spectrum, Diagnosis, and Management of GATA2 Deficiency.
Marta Santiago et al. Cancers 2023 15(5)
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A Phenogenetic Axis that Modulates Clinical Manifestation and Predicts Treatment Outcome in Primary Myeloid Neoplasms.
Qiujin Shen et al. Cancer research communications 2023 2(4) 258-276
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Comprehensive analysis of PTPN family expression and prognosis in acute myeloid leukemia.
Yong Liu et al. Frontiers in genetics 2023 131087938
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Molecular Landscape and Validation of New Genomic Classification in 2668 Adult AML Patients: Real Life Data from the PETHEMA Registry.
Sargas Claudia et al. Cancers 2023 15(2)
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Acute myeloid leukemia: challenges for diagnosis and treatment in Latin America.
Gómez-De León Andrés et al. Hematology (Amsterdam, Netherlands) 2023 28(1) 2158015
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Knowledge to date on secondary malignancy following hematopoietic cell transplantation for sickle cell disease.
Fitzhugh Courtney D et al. Hematology. American Society of Hematology. Education Program 2022 2022(1) 266-271
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Measurable residual disease by flow cytometry in acute myeloid leukemia is prognostic, independent of genomic profiling.
Ganzel Chezi et al. Leukemia research 2022 123106971
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Unified classification and risk-stratification in Acute Myeloid Leukemia.
Tazi Yanis et al. Nature communications 2022 13(1) 4622
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Screening a Targeted Panel of Genes by Next-Generation Sequencing Improves Risk Stratification in Real World Patients with Acute Myeloid Leukemia.
Matos Sónia et al. Cancers 2022 14(13)
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Pan-cancer analysis reveals distinct clinical, genomic, and immunological features of the LILRB immune checkpoint family in acute myeloid leukemia.
Xu Zi-Jun et al. Molecular therapy oncolytics 2022 2688-104
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How Genetics Can Drive Initial Therapy Choices for Older Patients with Acute Myeloid Leukemia.
Moore Jozal W et al. Current treatment options in oncology 2022
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Molecular genetic and clinical characterization of acute myeloid leukemia with trisomy 8 as the sole chromosome abnormality.
Liu Jie et al. Hematology (Amsterdam, Netherlands) 2022 27(1) 565-574
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Comprehensive mutation profile in acute myeloid leukemia patients with RUNX1-RUNX1T1 or CBFB-MYH11 fusions.
Qin Wei et al. Turkish journal of haematology : official journal of Turkish Society of Haematology 2022
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WT1 Gene Mutations, rs16754 Variant, and WT1 Overexpression as Prognostic Factors in Acute Myeloid Leukemia Patients.
Koczkodaj Dorota et al. Journal of clinical medicine 2022 11(7)
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A Predictor Combining Clinical and Genetic Factors for AML1-ETO Leukemia Patients.
Yang Min et al. Frontiers in oncology 2022 11783114
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Incorporating genetic counseling into the evaluation of pediatric bone marrow failure.
Schneider Kami Wolfe et al. Journal of genetic counseling 2021
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Adult Acute Myeloid Leukemia with the KMT2A-Mixed Lineage Leukemia T10 Fusion: An Analysis of 10 Cases Showed Common Features and Frequent Mutations in the RAS Signaling Pathway.
Cai Xiaohui et al. Acta haematologica 2021 1-7
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Prognostic impact of pre-transplant chromosomal aberrations in peripheral blood of patients undergoing unrelated donor hematopoietic cell transplant for acute myeloid leukemia.
Wang Youjin et al. Scientific reports 2021 11(1) 15004
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DNA methylation analysis improves the prognostication of acute myeloid leukemia.
Samimi Hanie et al. EJHaem 2021 2(2) 211-218
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An overview of genetic predisposition to familial hematological malignancies.
Hamadou Walid Sabri et al. Bulletin du cancer 2021
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Impact of a 40-Gene Targeted Panel Test on Physician Decision Making for Patients With Acute Myeloid Leukemia.
Barnell Erica K et al. JCO precision oncology 2021 5
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Alternative splicing redefines landscape of commonly mutated genes in acute myeloid leukemia.
Rivera Osvaldo D et al. Proceedings of the National Academy of Sciences of the United States of America 2021 118(15)
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Genome Sequencing as an Alternative to Cytogenetic Analysis in Myeloid Cancers.
Duncavage Eric J et al. The New England journal of medicine 2021 384(10) 924-935
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[Significance of Targeted Sequencing Assay for Patients with Suspected Myeloid Malignancies].
Zhang Li-Juan et al. Zhongguo shi yan xue ye xue za zhi 2020 Dec 28(6) 1985-1990
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Informed consent for genetic testing in hematology.
Marron Jonathan M et al. Hematology. American Society of Hematology. Education Program 2020 2020(1) 213-218
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Precision medicine treatment in acute myeloid leukemia using prospective genomic profiling: feasibility and preliminary efficacy of the Beat AML Master Trial
A Burd et al, Nature Medicine, October 26, 2020
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Page last reviewed:
Feb 1, 2024
Page last updated:
Apr 25, 2024
Content source:
Public Health Genomics Branch in the Division of Blood Disorders and Public Health Genomics
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National Center on Birth Defects and Developmental Disabilities
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