Last Posted: May 21, 2024
Spotlight
Latest News and Publications
A murine model of post-acute neurological sequelae following SARS-CoV-2 variant infection.
Singh Ankita, et al. Frontiers in immunology 2024 0 0. 1384516
A scoping review of global SARS-CoV-2 wastewater-based epidemiology in light of COVID-19 pandemic.
Rashid Siti Aishah, et al. Heliyon 2024 0 0. (9) e30600
Associations between genetic mutations in different SARS-CoV-2 strains and negative conversion time of viral RNA among imported cases in Hangzhou: a cross-sectional study.
Wang Yi, et al. Virus research 2024 0 0. 199400
Elevated pretreatment serum apolipoprotein E level associated with poor prognosis of patients with COVID-19 during the omicron BA.5 and BF.7 wave.
Gong Shengping, et al. Journal of medical virology 2024 0 0. (5) e29673
From wild-type to Omicron: changes in SARS-CoV-2 hospital cluster dynamics. Observations from a German tertiary care hospital.
Kohlmorgen Britta, et al. GMS hygiene and infection control 2024 0 0. Doc19
Immune evasiveness of SARS-CoV-2 variants and vaccine selection.
Inghammar Malin, et al. The Lancet. Infectious diseases 2024 0 0.
Interchangeability of different COVID-19 vaccine platforms as booster doses: A phase 3 study mimicking real-world practice.
Ann Costa Clemens Sue, et al. Vaccine 2024 0 0.
Original COVID-19 priming regimen impacts the immunogenicity of bivalent BA.1 and BA.5 boosters.
Zaeck Luca M, et al. Nature communications 2024 0 0. (1) 4224
Relative vaccine protection, disease severity, and symptoms associated with the SARS-CoV-2 omicron subvariant BA.2.86 and descendant JN.1 in Denmark: a nationwide observational study.
Moustsen-Helms Ida Rask, et al. The Lancet. Infectious diseases 2024 0 0.
The Canadian VirusSeq Data Portal & Duotang: open resources for SARS-CoV-2 viral sequences and genomic epidemiology.
Erin E Gill et al. ArXiv 2024 5
A reduced proteomic signature in critically ill Covid-19 patients determined with plasma antibody micro-array and machine learning.
Patel Maitray A, et al. Clinical proteomics 2024 0 0. (1) 33
Real-time forecasting of COVID-19-related hospital strain in France using a non-Markovian mechanistic model.
Massey Alexander, et al. PLoS computational biology 2024 0 0. (5) e1012124
TYK2, IFITM3, IFNAR2 and OAS3 single-nucleotide polymorphisms among severe COVID-19 ICU patients in Morocco.
Benmansour R, et al. International journal of immunopathology and pharmacology 2024 0 0. 3946320241257241
Post-market surveillance of six COVID-19 point-of-care tests using pre-Omicron and Omicron SARS-CoV-2 variants.
Exner Hannah M, et al. Microbiology spectrum 2024 0 0. e0016324
Environmental Surveillance of Flood Control Infrastructure Impacted by Unsheltered Individuals Leads to the Detection of SARS-CoV-2 and Novel Mutations in the Spike Gene.
Anthony Harrington et al. Environ Sci Technol Lett 2024 5 (5) 410-417
Genomic surveillance and serological profile of SARS-CoV-2 variants circulating in Macaé and nearby cities, southeastern Brazil.
da Silva Amanda Cristina Veiga Fernandes, et al. Frontiers in microbiology 2024 0 0. 1386271
Pediatric hereditary angioedema attack triggered by COVID-19: A case report.
Ishikawa Jintaro, et al. Pediatrics international : official journal of the Japan Pediatric Society 2024 0 0. (1) e15752
Presence of SARS-CoV-2 RNA in COVID-19 survivors with post-COVID symptoms 2 years after hospitalization: The VIPER study.
Fernández-de-Las-Peñas César, et al. Journal of medical virology 2024 0 0. (5) e29676
PRIEST: predicting viral mutations with immune escape capability of SARS-CoV-2 using temporal evolutionary information.
Saha Gourab, et al. Briefings in bioinformatics 2024 0 0. (3)
Radiological Features of Herpetic Encephalitis in Children.
Pham Thai Son, et al. Pediatric neurology 2024 0 0. 99-105
Spotlight
High-resolution African HLA resource uncovers HLA-DRB1 expression effects underlying vaccine response
(Posted May 14, 2024 3PM)
From the abstract: " How human genetic variation contributes to vaccine effectiveness in infants is unclear, and data are limited on these relationships in populations with African ancestries. We undertook genetic analyses of vaccine antibody responses in infants from Uganda (n=1391), Burkina Faso (n=353) and South Africa (n=755), identifying associations between human leukocyte antigen (HLA) and antibody response for five of eight tested antigens spanning pertussis, diphtheria and hepatitis B vaccines. In addition, through HLA typing 1,702 individuals from 11 populations of African ancestry derived predominantly from the 1000 Genomes Project, we constructed an imputation resource, fine-mapping class II HLA-DR and DQ associations explaining up to 10% of antibody response variance in our infant cohorts. "
Vaccine effectiveness against emerging COVID-19 variants using digital health data
(Posted May 09, 2024 6PM)
From the abstract: " Here, we develop a methodology for identifying changes in vaccine effectiveness and COVID-19 symptomatology using the University of Maryland COVID Trends and Impact Survey data from three middle-income countries (Guatemala, Mexico, and South Africa). We implement conditional logistic regression to develop estimates of vaccine effectiveness conditioned on the prevalence of various definitions of self-reported COVID-like illness in lieu of confirmed diagnostic test results. Results: We highlight a reduction in vaccine effectiveness during Omicron-dominated waves of infections when compared to periods dominated by the Delta variant."
Rapid pathogen surveillance: field-ready sequencing solutions
(Posted May 03, 2024 5PM)
From the article: "Genetic sequencing of pathogens has revolutionized the surveillance of infectious diseases, empowering scientists and health officials to anticipate and respond effectively to outbreaks. Despite their transformative potential, next-generation sequencing technologies have traditionally been inaccessible to many in the global scientific community, particularly in the Global South. This is primarily due to the prohibitively high capital costs and a widespread deficiency in laboratory infrastructure and genomics expertise. Ironically, it is in these regions where genomic surveillance could yield the most crucial insights, underscoring the urgent need for equitable access to such transformative technologies. "
Bird flu virus has been spreading in US cows for months, RNA reveals Genomic analysis suggests that the outbreak probably began in December or January, but a shortage of data is hampering efforts to pin down the source.
(Posted Apr 29, 2024 11AM)
From the article: "A strain of highly pathogenic avian influenza has been silently spreading in US cattle for months, according to preliminary analysis of genomic data. The outbreak is likely to have begun when the virus jumped from an infected bird into a cow, probably around late December or early January. This implies a protracted, undetected spread of the virus — suggesting that more cattle across the United States, and even in neighbouring regions, could have been infected with avian influenza than currently reported. These conclusions are based on swift and summary analyses by researchers, following a dump of genomic data by the US Department of Agriculture (USDA) into a public repository earlier this week. "
Latest News and Publications
Singh Ankita, et al. Frontiers in immunology 2024 0 0. 1384516
A scoping review of global SARS-CoV-2 wastewater-based epidemiology in light of COVID-19 pandemic.
Rashid Siti Aishah, et al. Heliyon 2024 0 0. (9) e30600
Associations between genetic mutations in different SARS-CoV-2 strains and negative conversion time of viral RNA among imported cases in Hangzhou: a cross-sectional study.
Wang Yi, et al. Virus research 2024 0 0. 199400
Elevated pretreatment serum apolipoprotein E level associated with poor prognosis of patients with COVID-19 during the omicron BA.5 and BF.7 wave.
Gong Shengping, et al. Journal of medical virology 2024 0 0. (5) e29673
From wild-type to Omicron: changes in SARS-CoV-2 hospital cluster dynamics. Observations from a German tertiary care hospital.
Kohlmorgen Britta, et al. GMS hygiene and infection control 2024 0 0. Doc19
Immune evasiveness of SARS-CoV-2 variants and vaccine selection.
Inghammar Malin, et al. The Lancet. Infectious diseases 2024 0 0.
Interchangeability of different COVID-19 vaccine platforms as booster doses: A phase 3 study mimicking real-world practice.
Ann Costa Clemens Sue, et al. Vaccine 2024 0 0.
Original COVID-19 priming regimen impacts the immunogenicity of bivalent BA.1 and BA.5 boosters.
Zaeck Luca M, et al. Nature communications 2024 0 0. (1) 4224
Relative vaccine protection, disease severity, and symptoms associated with the SARS-CoV-2 omicron subvariant BA.2.86 and descendant JN.1 in Denmark: a nationwide observational study.
Moustsen-Helms Ida Rask, et al. The Lancet. Infectious diseases 2024 0 0.
The Canadian VirusSeq Data Portal & Duotang: open resources for SARS-CoV-2 viral sequences and genomic epidemiology.
Erin E Gill et al. ArXiv 2024 5
A reduced proteomic signature in critically ill Covid-19 patients determined with plasma antibody micro-array and machine learning.
Patel Maitray A, et al. Clinical proteomics 2024 0 0. (1) 33
Real-time forecasting of COVID-19-related hospital strain in France using a non-Markovian mechanistic model.
Massey Alexander, et al. PLoS computational biology 2024 0 0. (5) e1012124
TYK2, IFITM3, IFNAR2 and OAS3 single-nucleotide polymorphisms among severe COVID-19 ICU patients in Morocco.
Benmansour R, et al. International journal of immunopathology and pharmacology 2024 0 0. 3946320241257241
Post-market surveillance of six COVID-19 point-of-care tests using pre-Omicron and Omicron SARS-CoV-2 variants.
Exner Hannah M, et al. Microbiology spectrum 2024 0 0. e0016324
Environmental Surveillance of Flood Control Infrastructure Impacted by Unsheltered Individuals Leads to the Detection of SARS-CoV-2 and Novel Mutations in the Spike Gene.
Anthony Harrington et al. Environ Sci Technol Lett 2024 5 (5) 410-417
Genomic surveillance and serological profile of SARS-CoV-2 variants circulating in Macaé and nearby cities, southeastern Brazil.
da Silva Amanda Cristina Veiga Fernandes, et al. Frontiers in microbiology 2024 0 0. 1386271
Pediatric hereditary angioedema attack triggered by COVID-19: A case report.
Ishikawa Jintaro, et al. Pediatrics international : official journal of the Japan Pediatric Society 2024 0 0. (1) e15752
Presence of SARS-CoV-2 RNA in COVID-19 survivors with post-COVID symptoms 2 years after hospitalization: The VIPER study.
Fernández-de-Las-Peñas César, et al. Journal of medical virology 2024 0 0. (5) e29676
PRIEST: predicting viral mutations with immune escape capability of SARS-CoV-2 using temporal evolutionary information.
Saha Gourab, et al. Briefings in bioinformatics 2024 0 0. (3)
Radiological Features of Herpetic Encephalitis in Children.
Pham Thai Son, et al. Pediatric neurology 2024 0 0. 99-105
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Disclaimer: Articles listed in the Public Health Knowledge Base are selected by Public Health Genomics Branch to provide current awareness of the literature and news. Inclusion in the update does not necessarily represent the views of the Centers for Disease Control and Prevention nor does it imply endorsement of the article's methods or findings. CDC and DHHS assume no responsibility for the factual accuracy of the items presented. The selection, omission, or content of items does not imply any endorsement or other position taken by CDC or DHHS. Opinion, findings and conclusions expressed by the original authors of items included in the update, or persons quoted therein, are strictly their own and are in no way meant to represent the opinion or views of CDC or DHHS. References to publications, news sources, and non-CDC Websites are provided solely for informational purposes and do not imply endorsement by CDC or DHHS.