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Genome-Wide Association Study of VKORC1 and CYP2C9 on acenocoumarol dose, stroke recurrence and intracranial haemorrhage in Spain. Scientific reports 2020 Feb 10 (1): 2806. Cullell Natalia, Carrera Caty, Muiño Elena, Torres-Aguila Nuria-Paz, Cárcel-Márquez Jara, González-Sánchez Jonathan, Gallego-Fabrega Cristina, Molina Jessica, Besora Sarah, Sotoca Javier, Buongiorno Maria-Teresa, Jiménez-Conde Jordi, Giralt-Steinhauer Eva, de Torres-Chacón Reyes, Montaner Joan, Mancha Fernando, Cabezas Juan A, Martí-Fàbregas Joan, Prats-Sánchez Luis, Camps-Renom Pol, Purroy Francisco, Cambray Serafi, Freijo María Del Mar, Vives-Bauzá Cristòfol, Tur Silvia, Font Maria-Àngels, López-Cancio Elena, Hernandez-Perez Maria, Obach Victor, Calleja Ana, Arenillas Juan, Rodríguez-Yáñez Manuel, Castillo José, Sobrino Tomas, Fernández-Cádenas Israel, Krupinski Jer |
Effect of gene-gene and gene-environment interaction on the risk of first-ever stroke and poststroke death. Molecular genetics & genomic medicine 2019 Jul e846. Feng Congrui, Yang Yunyun, Yang Shujun, Tu Xin, Wang Yibo, Song Yiqing, Hui Rutai, Zhang Wei |
Genetic polymorphisms associated with the prevalence of retinal vein occlusion in a Greek population. International ophthalmology 2019 May . Christodoulou Aikaterini, Bagli Eleni, Gazouli Maria, Moschos Marilita M, Kitsos Georgi |
Warfarin loading dose guided by pharmacogenetics is effective and safe in cardioembolic stroke patients - a randomized, prospective study. The pharmacogenomics journal 2019 Jan . Ruzickova Tereza, Sramek Martin, Kaplan Vojtech, Kumstyrova Simona, Lacinova Zuzana, Jansky Petr, Magerova Hana, Sarbochova Ivana, Schwabova Jaroslava Paulasova, Matoska Vaclav, Tomek Al |
The Influence of CYP2C9 and VKORC1 Gene Polymorphisms on the Response to Warfarin in Egyptians. Indian journal of hematology & blood transfusion : an official journal of Indian Society of Hematology and Blood Transfusion 2018 Apr 34 (2): 328-336. Bedewy Ahmed M L, Showeta Salah, Mostafa Mostafa Hasan, Kandil Lamia Sae |
The rs2108622 polymorphism is related to the early risk of ischemic stroke in non-valvular atrial fibrillation subjects under oral anticoagulation. The pharmacogenomics journal 2017 Dec . Colàs-Campàs L, Royo J L, Montserrat M V, Marzo C, Molina-Seguín J, Benabdelhak I, Cambray S, Purroy |
Genetic and Non-Genetic Factors Affecting the Quality of Anticoagulation Control and Vascular Events in Atrial Fibrillation. Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association 2017 Apr . Park Yun Kyung, Lee Mi Ji, Kim Jae Ha, Lee Jin Soo, Park Rae Woong, Kim Gyeong-Moon, Chung Chin-Sang, Lee Kwang Ho, Kim June Soo, Lee Soo-Youn, Bang Oh You |
Factors influencing quality of anticoagulation control and warfarin dosage in patients after aortic valve replacement within the 3 months of follow up. Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 2016 Jun 67 (3): 385-93. Wypasek E, Mazur P, Bochenek M, Awsiuk M, Grudzien G, Plincer D, Undas |
Comparison of Aspirin and Naoxintong Capsule () with Adjusted-Dose Warfarin in Elderly Patients with High-Risk of Non-Valvular Atrial Fibrillation and Genetic Variants of Vitamin K Epoxide Reductase. Chinese journal of integrative medicine 2016 Feb . Wang Huan, Zhou Xiao-Kai, Zheng Li-Fan, Wu Xiao-Ying, Chen H |
G-1639A but Not C1173T VKORC1 Gene Polymorphism Is Related to Ischemic Stroke and Its Various Risk Factors in Ukrainian Population. BioMed research international 2016 2016 1298198. Dubovyk Yevhen I, Harbuzova Viktoriia Yu, Ataman Alexander |
[Association of allelic polymorphisms of genes matrix Gla-protein system with ischemic atherothrombotic stroke]. Fiziolohichny? zhurnal (Kiev, Ukraine : 1994) 2015 61 (1): 19-27. Garbuzova V Yu, Stroy D A, Dosenko V E, Dubovyk Ye I, Borodenko A O, Shimko K A, Obukhova O A, Ataman O |
Prevalence of genetic polymorphisms of CYP2C9 and VKORC1 - implications for warfarin management and outcome in Croatian patients with acute stroke. Journal of the neurological sciences 2014 Aug 343 (1-2): 30-5. Supe Svjetlana, Božina Nada, Matijevi? Vesna, Bazina Antonela, Mišmaš Antonija, Ljevak Josip, Alvir Domagoj, Habek Mario, Poljakovi? Zdrav |
VKORC1 and CYP2C9 genotypes in Egyptian patients with warfarin resistance. Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis 2014 Jun . Azzam Hanan, Elwakeel Hossam, Awad Ibrahim, El-Farahaty Reham, El-Gilany Abdel-Hady, El-Sharawy Sola |
VKORC1 and CYP2C9 Genotype Variations in Relation to Warfarin Dosing in Korean Stroke Patients. Journal of stroke 2013 May 15 (2): 115-21. Park Sea Mi, Lee Jong-Keuk, Chun Sa Il, Lee Hae In, Kwon Sun U, Kang Dong-Wha, Kim Jong |
Association of functional VKORC1 promoter polymorphism with occurrence and clinical aspects of ischemic stroke in a Greek population. Disease markers 2013 35 (6): 641-6. Ragia Georgia, Marousi Stella, Ellul John, Manolopoulos Vangelis G, Tavridou An |
Dabigatran versus warfarin under standard or pharmacogenetic-guided management for the prevention of stroke and systemic thromboembolism in patients with atrial fibrillation: a cost/utility analysis using an analytic decision model. Thrombosis journal 2013 11 (1): 14. Nshimyumukiza Léon, Duplantie Julie, Gagnon Mathieu, Douville Xavier, Fournier Diane, Lindsay Carmen, Parent Marc, Milot Alain, Giguère Yves, Gagné Christian, Rousseau François, Reinharz Dani |
Frequency of VKORC1 (C1173T) and CYP2C9 genetic polymorphisms in Egyptians and their influence on warfarin maintenance dose: proposal for a new dosing regimen. International journal of laboratory hematology 2012 Oct 34 (5): 517-24. El Din M S, Amin D G, Ragab S B, Ashour E E, Mohamed M H, Mohamed A |
Genotype polymorphisms of GGCX, NQO1, and VKORC1 genes associated with risk susceptibility in patients with large-artery atherosclerotic stroke. Clinica chimica acta; international journal of clinical chemistry 2010 Jun 411 (11-12): 840-5. Shyu Hann-Yeh, Fong Chin-Shih, Fu Yi-Ping, Shieh Jia-Ching, Yin Jiu-Haw, Chang Ching-Yi, Wang Hsiao-Wei, Cheng Chun-W |
Vitamin K epoxide reductase complex subunit 1 gene polymorphism is associated with atherothrombotic complication after drug-eluting stent implantation: 2-Center prospective cohort study. American heart journal 2009 May 157 (5): 908-12. Suh Jung-Won, Baek Sang-Hong, Park Jin-Shik, Kang Hyun-Jae, Chae In-Ho, Choi Dong-Ju, Park Hun-Jun, Kim Pum-Joon, Seung Ki-Bae, Kim Hyo-S |
A genome-wide association study confirms VKORC1, CYP2C9, and CYP4F2 as principal genetic determinants of warfarin dose.
![]() PLoS genetics 2009 Mar 5 (3): e1000433. Takeuchi Fumihiko, McGinnis Ralph, Bourgeois Stephane, Barnes Chris, Eriksson Niclas, Soranzo Nicole, Whittaker Pamela, Ranganath Venkatesh, Kumanduri Vasudev, McLaren William, Holm Lennart, Lindh Jonatan, Rane Anders, Wadelius Mia, Deloukas Pan |
A vitamin K epoxide reductase-oxidase complex gene polymorphism (-1639G>A) and interindividual variability in the dose-effect of vitamin K antagonists. Journal of applied genetics 2009 50 (4): 399-403. Stepien E, Branicka A, Ciesla-Dul M, Undas |
Pharmacogenetic testing for guiding de novo phenprocoumon therapy in stroke patients. Cerebrovascular diseases (Basel, Switzerland) 2009 28 (5): 468-71. Arnold Marie-Luise, Grond-Ginsbach Caspar, Kloss Manja, Di Mascio Maria-Teresa, Veltkamp Roland, Ringleb Peter, Lichy Christo |
Prevalence of combinatorial CYP2C9 and VKORC1 genotypes in Puerto Ricans: implications for warfarin management in Hispanics. Ethnicity & disease 2009 19 (4): 390-5. Duconge Jorge, Cadilla Carmen L, Windemuth Andreas, Kocherla Mohan, Gorowski Krystyna, Seip Richard L, Bogaard Kali, Renta Jessica Y, Piovanetti Paola, D'Agostino Darrin, Santiago-Borrero Pedro J, Ruaño Gualber |
Single nucleotide polymorphisms in the VKORC1 gene and the risk of stroke in the Southern German population. Thrombosis and haemostasis 2008 Oct 100 (4): 614-7. Arnold Marie-Luise, Lichy Christoph, Werner Inge, Radbruch Alexander, Wagner Simone, Grond-Ginsbach Casp |
Functional promoter polymorphism in the VKORC1 gene is no major genetic determinant for coronary heart disease in Northern Germans. Thrombosis and haemostasis 2007 Jun 97 (6): 998-1002. Watzka Matthias, Nebel Almut, El Mokhtari Nour Eddine, Ivandic Boris, Müller Jens, Schreiber Stefan, Oldenburg Johann |
Genotypes of vitamin K epoxide reductase, gamma-glutamyl carboxylase, and cytochrome P450 2C9 as determinants of daily warfarin dose in Japanese patients. Thrombosis research 2007 120 (2): 181-6. Kimura Rina, Miyashita Kotaro, Kokubo Yoshihiro, Akaiwa Yasuhisa, Otsubo Ryoichi, Nagatsuka Kazuyuki, Otsuki Toshiho, Okayama Akira, Minematsu Kazuo, Naritomi Hiroaki, Honda Shigenori, Tomoike Hitonobu, Miyata Toshiyu |
VKORC1 haplotypes are associated with arterial vascular diseases (stroke, coronary heart disease, and aortic dissection). Circulation 2006 Mar 113 (12): 1615-21. Wang Yibo, Zhang Weili, Zhang Yuhui, Yang Yuejin, Sun Lizhong, Hu Shengshou, Chen Jilin, Zhang Channa, Zheng Yi, Zhen Yisong, Sun Kai, Fu Chunyan, Yang Tao, Wang Jianwei, Sun Jing, Wu Haiying, Glasgow Wayne C, Hui Rut |
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- Page last updated:May 20, 2022
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