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Family Health History PHGKB

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Last Posted: Nov 23, 2021
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Why Knowing Your Family’s Health Past Benefits Your Future
L Orlando, Duke University, November 2021

Knowing your family’s health history is one of the most important ways to maintain your health. It can be some of the best information doctors have to understand your risk for developing medical conditions. If you’re seeing family this holiday season, it’s a great time to talk about their past treatments and current medical needs. Asking questions about what’s impacted your loved ones will give you a more complete picture of how your own health may change in the future -- and how your doctor can help.

Stay Informed of Your Family Health History
CDC Public Health Matters Blog, November 22, 2021

Thanksgiving Day is National Family Health History Day. Family health history is a record of the diseases and health conditions in your family. Most people have family history of at least one chronic disease that makes them more likely to get that disease. Staying informed of your family’s health history can help you and your doctor prepare for and prevent diseases you are more likely to get and that can affect you later in life.

Happy Thanksgiving 2021! Family Health History in the COVID-19 Era
RF Green et al, CDC Blog Post, November 16, 2021

For a second year in a row, this Thanksgiving might not look the same as the ones before it, but some things haven’t changed. Even if you can’t see your loved ones in person, Thanksgiving is still a great time to talk to your family members about your family health history. Having one or more family members with a disease can mean that you and others in the family are more likely to get that disease. But it’s not inevitable — for many chronic diseases, knowing about your family health history can empower you to take steps that make you less likely to get diseases that run in your family.

Family Health History Social Media Campaign
NHGRI, November 2021

November is Family Health History Awareness Month! To celebrate, the National Human Genome Research Institute will host several engagement events over social media on Wednesday, November 17. We encourage you and your organizations to join in and help amplify our Institute’s mission to increase genomic literacy and family health history awareness.


news Latest News and Publications
A risk prediction tool for individuals with a family history of breast, ovarian, or pancreatic cancer: BRCAPANCPRO. External Web Site Icon
Blackford Amanda L et al. British journal of cancer 2021
Clinical Characteristics of Pancreatic and Biliary Tract Cancers Associated with Lynch Syndrome. External Web Site Icon
Takamizawa Shigemasa et al. Journal of hepato-biliary-pancreatic sciences 2021
Contribution of Family History of Head and Neck Cancer and Associated Risk Factors: Analysis of an Internet Based Risk Assessment Tool. External Web Site Icon
O'Keefe R et al. International journal of radiation oncology, biology, physics 2021 111(3S) e376
Determination of test performance of two contemporary screening tests for Lynch syndrome in endometrial cancer: A clinical trial. External Web Site Icon
Gudgeon James M et al. Gynecologic oncology 2021
Can Studying Genetically Predisposed Individuals Inform Prevention Strategies for RA? External Web Site Icon
Fowler-Woods Amanda et al. Healthcare (Basel, Switzerland) 2021 9(10)
Experience and Perceptions of a Family Health History Risk Assessment Tool among Multi-Ethnic Asian Breast Cancer Patients. External Web Site Icon
Yoon Sungwon et al. Journal of personalized medicine 2021 11(10)
Exploring the Role of Alcohol Metabolizing Genotypes in a 12-Week Clinical Trial of Naltrexone for Alcohol Use Disorder. External Web Site Icon
Castaldelli-Maia João M et al. Biomolecules 2021 11(10)
Identification of women at risk of hereditary breast-ovarian cancer among participants in a population-based breast cancer screening. External Web Site Icon
Bonelli Luigina et al. Familial cancer 2021
Pioneering BRCA1/2 Point-Of-Care Testing for Integration of Germline and Tumor Genetics in Breast Cancer Risk Management: A Vision for the Future of Translational Pharmacogenomics. External Web Site Icon
Mampunye Lwando et al. Frontiers in oncology 2021 11619817
Prospective Evaluation over 15 Years of Six Breast Cancer Risk Models. External Web Site Icon
Li Sherly X et al. Cancers 2021 13(20)
Comparing the performance of the novel FAMCAT algorithms and established case-finding criteria for familial hypercholesterolaemia in primary care. External Web Site Icon
Qureshi Nadeem et al. Open heart 2021 8(2)
Physicians' strategies for using family history data: having the data is not the same as using the data. External Web Site Icon
Taber Peter et al. JAMIA open 2021 3(3) 378-385
Clinical Impact of Pathogenic Germline Variants in Pancreatic Cancer: Results From a Multicenter, Prospective, Universal Genetic Testing Study. External Web Site Icon
Uson Pedro L S et al. Clinical and translational gastroenterology 2021 12(10) e00414
Novel Models of Genetic Education and Testing for Pancreatic Cancer Interception: Preliminary Results from the GENERATE Study. External Web Site Icon
Furniss C Sloane et al. Cancer prevention research (Philadelphia, Pa.) 2021
Family history recording in UK general practice: the lIFeLONG study. External Web Site Icon
Dineen Molly et al. Family practice 2021
Germline variant screening with targeted next generation sequencing in prostate cancer: phenotype-genotype correlation. External Web Site Icon
Çakir Ali Yavuz et al. Turkish journal of medical sciences 2021
Large-scale group genetic counseling: Evaluation of a novel service delivery model in a Canadian hereditary cancer clinic. External Web Site Icon
Lohn Zoe et al. Journal of genetic counseling 2021
Pretest Genetic Education Video Versus Genetic Counseling for Men Considering Prostate Cancer Germline Testing: A Patient-Choice Study to Address Urgent Practice Needs. External Web Site Icon
Russo Jessica et al. JCO precision oncology 2021 5
Risk-Reducing Bilateral Salpingo-Oophorectomy for Ovarian Cancer: A Review and Clinical Guide for Hereditary Predisposition Genes. External Web Site Icon
Liu Ying L et al. JCO oncology practice 2021 OP2100382
Underdiagnosis of Hereditary Colorectal Cancers Among Medicare Patients: Genetic Testing Criteria for Lynch Syndrome Miss the Mark. External Web Site Icon
Muller Charles et al. JCO precision oncology 2021 5
Uptake of genetic counseling and multi-gene panel testing among women in the Intermountain West with previous negative BRCA1 and BRCA2 results contacted for updated testing. External Web Site Icon
Mooney Ryan et al. Journal of genetic counseling 2021
Decision-making and experiences of preimplantation genetic diagnosis in inherited heart diseases: a qualitative study. External Web Site Icon
Yeates Laura et al. European journal of human genetics : EJHG 2021
Knowledge about risk factors for cancer and cancer risk behavior among patients with severe mental illness. External Web Site Icon
Grassi Luigi et al. Psycho-oncology 2021
Oncology clinic-based germline genetic testing for exocrine pancreatic cancer enables timely return of results and unveils low uptake of cascade testing. External Web Site Icon
Wang Yifan et al. Journal of medical genetics 2021
Ability of known colorectal cancer susceptibility SNPs to predict colorectal cancer risk: A cohort study within the UK Biobank. External Web Site Icon
Gafni Aviv et al. PloS one 2021 16(9) e0251469
Case-finding and genetic testing for familial hypercholesterolaemia in primary care. External Web Site Icon
Qureshi Nadeem et al. Heart (British Cardiac Society) 2021
Efficacy of a family-based cardiovascular risk reduction intervention in individuals with a family history of premature coronary heart disease in India (PROLIFIC): an open-label, single-centre, cluster randomised controlled trial. External Web Site Icon
Jeemon Panniyammakal et al. The Lancet. Global health 2021 9(10) e1442-e1450
Evaluating Primary Care Providers' Readiness for Delivering Genetic and Genomic Services to Underserved Populations. External Web Site Icon
Sharma Yashoda et al. Public health genomics 2021 1-10
Familial Hypercholesterolemia in Patients with Acute Coronary Syndrome: Genetic Insights from EXPLORE-J. External Web Site Icon
Harada-Shiba Mariko et al. Journal of atherosclerosis and thrombosis 2021
Importance of Family History of Colorectal Cancer In Situ Versus Invasive Colorectal Cancer: A Nationwide Cohort Study. External Web Site Icon
Tian Yu et al. Journal of the National Comprehensive Cancer Network : JNCCN 2021 1-6

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Disclaimer: Articles listed in the Public Health Knowledge Base are selected by the CDC Office of Public Health Genomics to provide current awareness of the literature and news. Inclusion in the update does not necessarily represent the views of the Centers for Disease Control and Prevention nor does it imply endorsement of the article's methods or findings. CDC and DHHS assume no responsibility for the factual accuracy of the items presented. The selection, omission, or content of items does not imply any endorsement or other position taken by CDC or DHHS. Opinion, findings and conclusions expressed by the original authors of items included in the update, or persons quoted therein, are strictly their own and are in no way meant to represent the opinion or views of CDC or DHHS. References to publications, news sources, and non-CDC Websites are provided solely for informational purposes and do not imply endorsement by CDC or DHHS.

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