Precision Medicine—Are We There Yet? A Narrative Review of Precision Medicine’s Applicability in Primary Care
W Evans et al, JPM, April 15, 2024 (Posted Apr 15, 2024 2PM)
Nucleic acid-based drugs for patients with solid tumours.
Sebastian G Huayamares et al. Nat Rev Clin Oncol 2024 4 (Posted Apr 10, 2024 8AM)
Dutch Pharmacogenetics Working Group (DPWG) guideline for the gene-drug interaction of CYP2C9, HLA-A and HLA-B with anti-epileptic drugs.
Lisanne E N Manson et al. Eur J Hum Genet 2024 4 (Posted Apr 04, 2024 9AM)
DNA test says it can predict opioid addiction risk. Skeptics aren’t so sure.
D Ovalle, Washington Post, March 25, 2024 (Posted Mar 25, 2024 8AM)
Cathy R Fulton et al. J Am Assoc Nurse Pract 2024
Olaparib not cost-effective as maintenance therapy for platinum-sensitive, BRCA1/2 germline-mutated metastatic pancreatic cancer.
Tarun Mehra et al. PLoS One 2024 19(4) e0301271
Patient perspectives on pharmacogenomic (PGx) testing for antidepressant prescribing in primary care: a qualitative description study.
Alexandra Cernat et al. J Community Genet 2024
The role of community engagement in promoting research participants' understanding of pharmacogenomic research results: Perspectives of stakeholders involved in HIV/AIDS research and treatment.
Sylvia Nabukenya et al. PLoS One 2024 19(4) e0299081
A New Cloud-Native Tool for Pharmacogenetic Analysis.
David Yu Yuan et al. Genes (Basel) 2024 15(3)
Implementation of CYP2C19 and CYP2D6 genotyping to guide antidepressant use in a large rural health system.
Natasha J Petry et al. Am J Health Syst Pharm 2024
Estimation of the benefit from pre-emptive genotyping based on the nationwide cohort data in South Korea.
Ki Young Huh et al. Clin Transl Sci 2024 17(3) e13772
Clinical evaluation of a low-coverage whole-genome test for detecting homologous recombination deficiency in ovarian cancer.
Romain Boidot et al. Eur J Cancer 2024 202113978
Clinical pharmacists' knowledge, attitude, perception, and beliefs about the role of pharmacogenetic testing for genes polymorphisms when prescribing mercaptopurine.
Norah O Abanmy et al. Saudi Pharm J 2024 32(4) 102022
Frequencies of CYP2C19 and CYP2D6 gene variants in a German inpatient sample with mood and anxiety disorders.
Maike Scherf-Clavel et al. World J Biol Psychiatry 2024 1-11
Real-World Data and Clinical Implications of Next-Generation Sequencing (NGS)-Based Analysis in Metastatic Breast Cancer Patients.
Fabio Canino et al. Int J Mol Sci 2024 25(5)
Empowering personalized pharmacogenomics with generative AI solutions.
Mullai Murugan et al. J Am Med Inform Assoc 2024
Exploring the impact and utility of genomic sequencing in established CKD.
Julia Jefferis et al. Clin Kidney J 2024 17(3) sfae043
The cost-effectiveness of germline BRCA testing-guided olaparib treatment in metastatic castration resistant prostate cancer.
Srinivas Teppala et al. Int J Technol Assess Health Care 2024 40(1) e14
Knowledge and attitudes on implementing cardiovascular pharmacogenomic testing.
Callan Russell et al. Clin Transl Sci 2024 17(3) e13737
A survey on awareness, knowledge and preferences toward genetic testing among the United States general public.
Shahariar Mohammed Fahim et al. Per Med 2024
Contemporary lipid-lowering management and risk of cardiovascular events in homozygous familial hypercholesterolaemia: insights from the Italian LIPIGEN Registry.
Laura D'Erasmo et al. Eur J Prev Cardiol 2024
Impact on costs and outcomes of multi-gene panel testing for advanced solid malignancies: a cost-consequence analysis using linked administrative data.
Alberto Hernando-Calvo et al. EClinicalMedicine 2024 69102443
PillHarmonics™: An Orchestrated Pharmacogenetics Medication Clinical Decision Support Service.
Robert H Dolin et al. Appl Clin Inform 2024
A Bayesian approach for investigating the pharmacogenetics of combination antiretroviral therapy in people with HIV.
Wei Jin et al. Biostatistics 2024
Opportunities for Pharmacogenetic Testing to Guide Dosing of Medications in Youths With Medicaid.
Sonya Tang Girdwood et al. JAMA Netw Open 2024 7(2) e2355707
An update review of new therapies in sickle cell disease: the prospects for drug combinations.
Sanne Lugthart et al. Expert Opin Pharmacother 2024
Genetic and non-genetic predictors of risk for opioid dependence.
Peter J Na et al. Psychol Med 2024 1-8
Using Machine Learning to Determine a Suitable Patient Population for Anakinra for the Treatment of COVID-19 Under the Emergency Use Authorization.
Liu Qi, et al. Clinical pharmacology and therapeutics 2024 0 0.
Assessing the utility of measurement methods applied in economic evaluations of pharmacogenomics applications.
Vasileios Fragoulakis et al. Pharmacogenomics 2024
Measuring Costs of Cardiovascular Disease Prevention for Patients with Familial Hypercholesterolemia in Administrative Claims Data.
Lauren E Passero et al. High Blood Press Cardiovasc Prev 2024
Modeling health outcomes associated with BRCA testing and treatment strategies for patients with metastatic pancreatic cancer.
Neeharika Agnihotri et al. Pancreatology 2024
Use of drugs with pharmacogenomics (PGx)-based dosing guidelines in a Danish cohort of persons with chronic kidney disease, both on dialysis and not on dialysis: Perspectives for prescribing optimization.
Niels Westergaard et al. Basic Clin Pharmacol Toxicol 2024
Effects of Social Determinants and Pharmacogenetic Medication Interactions on 90-Day Hospital Readmissions.
Sean David et al. Ann Fam Med 2024 21(Suppl 3)
Implementation of clopidogrel pharmacogenetic clinical decision support for a preemptive return of results program.
Christina L Aquilante et al. Am J Health Syst Pharm 2024
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About PGx PHGKB
PGx PHGKB is an online, continuously updated, searchable database of published scientific literature, CDC and NIH resources, and other materials that address the translation of genomic and other precision health discoveries into improved health care and prevention related to medications....more
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Disclaimer: Articles listed in the Public Health Knowledge Base are selected by Public Health Genomics Branch to provide current awareness of the literature and news. Inclusion in the update does not necessarily represent the views of the Centers for Disease Control and Prevention nor does it imply endorsement of the article's methods or findings. CDC and DHHS assume no responsibility for the factual accuracy of the items presented. The selection, omission, or content of items does not imply any endorsement or other position taken by CDC or DHHS. Opinion, findings and conclusions expressed by the original authors of items included in the update, or persons quoted therein, are strictly their own and are in no way meant to represent the opinion or views of CDC or DHHS. References to publications, news sources, and non-CDC Websites are provided solely for informational purposes and do not imply endorsement by CDC or DHHS.
- Page last reviewed:Feb 1, 2024
- Page last updated:Apr 25, 2024
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