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Public Health Genomics and Precision Health Knowledge Base (v9.0)
PHGKB
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Precision Health Database|Search|Public Health Genomics and Precision Health Knowledge Base (PHGKB)
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Last data update: Jun 21, 2024
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MSGene: a multistate model using genetic risk and the electronic health record applied to lifetime risk of coronary artery disease.
Sarah M Urbut et al. Nat Commun 2024 15(1) 4884
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Exceptional Genetics, Generalizable Therapeutics, and Coronary Artery Disease
Influence of Polygenic Background on the Clinical Presentation of Familial Hypercholesterolemia.
Mark Trinder et al. Arterioscler Thromb Vasc Biol 2024
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Algorithm for detection and screening of familial hypercholesterolemia in Lithuanian population.
Urte Aliosaitiene et al. Lipids Health Dis 2024 23(1) 136
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Modification of coronary artery disease clinical risk factors by coronary artery disease polygenic risk score.
Buu Truong et al. Med 2024
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Enhanced identification of familial hypercholesterolemia using central laboratory algorithms.
Shirin Ibrahim et al. Atherosclerosis 2024 393117548
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Genetic testing in cardiovascular disease.
Michael P Gray et al. Med J Aust 2024
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Integration of a polygenic score into guideline-recommended prediction of cardiovascular disease.
Ling Li et al. Eur Heart J 2024
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Physical signs and atherosclerotic cardiovascular disease in familial hypercholesterolemia: the HELLAS-FH Registry.
Loukianos S Rallidis et al. J Cardiovasc Med (Hagerstown) 2024
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International Atherosclerosis Society Roadmap for Familial Hypercholesterolaemia.
Gerald F Watts et al. Glob Heart 2024 19(1) 12
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Dose-Response Associations of Lipid Traits With Coronary Artery Disease and Mortality.
Guoyi Yang et al. JAMA Netw Open 2024 7(1) e2352572
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Clinical and genetic diagnosis of familial hypercholesterolaemia in patients undergoing coronary angiography: the Ludwigshafen Risk and Cardiovascular Health Study.
Stefan Molnar et al. Eur Heart J Qual Care Clin Outcomes 2024
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Family history, socioeconomic factors, comorbidities, health behaviors, and the risk of sudden cardiac arrest.
Eujene Jung et al. Sci Rep 2023 13(1) 21341
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Dynamic Importance of Genomic and Clinical Risk for Coronary Artery Disease Over the Life Course.
Sarah M Urbut et al. medRxiv 2023
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Genetic risk, adherence to healthy lifestyle and acute cardiovascular and thromboembolic complications following SARS-COV-2 infection.
Junqing Xie et al. Nat Commun 2023 14(1) 4659
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The GenoVA study: Equitable implementation of a pragmatic randomized trial of polygenic-risk scoring in primary care.
Jason L Vassy et al. Am J Hum Genet 2023 110(11) 1841-1852
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Ancestry-specific polygenic risk scores are risk enhancers for clinical cardiovascular disease assessments.
George B Busby et al. Nat Commun 2023 14(1) 7105
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Novel Finnish-enriched variants causing severe hypercholesterolemia and their clinical impact on coronary artery disease.
Nella Junna et al. Atherosclerosis 2023 117327
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Predictive capacity of a genetic risk score for coronary artery disease in assessing recurrences and cardiovascular mortality among patients with myocardial infarction.
Luis Miguel Rincón et al. Front Cardiovasc Med 2023 101254066
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Cost-effectiveness analysis of implementing polygenic risk score in a workplace cardiovascular disease prevention program.
Deo Mujwara et al. Front Public Health 2023 111139496
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Application of genetic risk score for in-stent restenosis of second- and third-generation drug-eluting stents in geriatric patients.
Yu-Ling Hsu et al. BMC Geriatr 2023 23(1) 443
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Improving polygenic score prediction for coronary artery disease across populations of diverse ancestry
Nature Medicine, July 10, 2023
Contemporary Polygenic Scores of Low-Density Lipoprotein Cholesterol and Coronary Artery Disease Predict Coronary Atherosclerosis in Adolescents and Young Adults.
Rodrigo Guarischi-Sousa et al. Circ Genom Precis Med 2023 e004047
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A multi-ancestry polygenic risk score improves risk prediction for coronary artery disease.
Aniruddh P Patel et al. Nat Med 2023
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International Atherosclerosis Society guidance for implementing best practice in the care of familial hypercholesterolaemia.
Gerald F Watts et al. Nat Rev Cardiol 2023
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Gaps in the Care of Subjects with Familial Hypercholesterolemia: Insights from the Thai Familial Hypercholesterolemia Registry.
Poranee Ganokroj et al. J Atheroscler Thromb 2023
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[Association between clinical phenotypes of hypertrophic cardiomyopathy and Ca gene variation gene variation].
J Zhao et al. Zhonghua Xin Xue Guan Bing Za Zhi 2023 51(5) 497-503
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Genetic Testing Enables the Diagnosis of Familial Hypercholesterolemia Underdiagnosed by Clinical Criteria: Analysis of Japanese Early-Onset Coronary Artery Disease Patients.
Hiroshi Miyama et al. Cardiol Res Pract 2023 20232236422
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Reducing Premature Coronary Artery Disease in Malaysia by Early Identification of Familial Hypercholesterolaemia using FAMCAT Primary Care Screening Tool: A Mixed-Methods Evaluation Study Protocol.
Anis Safura Ramli et al. JMIR Res Protoc 2023
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Spotlight on the 2022 ESC guideline management of ventricular arrhythmias and prevention of sudden cardiac death: 10 novel key aspects.
Hilke Könemann et al. Europace 2023
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Page last reviewed:
Feb 1, 2024
Page last updated:
Jun 21, 2024
Content source:
Public Health Genomics Branch in the Division of Blood Disorders and Public Health Genomics
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National Center on Birth Defects and Developmental Disabilities
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