Published on 01/07/2016
Human Genomics across the Lifespan
Birth Defects and Child Health
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The Challenge of Analyzing the Results of Next-Generation Sequencing in Children.
Thiffault Isabelle et al. Pediatrics 2016 Jan 137 Suppl 1S3-7 -
Whole-Genome Sequencing and Disability in the NICU: Exploring Practical and Ethical Challenges.
Deem Michael J et al. Pediatrics 2016 Jan 137 Suppl 1S47-55
Cancer
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Assessment of the prognostic and predictive utility of the Breast Cancer Index (BCI): an NCIC CTG MA.14 study.
Sgroi Dennis C et al. Breast cancer research : BCR 2016 18(1) 1 -
Outcome of genetic evaluation of patients with kidney cancer referred for suspected hereditary cancer syndromes.
Stratton Kelly L et al. Urologic oncology 2015 Dec -
Exploring genomic alteration in pediatric cancer using ProteinPaint.
Zhou Xin et al. Nature genetics 2015 Dec 48(1) 4-6 -
Personalized Circulating Tumor DNA Biomarkers Dynamically Predict Treatment Response and Survival In Gynecologic Cancers.
Pereira Elena et al. PloS one 2015 10(12) e0145754 -
Initial clinical validation of Health Heritage, a patient-facing tool for personal and family history collection and cancer risk assessment.
Baumgart Leigh A et al. Familial cancer 2015 Dec -
Statewide Retrospective Review of Familial Pancreatic Cancer in Delaware, and Frequency of Genetic Mutations in Pancreatic Cancer Kindreds.
Catts Zohra Ali-Khan et al. Annals of surgical oncology 2016 Jan -
Validation of a quantitative 12-multigene expression assay (Oncotype DX(®) Colon Cancer Assay) in Korean patients with stage II colon cancer: implication of ethnic differences contributing to differences in gene expression.
Jeong Duck Hyoun et al. OncoTargets and therapy 2015 83817-25 -
Circulating tumor DNA as a non-invasive substitute to metastasis biopsy for tumor genotyping and personalized medicine in a prospective trial across all tumor types.
Lebofsky Ronald et al. Molecular oncology 2015 Apr 9(4) 783-90
Chronic Disease
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KHA-CARI Autosomal Dominant Polycystic Kidney Disease Guideline: Genetic Testing for Diagnosis.
Tchan Michel et al. Seminars in nephrology 2015 Nov 35(6) 545-549.e2 -
KHA-CARI Autosomal Dominant Polycystic Kidney Disease Guideline: Genetics and Genetic Counseling.
Patel Chirag et al. Seminars in nephrology 2015 Nov 35(6) 550-556.e1
Ethics/Policy/Law
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Changes to the Genetic Information Nondiscrimination Act Coming in 2016!
By Nicholas Beermann and Lisa McGlynn, JDSupra, December 31, 2015 -
Genomic Databases and Biobanks in Israel.
Siegal Gil et al. The Journal of law, medicine & ethics : a journal of the American Society of Law, Medicine & Ethics 2015 Dec 43(4) 766-75 -
International Guidelines for Privacy in Genomic Biobanking (or the Unexpected Virtue of Pluralism).
Thorogood Adrian et al. The Journal of law, medicine & ethics : a journal of the American Society of Law, Medicine & Ethics 2015 Dec 43(4) 690-702 -
Automatic Placement of Genomic Research Results in Medical Records: Do Researchers Have a Duty? Should Participants Have a Choice?
Prince Anya E R et al. The Journal of law, medicine & ethics : a journal of the American Society of Law, Medicine & Ethics 2015 Dec 43(4) 827-42 -
Regulation of Biobanks in France.
Rial-Sebbag Emmanuelle et al. The Journal of law, medicine & ethics : a journal of the American Society of Law, Medicine & Ethics 2015 Dec 43(4) 754-65 -
Biobanking and Privacy Laws in Australia.
Chalmers Don et al. The Journal of law, medicine & ethics : a journal of the American Society of Law, Medicine & Ethics 2015 Dec 43(4) 703-13 -
Biobanking and Privacy Law in Brazil.
Dallari Sueli Gandolfi et al. The Journal of law, medicine & ethics : a journal of the American Society of Law, Medicine & Ethics 2015 Dec 43(4) 714-25 -
Potential Psychosocial Risks of Sequencing Newborns.
Frankel Leslie Ann et al. Pediatrics 2016 Jan 137 Suppl 1S24-9 -
Genomic Databases and Biobanks in Denmark.
Hartlev Mette et al. The Journal of law, medicine & ethics : a journal of the American Society of Law, Medicine & Ethics 2015 Dec 43(4) 743-53 -
Whole-Genome Screening of Newborns? The Constitutional Boundaries of State Newborn Screening Programs.
King Jaime S et al. Pediatrics 2016 Jan 137 Suppl 1S8-S15 -
Introduction to Bioethics Special Supplement V: Ethical Issues in Genomic Testing of Children.
Lantos John D et al. Pediatrics 2016 Jan 137 Suppl 1S1-2 -
Spanish Regulation of Biobanks.
Nicolás Pilar et al. The Journal of law, medicine & ethics : a journal of the American Society of Law, Medicine & Ethics 2015 Dec 43(4) 801-15 -
Biobank/Genomic Research in Nigeria: Examining Relevant Privacy and Confidentiality Frameworks.
Nnamuchi Obiajulu et al. The Journal of law, medicine & ethics : a journal of the American Society of Law, Medicine & Ethics 2015 Dec 43(4) 776-86
Practice
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The IGNITE network: a model for genomic medicine implementation and research.
Weitzel Kristin Wiisanen et al. BMC medical genomics 2016 9(1) 1 -
Advanced nursing practice and research contributions to precision medicine.
Williams Janet K et al. Nursing outlook 2015 Nov -
Start the new year by creating a family medical history tree,
by Colleen Schrappen, St. Louis Post Dispatch, December 31, 2015 -
Computational Pathology: A Path Ahead.
Louis David N et al. Archives of pathology & laboratory medicine 2016 Jan 140(1) 41-50 -
Review and evaluation of the methodological quality of the existing guidelines and recommendations for inherited neurometabolic disorders.
Cassis Linda et al. Orphanet journal of rare diseases 2015 10(1) 164 -
Methods of genomic competency integration in practice.
Jenkins Jean et al. Journal of nursing scholarship : an official publication of Sigma Theta Tau International Honor Society of Nursing / Sigma Theta Tau 2015 May 47(3) 200-10
Heart, Lung, Blood and Sleep Diseases
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Relation Between Family History of Premature Coronary Artery Disease and the Risk of Death in Patients With Coronary Artery Disease.
Abdi-Ali Ahmed et al. The American journal of cardiology 2015 Nov
Newborn Screening
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Psychosocial Factors Influencing Parental Interest in Genomic Sequencing of Newborns.
Waisbren Susan E et al. Pediatrics 2016 Jan 137 Suppl 1S30-5 -
Parental Views on Expanded Newborn Screening Using Whole-Genome Sequencing.
Joseph Galen et al. Pediatrics 2016 Jan 137 Suppl 1S36-46 -
Supporting Parental Decisions About Genomic Sequencing for Newborn Screening: The NC NEXUS Decision Aid.
Lewis Megan A et al. Pediatrics 2016 Jan 137 Suppl 1S16-23
Pharmacogenomics
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Bringing clinical pharmacogenomics information to pharmacists: A qualitative study of information needs and resource requirements.
Romagnoli Katrina M et al. International journal of medical informatics 2016 Feb 8654-61 -
Clinical Value of CYP2C19 Genetic Testing for Guiding the Anti-platelet Therapy in a Chinese Population.
Shen De-Liang et al. Journal of cardiovascular pharmacology 2015 Nov -
Prospective DPYD genotyping to reduce the risk of fluoropyrimidine-induced severe toxicity: Ready for prime time.
Lunenburg Carin A T C et al. European journal of cancer (Oxford, England : 1990) 2015 Dec 5440-48
Reproductive Health
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Current controversies in prenatal diagnosis 3: the ethical and counseling implications of new genomic technologies: all pregnant women should be offered prenatal diagnostic genome-wide testing for prenatally identified fetal congenital anomalies.
Wilson R Douglas et al. Prenatal diagnosis 2015 Jan 35(1) 19-22 -
Expanded carrier screening: A review of early implementation and literature.
Lazarin Gabriel A et al. Seminars in perinatology 2015 Dec
News/ Reviews/Comments
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Gene Editing Tool Hailed As A Breakthrough, And It Really Is One,
NPR, December 29, 2015 -
Exercise helps fight effects of a common obesity gene,
by Samantha Craggs, CBC News, January 4, 2016 -
2015 Research Highlights — Clinical Breakthroughs,
NIH Research Matters, December 21, 2015 -
Twin Study Sheds Light on Cancer—Genetics or environment: which more closely influences cancer?
Medpage Today, January 5, 2016 -
Researchers develop powerful interactive tool to mine data from cancer genome,
Medical Xpress, December 29, 2015 -
CRISPR's Most Exciting Uses Have Nothing to Do With Gene-Editing,
by Ed Yong, the Atlantic, January 5, 2016 -
Precision Medicine, Stuck In Second Grade, Flunks Test Of Clinical Utility,
Cardio Brief, January 5, 2016 -
You have a possibly faulty gene. Should your doctor tell you?
By Patrick Skerrett, STAT, January 5, 2016 -
Twin study estimates familial risks of 23 different cancers,
Science Daily, January 5, 2016 -
Just How Much Is Cancer Due to Your Genes?
By Maggie Fox, NBC News, January 5, 2016 -
Best of 2015 on G2G: Policy & Advocacy,
Genes to Genome Blog, December 29, 2015 -
Cancer: Year in Review 2015 with Anna Barker,
by Ayanna Monteverdi, Mendelspod, December 30, 2015 -
Take It Personally - How decoding your genes might unlock the future of health care.
By Julie Dugdale, 5280 the Denver Magazine, January 2016 -
The CRISPR Patent Interference Showdown Is On: How Did We Get Here and What Comes Next?
By Jacob S. Sherkow, Law and Biosciences Blog, Stanford University, December 29, 2015 -
The Top Ten Stories in Genetics, 2015: A Bacterial Editing System Goes Viral,
by Laura Hercher, the DNA Exchange, December 30, 2015